| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.336093 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.175184 |
| C3 | complement component 3 | 0.158484 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0977534 |
| GPC6 | glypican 6 | 0.0907569 |
| APOB | apolipoprotein B | 0.0635848 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0577034 |
| MATN3 | matrilin 3 | 0.0538718 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0537852 |
| FKBP5 | FK506 binding protein 5 | 0.0402518 |
| TNS1 | tensin 1 | 0.0399379 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0322871 |
| RPL3 | ribosomal protein L3 | 0.0320305 |
| VEGFA | vascular endothelial growth factor A | 0.031825 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0292633 |
| FGA | fibrinogen alpha chain | 0.0286834 |
| MRTFA | myocardin related transcription factor A | 0.0275109 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269821 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0262214 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0256467 |
| LAMB1 | laminin, beta 1 | 0.025554 |
| CRLS1 | cardiolipin synthase 1 | 0.0252462 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0251027 |
| FGL1 | fibrinogen-like 1 | 0.0241873 |
| KRT8 | keratin 8, type II | 0.0239414 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0228417 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0227716 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0220806 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 0.0211841 |
| BCL2L1 | BCL2-like 1 | 0.0205244 |
| FKTN | fukutin | 0.0203058 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0202947 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0197842 |
| MYO1E | myosin IE | 0.0196831 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.019256 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0192248 |
| MT1E | metallothionein 1E | 0.0191902 |
| FGG | fibrinogen gamma chain | 0.0188879 |
| IFNGR1 | interferon gamma receptor 1 | 0.0188515 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0184451 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0183964 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0182914 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0181017 |
| TF | transferrin | 0.0180617 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0178051 |
| FAT1 | FAT atypical cadherin 1 | 0.0177996 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0177889 |
| TNS3 | tensin 3 | 0.0177033 |
| SLC38A2 | solute carrier family 38, member 2 | 0.017597 |
| DIAPH1 | diaphanous-related formin 1 | 0.0175071 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0174818 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.016961 |
| POTEF | POTE ankyrin domain family, member F | 0.0168478 |
| VIL1 | villin 1 | 0.0167183 |
| BRD4 | bromodomain containing 4 | 0.0165794 |
| VCL | vinculin | 0.0165458 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0165409 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0164917 |
| PDGFC | platelet derived growth factor C | 0.0164396 |
| FHIT | fragile histidine triad | 0.0161039 |
| C1D | C1D nuclear receptor corepressor | 0.015952 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0158829 |
| RASAL2 | RAS protein activator like 2 | 0.0158611 |
| DSPP | dentin sialophosphoprotein | 0.0158272 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0158113 |
| MCL1 | myeloid cell leukemia 1 | 0.0157961 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0156962 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0155494 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.0154787 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0154003 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0153389 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0152778 |
| ECE1 | endothelin converting enzyme 1 | 0.0152308 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0151752 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0150858 |
| SKIL | SKI-like proto-oncogene | 0.0149907 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0149664 |
| ACTG1 | actin gamma 1 | 0.0148586 |
| DCDC2 | doublecortin domain containing 2 | 0.0146623 |
| SMAD3 | SMAD family member 3 | 0.0146115 |
| RAD51B | RAD51 paralog B | 0.0145677 |
| IL6ST | interleukin 6 signal transducer | 0.0144161 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0143692 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0143647 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0143439 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0142203 |
| DISC1 | disrupted in schizophrenia 1 | 0.0141946 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0141522 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0141052 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0139986 |
| NPTN | neuroplastin | 0.0139832 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0139631 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0138839 |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 | 0.013875 |
| KIF26B | kinesin family member 26B | 0.0138383 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0138072 |
| IPO7 | importin 7 | 0.0137629 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0136306 |
| NRP1 | neuropilin 1 | 0.0135208 |
| NMT2 | N-myristoyltransferase 2 | 0.0135027 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.191853 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.116547 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.115108 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0935929 |
| GPC3 | glypican 3 | -0.0903701 |
| APOA2 | apolipoprotein A-II | -0.0897889 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0869793 |
| FTL | ferritin, light polypeptide | -0.0859859 |
| RPS8 | ribosomal protein S8 | -0.0767902 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0767399 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0745654 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0741443 |
| RPLP1 | ribosomal protein, large, P1 | -0.073668 |
| RPS6 | ribosomal protein S6 | -0.069749 |
| RPL35A | ribosomal protein L35a | -0.0674157 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0632454 |
| RPS24 | ribosomal protein S24 | -0.0630367 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0629723 |
| RPS19 | ribosomal protein S19 | -0.0629553 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0629402 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0574036 |
| RPL11 | ribosomal protein L11 | -0.0550841 |
| H1-0 | H1.0 linker histone | -0.0536816 |
| RPL12 | ribosomal protein L12 | -0.053465 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0521847 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0514531 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0510796 |
| TMEM123 | transmembrane protein 123 | -0.0493761 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0487696 |
| RPS27A | ribosomal protein S27a | -0.0485072 |
| RPL37A | ribosomal protein L37a | -0.0479511 |
| SDC4 | syndecan 4 | -0.0462069 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0461063 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0450656 |
| FRMD5 | FERM domain containing 5 | -0.0449302 |
| RPL34 | ribosomal protein L34 | -0.0442774 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0440845 |
| ENO1 | enolase 1, (alpha) | -0.0437179 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0435422 |
| GNAS | GNAS complex locus | -0.0423353 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0421612 |
| RPL32 | ribosomal protein L32 | -0.0412613 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0410346 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.040968 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0408371 |
| ATXN1 | ataxin 1 | -0.04026 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0400078 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0397159 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0388698 |
| APOE | apolipoprotein E | -0.0382714 |
| RPLP0 | ribosomal protein, large, P0 | -0.0381527 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.037967 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0372972 |
| TRIM26 | tripartite motif containing 26 | -0.0370572 |
| WDR45B | WD repeat domain 45B | -0.0369072 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0368157 |
| RPS14 | ribosomal protein S14 | -0.0359009 |
| RPL19 | ribosomal protein L19 | -0.0358388 |
| RPS16 | ribosomal protein S16 | -0.0350352 |
| RPS29 | ribosomal protein S29 | -0.0349302 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0345797 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0345162 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0344049 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0341904 |
| AFDN | afadin, adherens junction formation factor | -0.0340576 |
| RPL37 | ribosomal protein L37 | -0.0338718 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0336251 |
| PTMA | prothymosin, alpha | -0.0336008 |
| JMJD1C | jumonji domain containing 1C | -0.0335656 |
| PEG3 | paternally expressed 3 | -0.0328418 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0324773 |
| RPS17 | ribosomal protein S17 | -0.0319165 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0318538 |
| GDF15 | growth differentiation factor 15 | -0.031631 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0315628 |
| DTNA | dystrobrevin, alpha | -0.031343 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0310195 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0302014 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0295869 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0293314 |
| FAM162A | family with sequence similarity 162, member A | -0.0292726 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0290946 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0290701 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0290041 |
| MT2A | metallothionein 2A | -0.0288005 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0287044 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0286425 |
| RPS12 | ribosomal protein S12 | -0.0285456 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0285135 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0283305 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0282129 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0281848 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0281814 |
| PERP | PERP, TP53 apoptosis effector | -0.0281336 |
| APOC1 | apolipoprotein C-I | -0.0281108 |
| RPS5 | ribosomal protein S5 | -0.0277852 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0277185 |
| ANKRD12 | ankyrin repeat domain 12 | -0.027572 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0274867 |
| RPL13A | ribosomal protein L13a | -0.0272664 |
