| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | 0.047914 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0330508 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0309387 |
| TXNRD1 | thioredoxin reductase 1 | 0.0280816 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.02718 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0269558 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0261536 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0254932 |
| TPM3 | tropomyosin 3 | 0.0249023 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0241711 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0219827 |
| SMC4 | structural maintenance of chromosomes 4 | 0.02068 |
| IPO7 | importin 7 | 0.0206426 |
| GRAMD1B | GRAM domain containing 1B | 0.019399 |
| CENPF | centromere protein F, 350/400kDa | 0.0188064 |
| RTN4 | reticulon 4 | 0.0182004 |
| LDHB | lactate dehydrogenase B | 0.018118 |
| RPL3 | ribosomal protein L3 | 0.0177869 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0177215 |
| GPHN | gephyrin | 0.0171291 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0170712 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.016975 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.016897 |
| MKI67 | marker of proliferation Ki-67 | 0.0168894 |
| POTEF | POTE ankyrin domain family, member F | 0.0166696 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0164919 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0161733 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0160581 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0158202 |
| WDR43 | WD repeat domain 43 | 0.0158156 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0156115 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0151602 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0148845 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0143662 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0143479 |
| MIS18BP1 | MIS18 binding protein 1 | 0.014127 |
| PNN | pinin, desmosome associated protein | 0.0140784 |
| RNF38 | ring finger protein 38 | 0.01391 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0137803 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0136989 |
| TCERG1 | transcription elongation regulator 1 | 0.0136767 |
| CENPE | centromere protein E, 312kDa | 0.0136336 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0134711 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.013441 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0132397 |
| GMPS | guanine monphosphate synthase | 0.0132393 |
| CBX3 | chromobox homolog 3 | 0.0132148 |
| PHIP | pleckstrin homology domain interacting protein | 0.0132119 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0130963 |
| DIAPH1 | diaphanous-related formin 1 | 0.0127933 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0127685 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0127376 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0125047 |
| PLCB4 | phospholipase C, beta 4 | 0.0124801 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0124504 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0124475 |
| SP3 | Sp3 transcription factor | 0.0123862 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0123807 |
| SRSF7 | serine/arginine-rich splicing factor 7 | 0.0123767 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0123443 |
| CTPS1 | CTP synthase 1 | 0.0122409 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0122392 |
| PKP4 | plakophilin 4 | 0.0120893 |
| PTEN | phosphatase and tensin homolog | 0.0120055 |
| NUP153 | nucleoporin 153kDa | 0.011968 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0117114 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0117047 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0116002 |
| BRD2 | bromodomain containing 2 | 0.0115532 |
| BRD4 | bromodomain containing 4 | 0.0114904 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.011488 |
| PFKP | phosphofructokinase, platelet | 0.011459 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0114549 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0113809 |
| SET | SET nuclear proto-oncogene | 0.0113595 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0113573 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0113485 |
| XPO1 | exportin 1 | 0.0112439 |
| NUP155 | nucleoporin 155kDa | 0.0112002 |
| CASC3 | cancer susceptibility candidate 3 | 0.0111663 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0111154 |
| PKM | pyruvate kinase, muscle | 0.0110862 |
| SMC6 | structural maintenance of chromosomes 6 | 0.0110314 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0110048 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.010793 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0107569 |
| TMPO | thymopoietin | 0.0106998 |
| PCBP2 | poly(rC) binding protein 2 | 0.0106648 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0106285 |
| ATXN2L | ataxin 2-like | 0.0105152 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.010393 |
| RASAL2 | RAS protein activator like 2 | 0.0103858 |
| HELLS | helicase, lymphoid-specific | 0.0103403 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0103063 |
| YTHDC1 | YTH domain containing 1 | 0.0102356 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0101817 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0100742 |
| GSE1 | Gse1 coiled-coil protein | 0.00995004 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00987909 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.00971264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.291635 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.139806 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.103609 |
| TMSB10 | thymosin beta 10 | -0.0887655 |
| YBX3 | Y box binding protein 3 | -0.078692 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.062628 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0616208 |
| VIM | vimentin | -0.0599248 |
| PTMA | prothymosin, alpha | -0.0591881 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0538797 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0525325 |
| OSMR | oncostatin M receptor | -0.052069 |
| HLA-B | major histocompatibility complex, class I, B | -0.0512741 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0505805 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0479161 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0475867 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0433809 |
| MCL1 | myeloid cell leukemia 1 | -0.0399234 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0395644 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0387537 |
| RPL37A | ribosomal protein L37a | -0.0382211 |
| MT2A | metallothionein 2A | -0.0376463 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0368664 |
| HMGA2 | high mobility group AT-hook 2 | -0.0367782 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.036212 |
| IGF1R | insulin-like growth factor 1 receptor | -0.035954 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0352639 |
| RPL37 | ribosomal protein L37 | -0.0347982 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0340433 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0338585 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0334759 |
| PDE10A | phosphodiesterase 10A | -0.0327377 |
| RPL26 | ribosomal protein L26 | -0.0325612 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0324354 |
| RPL12 | ribosomal protein L12 | -0.0320863 |
| TPM4 | tropomyosin 4 | -0.0315542 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0313152 |
| IER3 | immediate early response 3 | -0.0309457 |
| RAD51B | RAD51 paralog B | -0.0309341 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0308343 |
| GNAS | GNAS complex locus | -0.0301994 |
| RPL35A | ribosomal protein L35a | -0.0300481 |
| FTL | ferritin, light polypeptide | -0.0293154 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0292858 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0292014 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0291516 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.02914 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0288054 |
| FMNL2 | formin-like 2 | -0.0286542 |
| EGFR | epidermal growth factor receptor | -0.0285621 |
| STC1 | stanniocalcin 1 | -0.0283521 |
| RNF213 | ring finger protein 213 | -0.0282002 |
| RPLP1 | ribosomal protein, large, P1 | -0.0279886 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0277585 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0276178 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0275586 |
| RPL19 | ribosomal protein L19 | -0.0273688 |
| ACTG1 | actin gamma 1 | -0.0273187 |
| RPS8 | ribosomal protein S8 | -0.0269904 |
| ATXN1 | ataxin 1 | -0.0266626 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0266304 |
| RSF1 | remodeling and spacing factor 1 | -0.0265773 |
| FBXO11 | F-box protein 11 | -0.0262274 |
| EGR1 | early growth response 1 | -0.0258588 |
| ATP11A | ATPase, class VI, type 11A | -0.0255013 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0253847 |
| CANX | calnexin | -0.0252398 |
| NF1 | neurofibromin 1 | -0.0251664 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0248183 |
| RPL38 | ribosomal protein L38 | -0.0246929 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0240034 |
| PYGL | phosphorylase, glycogen, liver | -0.0239376 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0239102 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0239048 |
| PRKCE | protein kinase C, epsilon | -0.0236472 |
| S100A10 | S100 calcium binding protein A10 | -0.0236082 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0236076 |
| RPS10 | ribosomal protein S10 | -0.023567 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0235122 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0234763 |
| UBC | ubiquitin C | -0.0232091 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0230601 |
| DENND5B | DENN/MADD domain containing 5B | -0.0228234 |
| RPS27A | ribosomal protein S27a | -0.0227996 |
| RPS3 | ribosomal protein S3 | -0.0227773 |
| RYR3 | ryanodine receptor 3 | -0.0227635 |
| RPL8 | ribosomal protein L8 | -0.0226245 |
| CAVIN1 | caveolae associated protein 1 | -0.0225105 |
| RPL11 | ribosomal protein L11 | -0.0222609 |
| RPL31 | ribosomal protein L31 | -0.0221684 |
| RPS19 | ribosomal protein S19 | -0.0219739 |
| EPAS1 | endothelial PAS domain protein 1 | -0.021872 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0218646 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0218264 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.021776 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0217728 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.021688 |
| RPS21 | ribosomal protein S21 | -0.0215057 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0213716 |
| ATG7 | autophagy related 7 | -0.021228 |
