| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0961459 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0919457 |
| RPL3 | ribosomal protein L3 | 0.0826108 |
| POTEF | POTE ankyrin domain family, member F | 0.065239 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0627792 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0521154 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0505377 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0427465 |
| CALB1 | calbindin 1, 28kDa | 0.0405613 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.035146 |
| EGR1 | early growth response 1 | 0.034386 |
| RPS3 | ribosomal protein S3 | 0.0333922 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330979 |
| FAT1 | FAT atypical cadherin 1 | 0.0318483 |
| RPL21 | ribosomal protein L21 | 0.0316342 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0298962 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0276617 |
| CLDN4 | claudin 4 | 0.0271045 |
| LDHA | lactate dehydrogenase A | 0.0269744 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0266081 |
| ITGB4 | integrin, beta 4 | 0.0261172 |
| BRD2 | bromodomain containing 2 | 0.0256087 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0248195 |
| GOLGA4 | golgin A4 | 0.0246085 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0242662 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.023801 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0236319 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0230994 |
| MLEC | malectin | 0.0230254 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.022848 |
| TMF1 | TATA element modulatory factor 1 | 0.0226494 |
| PTEN | phosphatase and tensin homolog | 0.0223507 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0223101 |
| PON2 | paraoxonase 2 | 0.0222025 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0220963 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0208705 |
| RPS4X | ribosomal protein S4, X-linked | 0.0205509 |
| PKP2 | plakophilin 2 | 0.0205397 |
| RPS7 | ribosomal protein S7 | 0.0203403 |
| NUCB2 | nucleobindin 2 | 0.0197572 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0192567 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0174268 |
| RPS18 | ribosomal protein S18 | 0.0167287 |
| PGM3 | phosphoglucomutase 3 | 0.0165043 |
| BCL2L1 | BCL2-like 1 | 0.0163299 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0163081 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0161335 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0156922 |
| ENO1 | enolase 1, (alpha) | 0.0155608 |
| UBE3A | ubiquitin protein ligase E3A | 0.0153726 |
| RPS2 | ribosomal protein S2 | 0.0152481 |
| ITGA6 | integrin, alpha 6 | 0.0151937 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0151081 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0149559 |
| PNN | pinin, desmosome associated protein | 0.0145479 |
| VEGFA | vascular endothelial growth factor A | 0.0144926 |
| NKTR | natural killer cell triggering receptor | 0.0144601 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0144336 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0144133 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0143322 |
| SHROOM3 | shroom family member 3 | 0.014111 |
| SSR1 | signal sequence receptor, alpha | 0.0139861 |
| RPS12 | ribosomal protein S12 | 0.0138844 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0138671 |
| CCNL1 | cyclin L1 | 0.0138416 |
| ZFP36 | ZFP36 ring finger protein | 0.0138023 |
| MCL1 | myeloid cell leukemia 1 | 0.0135799 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0134959 |
| TNS4 | tensin 4 | 0.0134907 |
| AREG | amphiregulin | 0.0134034 |
| LRRC1 | leucine rich repeat containing 1 | 0.0133273 |
| TOP1 | topoisomerase (DNA) I | 0.013208 |
| TPM3 | tropomyosin 3 | 0.0129931 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0127479 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0126268 |
| DNM2 | dynamin 2 | 0.0124738 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.012365 |
| GDF15 | growth differentiation factor 15 | 0.0122885 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0122561 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.0122428 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0121405 |
| NRDC | nardilysin convertase | 0.0121377 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.0119644 |
| CCPG1 | cell cycle progression 1 | 0.0119332 |
| MBD6 | methyl-CpG binding domain protein 6 | 0.0119299 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0116585 |
| PKM | pyruvate kinase, muscle | 0.0116444 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0115014 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.011476 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0114752 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0113476 |
| TMEM45B | transmembrane protein 45B | 0.0113219 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0113119 |
| CLDN7 | claudin 7 | 0.0112601 |
| YBX3 | Y box binding protein 3 | 0.0111925 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.0111064 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0109886 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0109831 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.010963 |
| RPL29 | ribosomal protein L29 | 0.0109382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.216094 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.129507 |
| RPLP1 | ribosomal protein, large, P1 | -0.122209 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110604 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.110457 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0956711 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0849779 |
| PTMA | prothymosin, alpha | -0.0761132 |
| MSI2 | musashi RNA-binding protein 2 | -0.0730351 |
| RPLP0 | ribosomal protein, large, P0 | -0.0702038 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0699663 |
| RPS24 | ribosomal protein S24 | -0.0695737 |
| RPL34 | ribosomal protein L34 | -0.0681537 |
| RPS21 | ribosomal protein S21 | -0.0680025 |
| RPLP2 | ribosomal protein, large, P2 | -0.06302 |
| RPS8 | ribosomal protein S8 | -0.0623807 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0616206 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0611644 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0577753 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0540362 |
| RPL35A | ribosomal protein L35a | -0.054004 |
| RPS27A | ribosomal protein S27a | -0.0532875 |
| RPS23 | ribosomal protein S23 | -0.0531516 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0529785 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0516756 |
| RPS25 | ribosomal protein S25 | -0.0493881 |
| LMO7 | LIM domain 7 | -0.049382 |
| RPS13 | ribosomal protein S13 | -0.0482428 |
| SERINC5 | serine incorporator 5 | -0.0471245 |
| CUX1 | cut-like homeobox 1 | -0.0466263 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0462773 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.045667 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0431396 |
| RPL38 | ribosomal protein L38 | -0.0429753 |
| FRMD5 | FERM domain containing 5 | -0.0427837 |
| RPS29 | ribosomal protein S29 | -0.042201 |
| ACTG1 | actin gamma 1 | -0.0412554 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0401249 |
| SP100 | SP100 nuclear antigen | -0.0400972 |
| TCF12 | transcription factor 12 | -0.0400277 |
| RPS6 | ribosomal protein S6 | -0.0385131 |
| HLA-B | major histocompatibility complex, class I, B | -0.0382987 |
| TMSB10 | thymosin beta 10 | -0.0380533 |
| RPL8 | ribosomal protein L8 | -0.0369107 |
| RRBP1 | ribosome binding protein 1 | -0.0367269 |
| AOPEP | aminopeptidase O (putative) | -0.0364643 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0363058 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0360604 |
| LAMB3 | laminin, beta 3 | -0.0360569 |
| RPL32 | ribosomal protein L32 | -0.0359316 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0357009 |
| MX1 | MX dynamin-like GTPase 1 | -0.0354408 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0353099 |
| FOXP1 | forkhead box P1 | -0.0352617 |
| KRT18 | keratin 18, type I | -0.0351102 |
| DENND1A | DENN/MADD domain containing 1A | -0.0349689 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.034737 |
| IER3 | immediate early response 3 | -0.0342508 |
| DSG2 | desmoglein 2 | -0.0341063 |
| RPL31 | ribosomal protein L31 | -0.0338987 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0338475 |
| S100A10 | S100 calcium binding protein A10 | -0.0337186 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0336823 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0336618 |
| RPL12 | ribosomal protein L12 | -0.0336494 |
| FUS | FUS RNA binding protein | -0.0331649 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0328493 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0327552 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0325313 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0323114 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0316836 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0316414 |
| XAF1 | XIAP associated factor 1 | -0.0315398 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0313166 |
| FBXO11 | F-box protein 11 | -0.0311128 |
| FERMT1 | fermitin family member 1 | -0.0310838 |
| RIGI | RNA sensor RIG-I | -0.0310156 |
| SQSTM1 | sequestosome 1 | -0.0308332 |
| RPS16 | ribosomal protein S16 | -0.0308009 |
| RPS15 | ribosomal protein S15 | -0.030455 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0304075 |
| RPL11 | ribosomal protein L11 | -0.0304044 |
| RPL36A | ribosomal protein L36a | -0.0303619 |
| TSPAN8 | tetraspanin 8 | -0.0303355 |
| RPL19 | ribosomal protein L19 | -0.0301979 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0300435 |
| CDK6 | cyclin-dependent kinase 6 | -0.0297766 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0294385 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0293006 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0292292 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0291664 |
| RPL28 | ribosomal protein L28 | -0.0290565 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0288871 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.028846 |
| RPS11 | ribosomal protein S11 | -0.0287426 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0286162 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0285779 |
| S100A9 | S100 calcium binding protein A9 | -0.0285237 |
| RNF213 | ring finger protein 213 | -0.0283023 |
| RPL6 | ribosomal protein L6 | -0.028188 |
