| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.447203 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.261672 |
| MT2A | metallothionein 2A | 0.176841 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0978572 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0825043 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0811979 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0805611 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0796214 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0790611 |
| FKBP5 | FK506 binding protein 5 | 0.0723582 |
| LOX | lysyl oxidase | 0.0643075 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0620305 |
| TMSB10 | thymosin beta 10 | 0.0601235 |
| LDHA | lactate dehydrogenase A | 0.0600428 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0529558 |
| PCBP3 | poly(rC) binding protein 3 | 0.052643 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0514486 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0502607 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0491663 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0438334 |
| MYOF | myoferlin | 0.0430335 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0430233 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0421598 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0421204 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0418709 |
| ENO1 | enolase 1, (alpha) | 0.0415992 |
| CENPF | centromere protein F, 350/400kDa | 0.0404228 |
| IRS2 | insulin receptor substrate 2 | 0.0382418 |
| ANGPTL4 | angiopoietin-like 4 | 0.0379882 |
| PCNX1 | pecanex 1 | 0.037163 |
| HMGB2 | high mobility group box 2 | 0.0352654 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0343687 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0324716 |
| AHNAK | AHNAK nucleoprotein | 0.031045 |
| MT1E | metallothionein 1E | 0.0310315 |
| TXNIP | thioredoxin interacting protein | 0.0302145 |
| TNS3 | tensin 3 | 0.0293176 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0291368 |
| DNER | delta/notch-like EGF repeat containing | 0.0287687 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0284988 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0282279 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0277994 |
| RTN4 | reticulon 4 | 0.0268877 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0268663 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0266459 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0266206 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0266132 |
| MT1X | metallothionein 1X | 0.0264937 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0255939 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0246574 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244146 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0241847 |
| BCL2L1 | BCL2-like 1 | 0.024132 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0238834 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.023708 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0236826 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0233953 |
| DST | dystonin | 0.0232892 |
| MED13L | mediator complex subunit 13-like | 0.0229939 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0228628 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0228078 |
| TGFB2 | transforming growth factor, beta 2 | 0.022314 |
| THBS1 | thrombospondin 1 | 0.0222481 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0218846 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0217609 |
| RNF220 | ring finger protein 220 | 0.0216372 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0212988 |
| FAM13A | family with sequence similarity 13, member A | 0.0212691 |
| CD109 | CD109 molecule | 0.0212296 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0207904 |
| LAMB1 | laminin, beta 1 | 0.0205214 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0200771 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0200641 |
| TPM3 | tropomyosin 3 | 0.0197888 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0195725 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0194429 |
| SET | SET nuclear proto-oncogene | 0.0193135 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0191428 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0191017 |
| TPR | translocated promoter region, nuclear basket protein | 0.0190264 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0189242 |
| CUL4B | cullin 4B | 0.0188961 |
| RPL3 | ribosomal protein L3 | 0.0180069 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0179567 |
| TPX2 | TPX2, microtubule-associated | 0.0176611 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0176447 |
| MSN | moesin | 0.0175427 |
| KIF5B | kinesin family member 5B | 0.0175417 |
| PKM | pyruvate kinase, muscle | 0.0171249 |
| KLF9 | Kruppel-like factor 9 | 0.0171176 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0169425 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0167849 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0167659 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0165064 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0164835 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0163959 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0162656 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0161928 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0161165 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0160669 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.297247 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.173814 |
| VIM | vimentin | -0.148546 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.127508 |
| EXT1 | exostosin glycosyltransferase 1 | -0.123991 |
| CDH13 | cadherin 13 | -0.116824 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.111174 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.105947 |
| NDRG1 | N-myc downstream regulated 1 | -0.09218 |
| DTNA | dystrobrevin, alpha | -0.0643627 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0623127 |
| COL5A1 | collagen, type V, alpha 1 | -0.0620007 |
| PDE10A | phosphodiesterase 10A | -0.0599557 |
| NAV1 | neuron navigator 1 | -0.0593477 |
| CD44 | CD44 molecule (Indian blood group) | -0.0571812 |
| STC1 | stanniocalcin 1 | -0.0553388 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0549495 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0525266 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0517346 |
| HMGA2 | high mobility group AT-hook 2 | -0.0494937 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0483255 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0460783 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.041062 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0400199 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0384795 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0384681 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0374111 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0373772 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0372125 |
| IER3 | immediate early response 3 | -0.035995 |
| MYO10 | myosin X | -0.0356988 |
| GRB10 | growth factor receptor-bound protein 10 | -0.03566 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0345977 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0343146 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0337697 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0334979 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0315768 |
| ATXN1 | ataxin 1 | -0.0312113 |
| INHBA | inhibin, beta A | -0.0310798 |
| IL11 | interleukin 11 | -0.0301656 |
| INTS6 | integrator complex subunit 6 | -0.0297032 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0296008 |
| EGR1 | early growth response 1 | -0.0295209 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0288615 |
| CDCP1 | CUB domain containing protein 1 | -0.0280976 |
| NGLY1 | N-glycanase 1 | -0.0275404 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0275336 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0274147 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0265524 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264989 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0264732 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0258509 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0256513 |
| ASPH | aspartate beta-hydroxylase | -0.0256432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0253098 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.025075 |
| IL1B | interleukin 1, beta | -0.0250461 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0248299 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0244892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0243602 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0243214 |
| ADM | adrenomedullin | -0.0241448 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0240809 |
| RAI14 | retinoic acid induced 14 | -0.023988 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0239198 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0235986 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0235442 |
| CFAP20DC | CFAP20 domain containing | -0.0233414 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0232153 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0231264 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0231059 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0230322 |
| CCND1 | cyclin D1 | -0.0229731 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.022914 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0220444 |
| RPL12 | ribosomal protein L12 | -0.021879 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0214313 |
| LAMB3 | laminin, beta 3 | -0.0213939 |
| SEPTIN9 | septin 9 | -0.0213659 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0213451 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0212099 |
| CADM1 | cell adhesion molecule 1 | -0.0211183 |
| MAP1B | microtubule-associated protein 1B | -0.0210173 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0209146 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0208972 |
| NUMB | numb homolog (Drosophila) | -0.0208553 |
| SQSTM1 | sequestosome 1 | -0.0205484 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0203266 |
| RASA3 | RAS p21 protein activator 3 | -0.0201058 |
| CANX | calnexin | -0.0200753 |
| RCOR1 | REST corepressor 1 | -0.020043 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0200029 |
| NABP1 | nucleic acid binding protein 1 | -0.0199506 |
| FBXO11 | F-box protein 11 | -0.0198216 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0195999 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0195382 |
| FRMD4A | FERM domain containing 4A | -0.0194294 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0192937 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.019049 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0187911 |
