| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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129 genes differentially expressed following the Betamethasone dipropionate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.225506 |
| FN1 | fibronectin 1 | 0.201713 |
| DST | dystonin | 0.116525 |
| SEPTIN9 | septin 9 | 0.0903042 |
| FMN1 | formin 1 | 0.0753632 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0749058 |
| MSN | moesin | 0.0747823 |
| SPAG9 | sperm associated antigen 9 | 0.0739983 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0738645 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0686485 |
| LOXL2 | lysyl oxidase-like 2 | 0.0673374 |
| TPM3 | tropomyosin 3 | 0.0655436 |
| POTEF | POTE ankyrin domain family, member F | 0.0651406 |
| RIGI | RNA sensor RIG-I | 0.0639792 |
| B2M | beta-2-microglobulin | 0.0635427 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0617386 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0614232 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0609544 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0570734 |
| GOLGA4 | golgin A4 | 0.056961 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0558857 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0557922 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0557817 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0552702 |
| SBF2 | SET binding factor 2 | 0.0539378 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0533598 |
| MT2A | metallothionein 2A | 0.0503628 |
| TXNIP | thioredoxin interacting protein | 0.0471621 |
| CCNL1 | cyclin L1 | 0.0462597 |
| FHIT | fragile histidine triad | 0.044457 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0424324 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0416027 |
| GPC6 | glypican 6 | 0.0401712 |
| ACTN4 | actinin, alpha 4 | 0.0401332 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0400624 |
| PGK1 | phosphoglycerate kinase 1 | 0.0394869 |
| PDE10A | phosphodiesterase 10A | 0.0393086 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0381959 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0371891 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0356265 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0355429 |
| ENO1 | enolase 1, (alpha) | 0.0333139 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0330546 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0319012 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0318233 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0312528 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0282868 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0265458 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0262174 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0250685 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0248953 |
| SETD5 | SET domain containing 5 | 0.0237057 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0198663 |
| SQSTM1 | sequestosome 1 | 0.0195945 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0167692 |
| MEF2A | myocyte enhancer factor 2A | 0.015291 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0138002 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00964069 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.00943011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00730379 |
| SRPK2 | SRSF protein kinase 2 | 0.00532032 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0049072 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.00367545 |
| LDHA | lactate dehydrogenase A | 0.00205582 |
| TMSB10 | thymosin beta 10 | 7.7236E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.302015 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.167956 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.134546 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.134372 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.115881 |
| EFNA5 | ephrin-A5 | -0.108465 |
| MYO1E | myosin IE | -0.106818 |
| HMGA2 | high mobility group AT-hook 2 | -0.100771 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.100267 |
| CANX | calnexin | -0.0982632 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0953031 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0912502 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0901955 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0878143 |
| ANXA2 | annexin A2 | -0.0851642 |
| RPS6 | ribosomal protein S6 | -0.0850714 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0836668 |
| NDRG1 | N-myc downstream regulated 1 | -0.0831454 |
| EGFR | epidermal growth factor receptor | -0.0739236 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0708935 |
| ACTG1 | actin gamma 1 | -0.0688347 |
| PTK2 | protein tyrosine kinase 2 | -0.0684789 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0649267 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0644454 |
| PRKCA | protein kinase C, alpha | -0.0634345 |
| ASPH | aspartate beta-hydroxylase | -0.0630989 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0595898 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.059281 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0589162 |
| MYOF | myoferlin | -0.0565123 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0550786 |
| PTMA | prothymosin, alpha | -0.0520651 |
| FLNB | filamin B, beta | -0.0504416 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0494291 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0442864 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0403896 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0400865 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0395722 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0348043 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0342384 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0319627 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0313013 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0311545 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0297483 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0291545 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0268969 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0262241 |
| PRELID2 | PRELI domain containing 2 | -0.0257301 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0249402 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0245177 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0232493 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0207244 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0202079 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0198753 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0163466 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0148764 |
| OGA | O-GlcNAcase | -0.0119737 |
| RTN4 | reticulon 4 | -0.0109813 |
| VIM | vimentin | -0.00946334 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.00814561 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.00794132 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.00686828 |
| LMO7 | LIM domain 7 | -0.00527638 |
| PARD3 | par-3 family cell polarity regulator | -2.15875E-4 |
