| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.0967722 |
| MT2A | metallothionein 2A | 0.0880682 |
| TMSB10 | thymosin beta 10 | 0.0815522 |
| SMAD3 | SMAD family member 3 | 0.0623128 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0588819 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0573368 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0524999 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.051588 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0501065 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0489448 |
| GPC6 | glypican 6 | 0.0487523 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0463973 |
| RPS3 | ribosomal protein S3 | 0.0461223 |
| FTL | ferritin, light polypeptide | 0.043622 |
| RPS25 | ribosomal protein S25 | 0.0429354 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0426841 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0413851 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0399189 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.039558 |
| CD109 | CD109 molecule | 0.0389988 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0385477 |
| VIM | vimentin | 0.038301 |
| TOP1 | topoisomerase (DNA) I | 0.0381953 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0376532 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.035184 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0344464 |
| AREG | amphiregulin | 0.0337207 |
| LAMA4 | laminin, alpha 4 | 0.033537 |
| PGK1 | phosphoglycerate kinase 1 | 0.0334239 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0330674 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0329112 |
| HLA-A | major histocompatibility complex, class I, A | 0.0326993 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0324309 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0319409 |
| RPL37A | ribosomal protein L37a | 0.0312934 |
| POTEF | POTE ankyrin domain family, member F | 0.0312878 |
| RASA2 | RAS p21 protein activator 2 | 0.0312322 |
| PHF21A | PHD finger protein 21A | 0.0308898 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0308049 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0307413 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0305792 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0305025 |
| EGFR | epidermal growth factor receptor | 0.029925 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.029848 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0291345 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0285178 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.02819 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0280917 |
| CD44 | CD44 molecule (Indian blood group) | 0.0280409 |
| WWC2 | WW and C2 domain containing 2 | 0.0279009 |
| FLNA | filamin A, alpha | 0.0278028 |
| YEATS2 | YEATS domain containing 2 | 0.0275393 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0274503 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0272428 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0272157 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0272057 |
| ITGB5 | integrin, beta 5 | 0.0270882 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0270723 |
| RPL23 | ribosomal protein L23 | 0.0270021 |
| RACK1 | receptor for activated C kinase 1 | 0.0269166 |
| MAP1B | microtubule-associated protein 1B | 0.0266902 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0264275 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0263276 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0262835 |
| MKI67 | marker of proliferation Ki-67 | 0.0261415 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0260552 |
| KIAA1958 | KIAA1958 | 0.0259874 |
| RBM26 | RNA binding motif protein 26 | 0.0257545 |
| METTL15 | methyltransferase like 15 | 0.025753 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0256665 |
| HELZ | helicase with zinc finger | 0.0255885 |
| IPO7 | importin 7 | 0.0255287 |
| CALR | calreticulin | 0.025472 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0253316 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.024818 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0246871 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0244464 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.024394 |
| NKTR | natural killer cell triggering receptor | 0.0241552 |
| CCNL1 | cyclin L1 | 0.0240987 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0239648 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0239257 |
| RPL3 | ribosomal protein L3 | 0.0239241 |
| RPL26 | ribosomal protein L26 | 0.0237452 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0237198 |
| BBX | bobby sox homolog (Drosophila) | 0.0236342 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0235767 |
| RPS4X | ribosomal protein S4, X-linked | 0.0235657 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0235389 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0231275 |
| SON | SON DNA binding protein | 0.0229535 |
| RPL8 | ribosomal protein L8 | 0.0228585 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0228033 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0227783 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0225733 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0221917 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0221786 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0221417 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0221174 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0219911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.210779 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.158401 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.153114 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.113624 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.111048 |
| LAMB3 | laminin, beta 3 | -0.110268 |
| ATOSA | atos homolog A | -0.0970914 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0970499 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0902109 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0830486 |
| OGA | O-GlcNAcase | -0.0753557 |
| SVIL | supervillin | -0.0655612 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0652437 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0646248 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0632276 |
| TXNRD1 | thioredoxin reductase 1 | -0.0609664 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0608385 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0586432 |
| MUC16 | mucin 16, cell surface associated | -0.058551 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0579843 |
| ABHD17C | abhydrolase domain containing 17C | -0.0568493 |
| TJP1 | tight junction protein 1 | -0.0564729 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0547696 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0545925 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0521212 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0516064 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0514486 |
| AHNAK | AHNAK nucleoprotein | -0.0502989 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.048784 |
| RBM47 | RNA binding motif protein 47 | -0.0469308 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0468903 |
| EZR | ezrin | -0.0468213 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0465879 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0463946 |
| KYNU | kynureninase | -0.0445202 |
| TXNIP | thioredoxin interacting protein | -0.0437467 |
| ZNF292 | zinc finger protein 292 | -0.0429441 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0421377 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0421018 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0419678 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0415811 |
| JMJD1C | jumonji domain containing 1C | -0.0382843 |
| MED13 | mediator complex subunit 13 | -0.0380572 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0378768 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0378557 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0376287 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0373767 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0372703 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0371332 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0369487 |
| IGF2 | insulin-like growth factor 2 | -0.0367514 |
| TCF12 | transcription factor 12 | -0.0365341 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0365113 |
| FOXO3 | forkhead box O3 | -0.0362464 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0360912 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0358858 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0353579 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0352777 |
| MYO1E | myosin IE | -0.0352192 |
| SQSTM1 | sequestosome 1 | -0.0351137 |
| FOXO1 | forkhead box O1 | -0.0349715 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0347986 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0343167 |
| FAM13A | family with sequence similarity 13, member A | -0.0341776 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0335489 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0327121 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0325341 |
| CYTH1 | cytohesin 1 | -0.0324534 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0321215 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0320613 |
| FOXP1 | forkhead box P1 | -0.0317659 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0316925 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0312837 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0312307 |
| CLMP | CXADR-like membrane protein | -0.0312069 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0311646 |
| TUSC3 | tumor suppressor candidate 3 | -0.0307438 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0305306 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0303083 |
| NPTN | neuroplastin | -0.030172 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0298232 |
| KRT7 | keratin 7, type II | -0.0293249 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0292454 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0291967 |
| NHSL1 | NHS-like 1 | -0.029065 |
| DUSP16 | dual specificity phosphatase 16 | -0.0289689 |
| NAV2 | neuron navigator 2 | -0.0284898 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0283472 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0282733 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0280271 |
| PRKCA | protein kinase C, alpha | -0.0272958 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0272064 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0270592 |
| KRT17 | keratin 17, type I | -0.0270205 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0269577 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0269224 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0269067 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.026817 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0263594 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0261422 |
