| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.182622 |
| S100P | S100 calcium binding protein P | 0.118677 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0892009 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0603992 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0442467 |
| CES1 | carboxylesterase 1 | 0.039889 |
| MKI67 | marker of proliferation Ki-67 | 0.038034 |
| IRS2 | insulin receptor substrate 2 | 0.0356882 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.034997 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0346221 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0326564 |
| DSPP | dentin sialophosphoprotein | 0.031582 |
| FRY | furry homolog (Drosophila) | 0.0300605 |
| MT1X | metallothionein 1X | 0.0272983 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0266791 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0266241 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0257374 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0251987 |
| LDHA | lactate dehydrogenase A | 0.0248938 |
| AHNAK | AHNAK nucleoprotein | 0.0234692 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0231294 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0227651 |
| DNER | delta/notch-like EGF repeat containing | 0.0209511 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.020211 |
| ATP11A | ATPase, class VI, type 11A | 0.0201458 |
| PYGL | phosphorylase, glycogen, liver | 0.0193387 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0185553 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0182734 |
| EGFR | epidermal growth factor receptor | 0.0178025 |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit | 0.0177897 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0175692 |
| PLEC | plectin | 0.0175365 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0172053 |
| MLKL | mixed lineage kinase domain-like | 0.0171711 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.0167735 |
| NEBL | nebulette | 0.0161759 |
| RPL3 | ribosomal protein L3 | 0.0155677 |
| FKBP5 | FK506 binding protein 5 | 0.0151863 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0148479 |
| METTL9 | methyltransferase like 9 | 0.014747 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0146903 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0144414 |
| TPM3 | tropomyosin 3 | 0.0140883 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0139122 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0138333 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0138177 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0136633 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0135987 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0134863 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0130465 |
| CALD1 | caldesmon 1 | 0.0126896 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0124308 |
| CAPRIN2 | caprin family member 2 | 0.0124104 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0123771 |
| RBM25 | RNA binding motif protein 25 | 0.0117295 |
| MTSS1 | metastasis suppressor 1 | 0.0114403 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0110359 |
| TRIM29 | tripartite motif containing 29 | 0.0108367 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0107851 |
| RNF149 | ring finger protein 149 | 0.0107497 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0107113 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.010546 |
| UBE3A | ubiquitin protein ligase E3A | 0.010466 |
| RBM19 | RNA binding motif protein 19 | 0.0102287 |
| TNRC6A | trinucleotide repeat containing 6A | 0.010066 |
| FBXO28 | F-box protein 28 | 0.0100047 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.00999131 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.00983907 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0096227 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.00947001 |
| HOMER2 | homer scaffolding protein 2 | 0.00941851 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00938088 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00935693 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.00930791 |
| POTEF | POTE ankyrin domain family, member F | 0.00927347 |
| FAM110C | family with sequence similarity 110, member C | 0.009272 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.00926866 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.00907959 |
| HMGA2 | high mobility group AT-hook 2 | 0.00907783 |
| UBE4A | ubiquitination factor E4A | 0.00904719 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.00899507 |
| GPATCH2L | G patch domain containing 2-like | 0.00894015 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.00887443 |
| WDR41 | WD repeat domain 41 | 0.00881901 |
| ZNF292 | zinc finger protein 292 | 0.00878324 |
| AUTS2 | autism susceptibility candidate 2 | 0.00870719 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.00854066 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.00846886 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00843761 |
| LRRC8A | leucine rich repeat containing 8 family, member A | 0.00842487 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.00837337 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.00833139 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.00825964 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00824159 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.00817928 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00810642 |
| RPS4X | ribosomal protein S4, X-linked | 0.00802057 |
| PNN | pinin, desmosome associated protein | 0.00802005 |
| KRT6A | keratin 6A, type II | 0.00801644 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.00789727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.281436 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.162195 |
| ASPH | aspartate beta-hydroxylase | -0.117945 |
| TXNRD1 | thioredoxin reductase 1 | -0.0962906 |
| NDRG1 | N-myc downstream regulated 1 | -0.0800218 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0791905 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0667708 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0625736 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0620508 |
| PTMA | prothymosin, alpha | -0.0591906 |
| ACTG1 | actin gamma 1 | -0.0576273 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0557364 |
| S100A10 | S100 calcium binding protein A10 | -0.05422 |
| TMSB10 | thymosin beta 10 | -0.0533912 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0524402 |
| ANXA2 | annexin A2 | -0.0521836 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.051165 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0457046 |
| STC1 | stanniocalcin 1 | -0.0444128 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0437087 |
| FTL | ferritin, light polypeptide | -0.043366 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0429776 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0369063 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0366197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0364694 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.035176 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0349562 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0344656 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0341081 |
| LMO7 | LIM domain 7 | -0.0337096 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0331448 |
| LAMC2 | laminin, gamma 2 | -0.0330358 |
| RPS24 | ribosomal protein S24 | -0.0323537 |
| MYO1E | myosin IE | -0.0322187 |
| EGR1 | early growth response 1 | -0.0304134 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0292555 |
| UBC | ubiquitin C | -0.0287053 |
| RNF213 | ring finger protein 213 | -0.027053 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0268639 |
| PKM | pyruvate kinase, muscle | -0.0267092 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0266035 |
| RPS25 | ribosomal protein S25 | -0.0264685 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0262034 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0262011 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.02613 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0255772 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0254057 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0253488 |
| HLA-B | major histocompatibility complex, class I, B | -0.025292 |
| SMAD3 | SMAD family member 3 | -0.0252899 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0249734 |
| AREG | amphiregulin | -0.0244034 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0242179 |
| MAP7 | microtubule-associated protein 7 | -0.0242108 |
| SLC38A2 | solute carrier family 38, member 2 | -0.02393 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0237765 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0234576 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0234316 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0233818 |
| GRAMD1B | GRAM domain containing 1B | -0.0232448 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0232014 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0230334 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0227363 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0226608 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0220618 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0218437 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0218249 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0218218 |
| SP100 | SP100 nuclear antigen | -0.0217355 |
| IER3 | immediate early response 3 | -0.0217131 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0214237 |
| INTS6 | integrator complex subunit 6 | -0.0213377 |
| GRB10 | growth factor receptor-bound protein 10 | -0.021221 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0211723 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0210374 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0206405 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0206282 |
| PARD3 | par-3 family cell polarity regulator | -0.0206038 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0200349 |
| RPL35A | ribosomal protein L35a | -0.0199878 |
| ABLIM1 | actin binding LIM protein 1 | -0.0199576 |
| ANXA1 | annexin A1 | -0.0198666 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0198656 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0194767 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0194072 |
| PGK1 | phosphoglycerate kinase 1 | -0.0192477 |
| FUS | FUS RNA binding protein | -0.0191865 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0191417 |
| KRT18 | keratin 18, type I | -0.0190937 |
| FBXO11 | F-box protein 11 | -0.0190886 |
| RPL31 | ribosomal protein L31 | -0.0189229 |
| CPE | carboxypeptidase E | -0.0185618 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0183393 |
| PDE8A | phosphodiesterase 8A | -0.0181839 |
| HOMER1 | homer scaffolding protein 1 | -0.0180174 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0179425 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0178574 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0177996 |
| KRT7 | keratin 7, type II | -0.0175388 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0174934 |
