| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.41905 |
| COL6A3 | collagen, type VI, alpha 3 | 0.321142 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.121632 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.10485 |
| LOX | lysyl oxidase | 0.0999105 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0930785 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0892219 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.085098 |
| LDHA | lactate dehydrogenase A | 0.0845113 |
| VEGFA | vascular endothelial growth factor A | 0.0663922 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0593241 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0588839 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0587113 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.055398 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0545778 |
| HMGA2 | high mobility group AT-hook 2 | 0.0526187 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0508739 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0505021 |
| MT2A | metallothionein 2A | 0.0472287 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.045402 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0453551 |
| COL5A1 | collagen, type V, alpha 1 | 0.0453365 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0437819 |
| PRELID2 | PRELI domain containing 2 | 0.0428833 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0418227 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0389185 |
| NRP1 | neuropilin 1 | 0.0388513 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0386032 |
| MYO1B | myosin IB | 0.0384939 |
| JAK2 | Janus kinase 2 | 0.0373138 |
| ANGPTL4 | angiopoietin-like 4 | 0.0359995 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0359838 |
| CCN4 | cellular communication network factor 4 | 0.0345846 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0342107 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0340863 |
| PTEN | phosphatase and tensin homolog | 0.0339858 |
| CD109 | CD109 molecule | 0.0337931 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0328239 |
| MT1X | metallothionein 1X | 0.0327882 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0315996 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0311347 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.031116 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0307599 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0296264 |
| MED13L | mediator complex subunit 13-like | 0.0293072 |
| DNER | delta/notch-like EGF repeat containing | 0.0288982 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0285141 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0282127 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0281623 |
| ZFHX3 | zinc finger homeobox 3 | 0.0273245 |
| IL1R1 | interleukin 1 receptor, type I | 0.0264339 |
| IL6ST | interleukin 6 signal transducer | 0.0257464 |
| TOP1 | topoisomerase (DNA) I | 0.025616 |
| MGP | matrix Gla protein | 0.0248588 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.024668 |
| ANKRD28 | ankyrin repeat domain 28 | 0.024426 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0232012 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0227334 |
| UTRN | utrophin | 0.0221106 |
| FOXO3 | forkhead box O3 | 0.0220214 |
| TNS1 | tensin 1 | 0.0206801 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0206333 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0203818 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0202897 |
| HIP1 | huntingtin interacting protein 1 | 0.0199034 |
| NAV1 | neuron navigator 1 | 0.019845 |
| GLIS3 | GLIS family zinc finger 3 | 0.0197654 |
| FKBP5 | FK506 binding protein 5 | 0.0197187 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0196517 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0188464 |
| FAM13A | family with sequence similarity 13, member A | 0.0186253 |
| POTEF | POTE ankyrin domain family, member F | 0.0185091 |
| NAV2 | neuron navigator 2 | 0.0181114 |
| DCN | decorin | 0.0177885 |
| COL5A2 | collagen, type V, alpha 2 | 0.0177198 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.017707 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0176911 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0175507 |
| RPL3 | ribosomal protein L3 | 0.0175229 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0174949 |
| EFNA5 | ephrin-A5 | 0.0174578 |
| ZNF395 | zinc finger protein 395 | 0.0174048 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0173374 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0173181 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0171825 |
| TRAM2 | translocation associated membrane protein 2 | 0.0171468 |
| JAK1 | Janus kinase 1 | 0.0170625 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.016637 |
| MSN | moesin | 0.0165768 |
| PLEC | plectin | 0.016575 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0163817 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0163246 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0161748 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0160655 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0159893 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.01587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0158697 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0156702 |
| DCLK1 | doublecortin-like kinase 1 | 0.015639 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0156311 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.264195 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.210496 |
| VIM | vimentin | -0.124373 |
| CD44 | CD44 molecule (Indian blood group) | -0.101086 |
| IER3 | immediate early response 3 | -0.101075 |
| COL1A1 | collagen, type I, alpha 1 | -0.0930495 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0903767 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.081306 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0806885 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0701516 |
| CADM1 | cell adhesion molecule 1 | -0.0630573 |
| PTMA | prothymosin, alpha | -0.0628638 |
| NDRG1 | N-myc downstream regulated 1 | -0.0628138 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0562356 |
| TMSB10 | thymosin beta 10 | -0.0529407 |
| FTL | ferritin, light polypeptide | -0.0520787 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0510229 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.050639 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0483041 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0482775 |
| INHBA | inhibin, beta A | -0.045771 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0454587 |
| RPL35A | ribosomal protein L35a | -0.0405596 |
| RPS8 | ribosomal protein S8 | -0.0375131 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0359547 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0332264 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0322925 |
| RPS6 | ribosomal protein S6 | -0.0318657 |
| ATP13A3 | ATPase type 13A3 | -0.0317454 |
| PDE10A | phosphodiesterase 10A | -0.0313337 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0306601 |
| B2M | beta-2-microglobulin | -0.0303267 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0301647 |
| HLA-B | major histocompatibility complex, class I, B | -0.0296494 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0293887 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0292336 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0291795 |
| LOXL2 | lysyl oxidase-like 2 | -0.0288474 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0287308 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0284727 |
| CDH13 | cadherin 13 | -0.0280699 |
| RPL19 | ribosomal protein L19 | -0.0277383 |
| SMAD3 | SMAD family member 3 | -0.0275684 |
| RPL12 | ribosomal protein L12 | -0.0270654 |
| UBC | ubiquitin C | -0.0260044 |
| RASA2 | RAS p21 protein activator 2 | -0.0250068 |
| S100A9 | S100 calcium binding protein A9 | -0.0247813 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0245725 |
| S100A10 | S100 calcium binding protein A10 | -0.0243099 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0242063 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0241377 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0241301 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0232599 |
| ACTG1 | actin gamma 1 | -0.0231099 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0229997 |
| CANX | calnexin | -0.0228483 |
| RPL8 | ribosomal protein L8 | -0.022769 |
| RPL11 | ribosomal protein L11 | -0.0226702 |
| RPL23 | ribosomal protein L23 | -0.0226669 |
| RPL34 | ribosomal protein L34 | -0.0223139 |
| RPLP1 | ribosomal protein, large, P1 | -0.0221394 |
| SQSTM1 | sequestosome 1 | -0.0216655 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.021544 |
| MYO10 | myosin X | -0.021485 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0209528 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0206842 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0206501 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0204893 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0204836 |
| ASPH | aspartate beta-hydroxylase | -0.0202914 |
| PGK1 | phosphoglycerate kinase 1 | -0.0202239 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0200453 |
| USP3 | ubiquitin specific peptidase 3 | -0.0198965 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0197381 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0194888 |
| RPLP0 | ribosomal protein, large, P0 | -0.0194837 |
| ECE1 | endothelin converting enzyme 1 | -0.0194456 |
| RPS24 | ribosomal protein S24 | -0.0193714 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0193362 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0192437 |
| RPL28 | ribosomal protein L28 | -0.0192003 |
| RPS19 | ribosomal protein S19 | -0.0191663 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0190447 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0190429 |
| RPL32 | ribosomal protein L32 | -0.0187154 |
| RIGI | RNA sensor RIG-I | -0.0183329 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0183283 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0181837 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0179871 |
| RLF | rearranged L-myc fusion | -0.0177523 |
| RHEB | Ras homolog enriched in brain | -0.0177353 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0174765 |
| RRBP1 | ribosome binding protein 1 | -0.0174363 |
| RPL26 | ribosomal protein L26 | -0.0174242 |
| H1-0 | H1.0 linker histone | -0.0170807 |
| RPS20 | ribosomal protein S20 | -0.0169633 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.016959 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0169577 |
| CALU | calumenin | -0.0168576 |
| KIAA1217 | KIAA1217 | -0.0168083 |
