| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.111211 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0723524 |
| POTEF | POTE ankyrin domain family, member F | 0.0680688 |
| HDAC9 | histone deacetylase 9 | 0.0610242 |
| HMGB2 | high mobility group box 2 | 0.0600946 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0599334 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0569275 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.054792 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0521435 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0458003 |
| RASAL2 | RAS protein activator like 2 | 0.0428322 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0424513 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0402368 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.038861 |
| PEG10 | paternally expressed 10 | 0.0387008 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0371731 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0369363 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0361285 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0359737 |
| CENPF | centromere protein F, 350/400kDa | 0.0356234 |
| FIGN | fidgetin | 0.0345318 |
| TPX2 | TPX2, microtubule-associated | 0.0345258 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0336498 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0331878 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0322538 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0302044 |
| SCFD1 | sec1 family domain containing 1 | 0.0295582 |
| TPM3 | tropomyosin 3 | 0.0287848 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0283082 |
| TMSB10 | thymosin beta 10 | 0.0274556 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0271878 |
| RPL3 | ribosomal protein L3 | 0.0264228 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0261054 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0257154 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0254088 |
| SUGT1 | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | 0.0250521 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0247176 |
| DST | dystonin | 0.0246704 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0244564 |
| FAM171B | family with sequence similarity 171, member B | 0.024355 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0241964 |
| SRP54 | signal recognition particle 54kDa | 0.0239041 |
| CDYL | chromodomain protein, Y-like | 0.0235947 |
| MKI67 | marker of proliferation Ki-67 | 0.0234671 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 0.0232137 |
| PDCD5 | programmed cell death 5 | 0.0231126 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0224042 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0223086 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0222887 |
| RPS4X | ribosomal protein S4, X-linked | 0.0221497 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0218731 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0217757 |
| B2M | beta-2-microglobulin | 0.0212568 |
| PM20D1 | peptidase M20 domain containing 1 | 0.021179 |
| ZNF217 | zinc finger protein 217 | 0.0210935 |
| TRERF1 | transcriptional regulating factor 1 | 0.02056 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0205292 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0204724 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0204349 |
| KIF4A | kinesin family member 4A | 0.0204245 |
| CEP192 | centrosomal protein 192kDa | 0.0202125 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0201646 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0200359 |
| ZNF608 | zinc finger protein 608 | 0.0198734 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0198303 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.019818 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0197778 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0197622 |
| UTRN | utrophin | 0.0197067 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0196688 |
| CD46 | CD46 molecule, complement regulatory protein | 0.019641 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0195889 |
| RPS2 | ribosomal protein S2 | 0.0193916 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0193746 |
| PLCB4 | phospholipase C, beta 4 | 0.0193643 |
| RPS3 | ribosomal protein S3 | 0.0192968 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0190162 |
| CCDC88A | coiled-coil domain containing 88A | 0.0189464 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0189381 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0188882 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0187454 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0186521 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0184166 |
| RPL31 | ribosomal protein L31 | 0.0184061 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0182357 |
| GPC4 | glypican 4 | 0.0181912 |
| CDC27 | cell division cycle 27 | 0.018169 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0180852 |
| RBM26 | RNA binding motif protein 26 | 0.0180754 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0180383 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0179376 |
| MB21D2 | Mab-21 domain containing 2 | 0.0178225 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.0177971 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0177778 |
| KNL1 | kinetochore scaffold 1 | 0.0175886 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.017456 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0174319 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0174316 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0173454 |
| MFSD14A | major facilitator superfamily domain containing 14A | 0.0173431 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.158489 |
| COL11A1 | collagen, type XI, alpha 1 | -0.127089 |
| PCDH9 | protocadherin 9 | -0.114347 |
| COL5A2 | collagen, type V, alpha 2 | -0.0950101 |
| VIM | vimentin | -0.0937283 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0927595 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0865228 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0844819 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0724294 |
| ITGAV | integrin, alpha V | -0.0688253 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0658669 |
| PHIP | pleckstrin homology domain interacting protein | -0.0600236 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0571665 |
| COL1A2 | collagen, type I, alpha 2 | -0.051559 |
| RPS6 | ribosomal protein S6 | -0.0499759 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0498462 |
| PGK1 | phosphoglycerate kinase 1 | -0.0497771 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0496916 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0467947 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0466098 |
| RPS8 | ribosomal protein S8 | -0.0463792 |
| H1-0 | H1.0 linker histone | -0.0462773 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0461431 |
| CADM2 | cell adhesion molecule 2 | -0.045364 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0449581 |
| RAD51B | RAD51 paralog B | -0.0448014 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0446447 |
| GPC3 | glypican 3 | -0.0436279 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0413379 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0403435 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0398252 |
| AHNAK | AHNAK nucleoprotein | -0.0390342 |
| TENM3 | teneurin transmembrane protein 3 | -0.0387681 |
| ENO1 | enolase 1, (alpha) | -0.0381118 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0371892 |
| WASF2 | WAS protein family, member 2 | -0.0366958 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0366541 |
| RNF213 | ring finger protein 213 | -0.0363809 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0361034 |
| RLF | rearranged L-myc fusion | -0.0359561 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.035934 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0355027 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0342797 |
| TXNRD1 | thioredoxin reductase 1 | -0.0340262 |
| SNX6 | sorting nexin 6 | -0.0338768 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0332993 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0325089 |
| RPS16 | ribosomal protein S16 | -0.0320551 |
| TCF12 | transcription factor 12 | -0.0319192 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0311611 |
| EAPP | E2F-associated phosphoprotein | -0.0299723 |
| NCAM2 | neural cell adhesion molecule 2 | -0.029507 |
| URI1 | URI1, prefoldin-like chaperone | -0.0294272 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0288135 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.028489 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0283305 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0280307 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0280084 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0278535 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0277069 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0277054 |
| JMJD1C | jumonji domain containing 1C | -0.0276685 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0271809 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0268183 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0263707 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0261264 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0259011 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0258857 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0256159 |
| SETD5 | SET domain containing 5 | -0.0250765 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0250593 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0249447 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0249145 |
| RPL34 | ribosomal protein L34 | -0.0249124 |
| KMT5B | lysine methyltransferase 5B | -0.0248112 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0243758 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0241596 |
| HMCN1 | hemicentin 1 | -0.0241339 |
| NF1 | neurofibromin 1 | -0.0241012 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0240779 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0239679 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0238681 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0238098 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0238013 |
| NDRG1 | N-myc downstream regulated 1 | -0.0236841 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.02329 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0232464 |
| MYOF | myoferlin | -0.0230183 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0228373 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0228013 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0227801 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0227406 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0226772 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0226643 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0226269 |
| CUX1 | cut-like homeobox 1 | -0.0225671 |
| DENND5B | DENN/MADD domain containing 5B | -0.0224329 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0224085 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0223837 |
| SAMD11 | sterile alpha motif domain containing 11 | -0.0221097 |
