| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.245814 |
| TOP1 | topoisomerase (DNA) I | 0.139322 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.135442 |
| FN1 | fibronectin 1 | 0.131875 |
| POTEF | POTE ankyrin domain family, member F | 0.118228 |
| TMSB10 | thymosin beta 10 | 0.1077 |
| KRT7 | keratin 7, type II | 0.10195 |
| KRT8 | keratin 8, type II | 0.0972055 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0723643 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0648446 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0647444 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0643818 |
| AHNAK | AHNAK nucleoprotein | 0.0611778 |
| KRT18 | keratin 18, type I | 0.0603817 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0572771 |
| FKBP5 | FK506 binding protein 5 | 0.0560403 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0557994 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.052578 |
| ANXA2 | annexin A2 | 0.0523627 |
| HOMER2 | homer scaffolding protein 2 | 0.0512641 |
| ACTG1 | actin gamma 1 | 0.0489693 |
| LAMB3 | laminin, beta 3 | 0.0443039 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.043025 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0429084 |
| LDHA | lactate dehydrogenase A | 0.0422106 |
| KLF6 | Kruppel-like factor 6 | 0.0420554 |
| S100A6 | S100 calcium binding protein A6 | 0.0415557 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0412121 |
| CCND1 | cyclin D1 | 0.0411504 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0409533 |
| ARF1 | ADP-ribosylation factor 1 | 0.0400977 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0397466 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0389619 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0385295 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0381536 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0375689 |
| RPS4X | ribosomal protein S4, X-linked | 0.0366765 |
| RPL35A | ribosomal protein L35a | 0.0364532 |
| MT1E | metallothionein 1E | 0.0354436 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0350928 |
| IL6ST | interleukin 6 signal transducer | 0.032519 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0318339 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.031072 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0302286 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0301115 |
| AREG | amphiregulin | 0.0300862 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.029824 |
| RBM25 | RNA binding motif protein 25 | 0.0295203 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0294651 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0294141 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0292576 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0282058 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0280151 |
| RPL23 | ribosomal protein L23 | 0.0278359 |
| EGFR | epidermal growth factor receptor | 0.0274609 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0272531 |
| RASAL2 | RAS protein activator like 2 | 0.0264455 |
| VIM | vimentin | 0.0261988 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0260135 |
| PYGB | phosphorylase, glycogen; brain | 0.0256402 |
| FCHO2 | FCH domain only 2 | 0.0239836 |
| HMGA1 | high mobility group AT-hook 1 | 0.0239818 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234713 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0233142 |
| BCL2L1 | BCL2-like 1 | 0.0231838 |
| EREG | epiregulin | 0.0229505 |
| MT1X | metallothionein 1X | 0.0227711 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0227202 |
| RNF145 | ring finger protein 145 | 0.0227092 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0225256 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0221759 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0219522 |
| EDN1 | endothelin 1 | 0.0219271 |
| FLNB | filamin B, beta | 0.0218745 |
| GNAS | GNAS complex locus | 0.0217082 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0217082 |
| DUSP12 | dual specificity phosphatase 12 | 0.0217041 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0215115 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0211267 |
| COPA | coatomer protein complex, subunit alpha | 0.0210723 |
| IRS2 | insulin receptor substrate 2 | 0.0206357 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0205805 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0205004 |
| LMO7 | LIM domain 7 | 0.0204419 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0204261 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0204195 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0201944 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0201848 |
| ERBIN | erbb2 interacting protein | 0.0199609 |
| VCL | vinculin | 0.0197199 |
| HMGB2 | high mobility group box 2 | 0.0196589 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0196351 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0194825 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0194562 |
| EGR1 | early growth response 1 | 0.0194451 |
| S100A10 | S100 calcium binding protein A10 | 0.0192285 |
| TFCP2L1 | transcription factor CP2-like 1 | 0.0189256 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0189202 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0188403 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0187848 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.327472 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.218009 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171631 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.155013 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.129906 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0725931 |
| DTNA | dystrobrevin, alpha | -0.0711299 |
| SQSTM1 | sequestosome 1 | -0.0639448 |
| FAM13A | family with sequence similarity 13, member A | -0.0628634 |
| RPS2 | ribosomal protein S2 | -0.0591901 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.058496 |
| FBXO32 | F-box protein 32 | -0.0575431 |
| TXNRD1 | thioredoxin reductase 1 | -0.0557986 |
| GOLGA4 | golgin A4 | -0.0553086 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0552494 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0549732 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0536119 |
| UPP1 | uridine phosphorylase 1 | -0.0529618 |
| ASPH | aspartate beta-hydroxylase | -0.052652 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0520393 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0512218 |
| ARRDC3 | arrestin domain containing 3 | -0.0489409 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0488683 |
| LAMC2 | laminin, gamma 2 | -0.0485257 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0470525 |
| TMSB4X | thymosin beta 4, X-linked | -0.0443681 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.043981 |
| RPS6 | ribosomal protein S6 | -0.0434319 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0428397 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0422811 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0410309 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0402251 |
| NAV2 | neuron navigator 2 | -0.0395314 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0381713 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0377784 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0377141 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0376873 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.036975 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0354536 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0353921 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0349837 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0341179 |
| DUSP10 | dual specificity phosphatase 10 | -0.0338082 |
| RPL7 | ribosomal protein L7 | -0.033648 |
| PTMA | prothymosin, alpha | -0.0329692 |
| FAM3C | family with sequence similarity 3, member C | -0.0328297 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0328228 |
| MYO6 | myosin VI | -0.03267 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0325477 |
| TMF1 | TATA element modulatory factor 1 | -0.0324689 |
| MYO5B | myosin VB | -0.0319799 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0319493 |
| MXD1 | MAX dimerization protein 1 | -0.0319386 |
| SPAG9 | sperm associated antigen 9 | -0.0316739 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0314697 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0310062 |
| PAPOLA | poly(A) polymerase alpha | -0.0305065 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0303587 |
| CPNE8 | copine VIII | -0.0302218 |
| SMAD3 | SMAD family member 3 | -0.0297622 |
| RPS12 | ribosomal protein S12 | -0.0294532 |
| UBC | ubiquitin C | -0.0290176 |
| RPL32 | ribosomal protein L32 | -0.0286967 |
| RPL38 | ribosomal protein L38 | -0.0282902 |
| RYBP | RING1 and YY1 binding protein | -0.0281019 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0279532 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0278516 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0277953 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0276372 |
| H1-4 | H1.4 linker histone, cluster member | -0.0275602 |
| ZNF292 | zinc finger protein 292 | -0.0275023 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0274932 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0271165 |
| FTL | ferritin, light polypeptide | -0.026899 |
| PTK2 | protein tyrosine kinase 2 | -0.026817 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0267341 |
| RPLP2 | ribosomal protein, large, P2 | -0.0264647 |
| MKI67 | marker of proliferation Ki-67 | -0.0263667 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.026037 |
| DUSP5 | dual specificity phosphatase 5 | -0.0259736 |
| ANO6 | anoctamin 6 | -0.025964 |
| BRD2 | bromodomain containing 2 | -0.0258986 |
| PGK1 | phosphoglycerate kinase 1 | -0.0256615 |
| ANLN | anillin, actin binding protein | -0.0254281 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0253785 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0253747 |
| RPS23 | ribosomal protein S23 | -0.0253584 |
| RPS13 | ribosomal protein S13 | -0.0253212 |
| CSTB | cystatin B (stefin B) | -0.0251245 |
| TPM3 | tropomyosin 3 | -0.0250419 |
| SLMAP | sarcolemma associated protein | -0.0245561 |
| KIAA1217 | KIAA1217 | -0.0242149 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0241587 |
| RPL37A | ribosomal protein L37a | -0.0237905 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0235873 |
| RPS29 | ribosomal protein S29 | -0.023516 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0234404 |
| FAM162A | family with sequence similarity 162, member A | -0.0233999 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0233336 |
| CENPF | centromere protein F, 350/400kDa | -0.0232796 |
