| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.10539 |
| MT2A | metallothionein 2A | 0.0797588 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0472243 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0441368 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0387645 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0336487 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0317359 |
| FGB | fibrinogen beta chain | 0.031184 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0304677 |
| WDR43 | WD repeat domain 43 | 0.0304556 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0295133 |
| SRGN | serglycin | 0.026943 |
| FGA | fibrinogen alpha chain | 0.0264774 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0261862 |
| KLF6 | Kruppel-like factor 6 | 0.0245466 |
| CENPF | centromere protein F, 350/400kDa | 0.022855 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0224271 |
| MKI67 | marker of proliferation Ki-67 | 0.0207437 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0205423 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0186576 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0182115 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0181922 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0180565 |
| RPL3 | ribosomal protein L3 | 0.0176701 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0174645 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0173449 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0170109 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0170031 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0163324 |
| TPX2 | TPX2, microtubule-associated | 0.0162988 |
| RTN4 | reticulon 4 | 0.0157909 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0156144 |
| YBX3 | Y box binding protein 3 | 0.0153145 |
| HMGB2 | high mobility group box 2 | 0.0152662 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0152453 |
| RBM27 | RNA binding motif protein 27 | 0.0150037 |
| RBM25 | RNA binding motif protein 25 | 0.0149615 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0146806 |
| SIN3A | SIN3 transcription regulator family member A | 0.0143245 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0143229 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0143118 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0143055 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0141887 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0140807 |
| CCNL1 | cyclin L1 | 0.0139913 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0139602 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0138258 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0136465 |
| LAMB1 | laminin, beta 1 | 0.0135056 |
| PKM | pyruvate kinase, muscle | 0.013315 |
| CENPE | centromere protein E, 312kDa | 0.013249 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.0130043 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0129635 |
| TFG | TRK-fused gene | 0.012879 |
| RPS7 | ribosomal protein S7 | 0.0127687 |
| RPL4 | ribosomal protein L4 | 0.0127565 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.0127397 |
| CRY1 | cryptochrome circadian clock 1 | 0.0127348 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0126009 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0124318 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0122726 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0122419 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0122417 |
| POTEF | POTE ankyrin domain family, member F | 0.0119734 |
| CAVIN2 | caveolae associated protein 2 | 0.0118508 |
| FAM135A | family with sequence similarity 135, member A | 0.0117445 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0116448 |
| KIF23 | kinesin family member 23 | 0.011551 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0115194 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0114764 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0114509 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0114296 |
| SF1 | splicing factor 1 | 0.0113226 |
| ECT2 | epithelial cell transforming 2 | 0.0113077 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.011212 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0110941 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0110839 |
| TMEM123 | transmembrane protein 123 | 0.0108807 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0108383 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0107838 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0107707 |
| PCBP2 | poly(rC) binding protein 2 | 0.0106968 |
| TPM3 | tropomyosin 3 | 0.0106018 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.010591 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0104237 |
| UBE3A | ubiquitin protein ligase E3A | 0.010382 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0102959 |
| FOXJ3 | forkhead box J3 | 0.0102715 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0102582 |
| YBX1 | Y box binding protein 1 | 0.0102368 |
| PRR11 | proline rich 11 | 0.0102245 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0101958 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0101833 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0101517 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.0101086 |
| DEK | DEK proto-oncogene | 0.0100763 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0100492 |
| GTPBP4 | GTP binding protein 4 | 0.00998264 |
| CCDC6 | coiled-coil domain containing 6 | 0.00996967 |
| WTAP | Wilms tumor 1 associated protein | 0.00981996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.248174 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.17328 |
| DOCK4 | dedicator of cytokinesis 4 | -0.121356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.114037 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0997124 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0927521 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0919228 |
| TMSB10 | thymosin beta 10 | -0.091046 |
| CMIP | c-Maf inducing protein | -0.0768398 |
| VIM | vimentin | -0.0724355 |
| FTL | ferritin, light polypeptide | -0.0710261 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0695856 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0639463 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0614622 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0589027 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0569564 |
| IER3 | immediate early response 3 | -0.052145 |
| PYGL | phosphorylase, glycogen, liver | -0.0486007 |
| FMNL2 | formin-like 2 | -0.0457894 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0443203 |
| SVIL | supervillin | -0.0439598 |
| EGFR | epidermal growth factor receptor | -0.042588 |
| FLNB | filamin B, beta | -0.0412555 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0409554 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0392263 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0382961 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0378031 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0367184 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0360613 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0357415 |
| IGF2 | insulin-like growth factor 2 | -0.0357251 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0353093 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0352539 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0349032 |
| S100A6 | S100 calcium binding protein A6 | -0.0344856 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0337965 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.033689 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0335079 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0334071 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.033089 |
| ACTG1 | actin gamma 1 | -0.0327969 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0319723 |
| ATXN1 | ataxin 1 | -0.0306473 |
| RPL19 | ribosomal protein L19 | -0.030597 |
| GLIS3 | GLIS family zinc finger 3 | -0.0305718 |
| HLA-B | major histocompatibility complex, class I, B | -0.0302707 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0301683 |
| USP34 | ubiquitin specific peptidase 34 | -0.0295729 |
| KYNU | kynureninase | -0.0293428 |
| MCL1 | myeloid cell leukemia 1 | -0.0290484 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0289393 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0287929 |
| FAM107B | family with sequence similarity 107, member B | -0.0287589 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0280879 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0279673 |
| NRG1 | neuregulin 1 | -0.0279602 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0279136 |
| NEGR1 | neuronal growth regulator 1 | -0.027562 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0274043 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0268634 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0268068 |
| AHNAK | AHNAK nucleoprotein | -0.0266325 |
| NF1 | neurofibromin 1 | -0.0265878 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0262626 |
| DST | dystonin | -0.0259091 |
| ACTN1 | actinin, alpha 1 | -0.0258249 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0257962 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0256986 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0254066 |
| ASPH | aspartate beta-hydroxylase | -0.0253488 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0251079 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0246457 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0245759 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0245175 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0241982 |
| NEBL | nebulette | -0.0241781 |
| MYOF | myoferlin | -0.0240461 |
| NUMB | numb homolog (Drosophila) | -0.0240409 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0237158 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0236277 |
| GRAMD1B | GRAM domain containing 1B | -0.0233542 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0227988 |
| ATG7 | autophagy related 7 | -0.0227211 |
| CAVIN1 | caveolae associated protein 1 | -0.0224132 |
| STC1 | stanniocalcin 1 | -0.0223926 |
| BICC1 | BicC family RNA binding protein 1 | -0.0222706 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0221587 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0218197 |
| S100A10 | S100 calcium binding protein A10 | -0.0217501 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.021599 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0213558 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0213138 |
| SMAD3 | SMAD family member 3 | -0.021283 |
| NAV3 | neuron navigator 3 | -0.0211622 |
| PARD3 | par-3 family cell polarity regulator | -0.021154 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0210422 |
| AK1 | adenylate kinase 1 | -0.0208769 |
| CUX1 | cut-like homeobox 1 | -0.0208703 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0207646 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0207446 |
