| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0725454 |
| GOLGA4 | golgin A4 | 0.0435213 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0355573 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0333356 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.030047 |
| HYOU1 | hypoxia up-regulated 1 | 0.0296356 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0286296 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0281229 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0244443 |
| INTS6 | integrator complex subunit 6 | 0.0243181 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0240498 |
| HM13 | histocompatibility (minor) 13 | 0.0230608 |
| VIM | vimentin | 0.0226894 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0226418 |
| OGA | O-GlcNAcase | 0.0225805 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0218346 |
| NUP58 | nucleoporin 58 | 0.0217012 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0216599 |
| RBM39 | RNA binding motif protein 39 | 0.02071 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0205977 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0198649 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.019409 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0184751 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0184595 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0183445 |
| MORF4L2 | mortality factor 4 like 2 | 0.0182346 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0181342 |
| TXNRD1 | thioredoxin reductase 1 | 0.0179774 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0179569 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0178993 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.017517 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0174886 |
| ZNF292 | zinc finger protein 292 | 0.0173795 |
| RNF145 | ring finger protein 145 | 0.0171988 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0171707 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.016991 |
| BRD2 | bromodomain containing 2 | 0.0169582 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0168865 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0167903 |
| YTHDC1 | YTH domain containing 1 | 0.0167832 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0167591 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0166623 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0164776 |
| CALR | calreticulin | 0.0161907 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0158555 |
| SUCO | SUN domain containing ossification factor | 0.0154494 |
| PGM3 | phosphoglucomutase 3 | 0.0153966 |
| PCBP2 | poly(rC) binding protein 2 | 0.0153389 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0148603 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0147524 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0147213 |
| CALU | calumenin | 0.0147014 |
| USP47 | ubiquitin specific peptidase 47 | 0.014646 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0146279 |
| ZNF638 | zinc finger protein 638 | 0.0146069 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0145186 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0144701 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.014465 |
| FN1 | fibronectin 1 | 0.014405 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0143669 |
| TFG | TRK-fused gene | 0.0143652 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0143509 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0143389 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0141667 |
| TUFT1 | tuftelin 1 | 0.0140599 |
| HELZ | helicase with zinc finger | 0.0138229 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0137921 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0137413 |
| FBXO32 | F-box protein 32 | 0.0137383 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0137105 |
| RPL3 | ribosomal protein L3 | 0.0136878 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0136439 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0135479 |
| SRP54 | signal recognition particle 54kDa | 0.0135415 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0135307 |
| PREPL | prolyl endopeptidase-like | 0.0134753 |
| DMXL2 | Dmx-like 2 | 0.0134669 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0134556 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0134304 |
| ARF4 | ADP-ribosylation factor 4 | 0.0134281 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0133836 |
| SEC24D | SEC24 family member D | 0.013247 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0132024 |
| CCNL1 | cyclin L1 | 0.012998 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0129823 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0129262 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0129076 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0128885 |
| TMEM41B | transmembrane protein 41B | 0.012871 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0128072 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0126638 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0126462 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.01255 |
| PTEN | phosphatase and tensin homolog | 0.0125406 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0125257 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0124292 |
| COPA | coatomer protein complex, subunit alpha | 0.0123815 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0122349 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0121851 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0121775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.138155 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.137426 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.135367 |
| KRT20 | keratin 20, type I | -0.126693 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.124594 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116549 |
| KRT18 | keratin 18, type I | -0.116197 |
| AHNAK | AHNAK nucleoprotein | -0.11576 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.108939 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.107185 |
| KRT8 | keratin 8, type II | -0.103287 |
| LAMA4 | laminin, alpha 4 | -0.0956799 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0940681 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0932728 |
| SMAD3 | SMAD family member 3 | -0.0915904 |
| TJP1 | tight junction protein 1 | -0.083263 |
| LYZ | lysozyme | -0.0809931 |
| ANXA2 | annexin A2 | -0.0770451 |
| EZR | ezrin | -0.0764361 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0762352 |
| KRT19 | keratin 19, type I | -0.0745264 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0734189 |
| PGK1 | phosphoglycerate kinase 1 | -0.0715827 |
| ACTN4 | actinin, alpha 4 | -0.070319 |
| TMSB10 | thymosin beta 10 | -0.0701515 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0688464 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0675602 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0650496 |
| S100A10 | S100 calcium binding protein A10 | -0.0635121 |
| TMEM123 | transmembrane protein 123 | -0.0628621 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.062013 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0600375 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0596383 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0594086 |
| PLAUR | plasminogen activator, urokinase receptor | -0.057839 |
| TRIB1 | tribbles pseudokinase 1 | -0.0554602 |
| FAT1 | FAT atypical cadherin 1 | -0.0548475 |
| MYO1E | myosin IE | -0.0541359 |
| ACTG1 | actin gamma 1 | -0.0538898 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0532357 |
| NDRG1 | N-myc downstream regulated 1 | -0.0528082 |
| MMP7 | matrix metallopeptidase 7 | -0.0526466 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0522875 |
| LMNA | lamin A/C | -0.0512496 |
| FRY | furry homolog (Drosophila) | -0.0504312 |
| ETV6 | ets variant 6 | -0.0498716 |
| JUN | jun proto-oncogene | -0.0497066 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0495176 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.04888 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0487552 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0486435 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0477951 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0476672 |
| CD2AP | CD2-associated protein | -0.0471042 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.046342 |
| S100A6 | S100 calcium binding protein A6 | -0.0449671 |
| LDHA | lactate dehydrogenase A | -0.0443977 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0437914 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0437063 |
| PTMA | prothymosin, alpha | -0.0435862 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0435448 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0434469 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0433285 |
| DIAPH2 | diaphanous-related formin 2 | -0.0430795 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0428263 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0424113 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0417233 |
| RPS6 | ribosomal protein S6 | -0.0401122 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0400084 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0399268 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0397124 |
| POF1B | premature ovarian failure, 1B | -0.0396875 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0391523 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0391374 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0390817 |
| WASF2 | WAS protein family, member 2 | -0.0386666 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0375932 |
| RPLP0 | ribosomal protein, large, P0 | -0.0375414 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0375237 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0373009 |
| RPL23 | ribosomal protein L23 | -0.0371444 |
| MYO5B | myosin VB | -0.0368791 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0367951 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0366439 |
| ITGA6 | integrin, alpha 6 | -0.0358733 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0353824 |
| PLK2 | polo-like kinase 2 | -0.0349578 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0348662 |
| EGR1 | early growth response 1 | -0.0346517 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0343774 |
| RPS19 | ribosomal protein S19 | -0.033373 |
| GSN | gelsolin | -0.0333047 |
| NTN4 | netrin 4 | -0.0331567 |
| LIMA1 | LIM domain and actin binding 1 | -0.0330512 |
| STK24 | serine/threonine kinase 24 | -0.0328988 |
| TMEM65 | transmembrane protein 65 | -0.032865 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0328408 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0327631 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0327337 |
| SDC4 | syndecan 4 | -0.0325511 |
