| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.18174 |
| FN1 | fibronectin 1 | 0.163979 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.109776 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0704163 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0691308 |
| HMGA2 | high mobility group AT-hook 2 | 0.0527351 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0428738 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0418864 |
| NAV2 | neuron navigator 2 | 0.0367469 |
| TOP1 | topoisomerase (DNA) I | 0.0366568 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0360959 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0356977 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0341772 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.032199 |
| MT1E | metallothionein 1E | 0.0299592 |
| ANGPTL4 | angiopoietin-like 4 | 0.0298942 |
| FAM13A | family with sequence similarity 13, member A | 0.0291867 |
| MYO1B | myosin IB | 0.029125 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0266975 |
| LAMB1 | laminin, beta 1 | 0.0263493 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0259368 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0254516 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0239709 |
| HIP1 | huntingtin interacting protein 1 | 0.0239571 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.021219 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0211062 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0209712 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0205514 |
| CALD1 | caldesmon 1 | 0.0187366 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0183112 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0179138 |
| MSN | moesin | 0.0163056 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0157809 |
| PCBP3 | poly(rC) binding protein 3 | 0.0155435 |
| JPH2 | junctophilin 2 | 0.0155285 |
| DNER | delta/notch-like EGF repeat containing | 0.0151887 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0149376 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.014908 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.014513 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0144341 |
| MT1X | metallothionein 1X | 0.014116 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0138527 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0137708 |
| KLF9 | Kruppel-like factor 9 | 0.0134821 |
| FOXO3 | forkhead box O3 | 0.0134677 |
| LOX | lysyl oxidase | 0.0132227 |
| CCN4 | cellular communication network factor 4 | 0.012965 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0127158 |
| POTEF | POTE ankyrin domain family, member F | 0.0125707 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0122527 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0121613 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0120773 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0120411 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0119272 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0116724 |
| PLIN2 | perilipin 2 | 0.0112553 |
| FKBP5 | FK506 binding protein 5 | 0.0112427 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0112349 |
| FOXO1 | forkhead box O1 | 0.011069 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0106811 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.0106606 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.0105787 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0105146 |
| CD109 | CD109 molecule | 0.0104153 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0103492 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0102234 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0101635 |
| FMN1 | formin 1 | 0.0101472 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00967184 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | 0.00953352 |
| BCL2L1 | BCL2-like 1 | 0.0094865 |
| LDHA | lactate dehydrogenase A | 0.00912283 |
| IRS2 | insulin receptor substrate 2 | 0.0090109 |
| CHN1 | chimerin 1 | 0.00883923 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0087375 |
| GYS1 | glycogen synthase 1 (muscle) | 0.00868412 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00866843 |
| DENND3 | DENN/MADD domain containing 3 | 0.00832672 |
| VEGFA | vascular endothelial growth factor A | 0.0083142 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00817943 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 0.00799593 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00790139 |
| DCN | decorin | 0.00770291 |
| KLF6 | Kruppel-like factor 6 | 0.00757079 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00755783 |
| ZNF608 | zinc finger protein 608 | 0.00748244 |
| TRAM2 | translocation associated membrane protein 2 | 0.0074614 |
| ZFHX3 | zinc finger homeobox 3 | 0.00728534 |
| CCND3 | cyclin D3 | 0.00725125 |
| RPS4X | ribosomal protein S4, X-linked | 0.00721777 |
| SSR1 | signal sequence receptor, alpha | 0.00709914 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.00704074 |
| TES | testin LIM domain protein | 0.00691322 |
| TOX2 | TOX high mobility group box family member 2 | 0.00691321 |
| RPL3 | ribosomal protein L3 | 0.00687605 |
| YEATS2 | YEATS domain containing 2 | 0.0068404 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00673068 |
| COL4A1 | collagen, type IV, alpha 1 | 0.00669308 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0066744 |
| GLUL | glutamate-ammonia ligase | 0.0064351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.196565 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.186728 |
| STC1 | stanniocalcin 1 | -0.0925629 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0840105 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0729216 |
| CD44 | CD44 molecule (Indian blood group) | -0.0699614 |
| NDRG1 | N-myc downstream regulated 1 | -0.0691662 |
| B2M | beta-2-microglobulin | -0.0683589 |
| COL1A2 | collagen, type I, alpha 2 | -0.0661966 |
| HLA-B | major histocompatibility complex, class I, B | -0.0607223 |
| FRMD4A | FERM domain containing 4A | -0.0561598 |
| UBC | ubiquitin C | -0.0554075 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0496576 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0495936 |
| COL1A1 | collagen, type I, alpha 1 | -0.048371 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0463586 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0453027 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0436999 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0370682 |
| FNDC3B | fibronectin type III domain containing 3B | -0.033317 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0332455 |
| FTL | ferritin, light polypeptide | -0.0331214 |
| ENO1 | enolase 1, (alpha) | -0.0316965 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0312218 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.030572 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0304676 |
| INHBA | inhibin, beta A | -0.0301223 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0296408 |
| ASPH | aspartate beta-hydroxylase | -0.0295182 |
| IER3 | immediate early response 3 | -0.0292911 |
| RPS27A | ribosomal protein S27a | -0.0292736 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0289255 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0286268 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0285666 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0284519 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0283531 |
| CALU | calumenin | -0.0282881 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0281453 |
| TPM1 | tropomyosin 1 (alpha) | -0.0281066 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0273619 |
| LOXL2 | lysyl oxidase-like 2 | -0.0271472 |
| SMAD3 | SMAD family member 3 | -0.0269121 |
| CALR | calreticulin | -0.0268538 |
| TMSB10 | thymosin beta 10 | -0.0265704 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0264744 |
| IL1B | interleukin 1, beta | -0.0262198 |
| PTMA | prothymosin, alpha | -0.0252482 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0249785 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0246209 |
| NAV1 | neuron navigator 1 | -0.0241349 |
| RUNX1 | runt-related transcription factor 1 | -0.0237096 |
| CLIC4 | chloride intracellular channel 4 | -0.02327 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0231971 |
| GOLGA4 | golgin A4 | -0.0222217 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0222038 |
| TMEM178B | transmembrane protein 178B | -0.0219394 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0219117 |
| HDAC9 | histone deacetylase 9 | -0.0218086 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0216951 |
| CDCP1 | CUB domain containing protein 1 | -0.0216615 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0214033 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.021359 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0209714 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0209549 |
| PGK1 | phosphoglycerate kinase 1 | -0.0206053 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0205423 |
| SP100 | SP100 nuclear antigen | -0.0203567 |
| HLA-A | major histocompatibility complex, class I, A | -0.0203149 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0202841 |
| ANXA2 | annexin A2 | -0.0202776 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.020224 |
| CDH13 | cadherin 13 | -0.0200942 |
| AFAP1 | actin filament associated protein 1 | -0.0200871 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0199907 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0198317 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0196163 |
| PTK2 | protein tyrosine kinase 2 | -0.0195895 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0195852 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0193978 |
| FAM20C | family with sequence similarity 20, member C | -0.0193938 |
| FAM107B | family with sequence similarity 107, member B | -0.0192992 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0189857 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0187205 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0186383 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.018391 |
| NRP1 | neuropilin 1 | -0.0181119 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0179152 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.017848 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0177212 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0175546 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0175413 |
| ACTN4 | actinin, alpha 4 | -0.017507 |
| TNNC1 | troponin C type 1 (slow) | -0.0172705 |
| CANX | calnexin | -0.0171346 |
| JUN | jun proto-oncogene | -0.017024 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0169171 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0167623 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0166599 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0166382 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0165953 |
