| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0906444 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0804114 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0682012 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.065331 |
| GPC5 | glypican 5 | 0.0616583 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0594726 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0567574 |
| CHGB | chromogranin B | 0.0550079 |
| NCKAP5 | NCK-associated protein 5 | 0.0540397 |
| SCG2 | secretogranin II | 0.0506069 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.048349 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0462891 |
| ENO1 | enolase 1, (alpha) | 0.0456857 |
| SMYD3 | SET and MYND domain containing 3 | 0.044532 |
| PEG10 | paternally expressed 10 | 0.0444726 |
| RASD1 | RAS, dexamethasone-induced 1 | 0.0442749 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0428982 |
| KIF26B | kinesin family member 26B | 0.041361 |
| NRG1 | neuregulin 1 | 0.0412456 |
| MT2A | metallothionein 2A | 0.0392113 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0387799 |
| HMGB3 | high mobility group box 3 | 0.0377128 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0372172 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0368646 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0365476 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0365329 |
| MAP1B | microtubule-associated protein 1B | 0.0359169 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0352653 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0349354 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0328164 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0326368 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0316025 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0305109 |
| NTS | neurotensin | 0.0303847 |
| PTCHD4 | patched domain containing 4 | 0.0303554 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0297532 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0296816 |
| STC1 | stanniocalcin 1 | 0.0292753 |
| NAV2 | neuron navigator 2 | 0.0287405 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0282493 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0281564 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.027628 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0275042 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0273098 |
| MYT1L | myelin transcription factor 1-like | 0.0271653 |
| TOX | thymocyte selection-associated high mobility group box | 0.0266135 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0265936 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | 0.0262427 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0262209 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0260953 |
| NBEA | neurobeachin | 0.0260904 |
| FGF14 | fibroblast growth factor 14 | 0.0255894 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0254697 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.025402 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.025259 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0247765 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0247622 |
| KCTD8 | potassium channel tetramerization domain containing 8 | 0.024646 |
| H1-0 | H1.0 linker histone | 0.0243648 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.0242345 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0241313 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.024104 |
| RNF144A | ring finger protein 144A | 0.0239306 |
| TRIM44 | tripartite motif containing 44 | 0.0237649 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0236154 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.0219738 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0218298 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0217981 |
| AOPEP | aminopeptidase O (putative) | 0.0216838 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0214447 |
| MX2 | MX dynamin-like GTPase 2 | 0.0213313 |
| LOX | lysyl oxidase | 0.0211519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0210836 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0207885 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 0.0205597 |
| NELL1 | NEL-like 1 (chicken) | 0.0204405 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.019866 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0196363 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 0.0192618 |
| ZNF804A | zinc finger protein 804A | 0.0190292 |
| GRAMD4 | GRAM domain containing 4 | 0.0189539 |
| FMN1 | formin 1 | 0.018709 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.0186536 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0185736 |
| DISC1 | disrupted in schizophrenia 1 | 0.0185325 |
| KIAA0825 | KIAA0825 | 0.0183022 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0182108 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0181977 |
| PAEP | progestagen-associated endometrial protein | 0.0180174 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.0179654 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.017788 |
| NEBL | nebulette | 0.0174841 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0174487 |
| CEP350 | centrosomal protein 350kDa | 0.0173216 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0172658 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0170324 |
| MCL1 | myeloid cell leukemia 1 | 0.0169393 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0168449 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0167893 |
| DNER | delta/notch-like EGF repeat containing | 0.0166603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.082354 |
| TENM1 | teneurin transmembrane protein 1 | -0.0704678 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0556891 |
| FTL | ferritin, light polypeptide | -0.0436387 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0425013 |
| ZNF292 | zinc finger protein 292 | -0.0423076 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0404355 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0404225 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0393395 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0371944 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0370133 |
| XPO1 | exportin 1 | -0.0368117 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0306519 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0291004 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0289258 |
| MED13L | mediator complex subunit 13-like | -0.0284956 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0283469 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0281473 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0277012 |
| DTNA | dystrobrevin, alpha | -0.0270365 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0262239 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0261182 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0260473 |
| FUS | FUS RNA binding protein | -0.0259582 |
| RPL37A | ribosomal protein L37a | -0.0248927 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0248149 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0242805 |
| RPS8 | ribosomal protein S8 | -0.0239123 |
| TUBA1B | tubulin, alpha 1b | -0.0238711 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0235965 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0233422 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0231199 |
| RPL5 | ribosomal protein L5 | -0.0230841 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0229012 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0227835 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0223832 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0220123 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0219054 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0214714 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0214312 |
| RPLP0 | ribosomal protein, large, P0 | -0.0213869 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0211923 |
| PCBP2 | poly(rC) binding protein 2 | -0.020992 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0209165 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0206113 |
| WAC | WW domain containing adaptor with coiled-coil | -0.020345 |
| TPR | translocated promoter region, nuclear basket protein | -0.0203343 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0199971 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0198306 |
| PHIP | pleckstrin homology domain interacting protein | -0.0197248 |
| SMC4 | structural maintenance of chromosomes 4 | -0.019681 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0196593 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0195984 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0195738 |
| OGA | O-GlcNAcase | -0.019537 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.019485 |
| RPS6 | ribosomal protein S6 | -0.0191723 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0191398 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.018889 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0188734 |
| B2M | beta-2-microglobulin | -0.0188664 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0188145 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | -0.0187039 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0186552 |
| PDE8A | phosphodiesterase 8A | -0.0186472 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0186433 |
| FOXC1 | forkhead box C1 | -0.0184911 |
| CDK8 | cyclin-dependent kinase 8 | -0.0184732 |
| ETV1 | ets variant 1 | -0.0184421 |
| CCNY | cyclin Y | -0.0182562 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0180697 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.0180587 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0178102 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0177802 |
| UBB | ubiquitin B | -0.0177597 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0177175 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0176177 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0175992 |
| NEMF | nuclear export mediator factor | -0.0173951 |
| SQSTM1 | sequestosome 1 | -0.0172751 |
| RPL11 | ribosomal protein L11 | -0.0172315 |
| GOLGA4 | golgin A4 | -0.0172067 |
| MATR3 | matrin 3 | -0.0171805 |
| YBX1 | Y box binding protein 1 | -0.0171788 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0171152 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0170727 |
| RPS27A | ribosomal protein S27a | -0.0169595 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0168238 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.016666 |
| TKT | transketolase | -0.0165862 |
| FMNL2 | formin-like 2 | -0.0165469 |
| RPS29 | ribosomal protein S29 | -0.0164491 |
| SRP54 | signal recognition particle 54kDa | -0.0164234 |
| WDR45B | WD repeat domain 45B | -0.0164069 |
| EFNA5 | ephrin-A5 | -0.0163777 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0163607 |
| RHEB | Ras homolog enriched in brain | -0.0163533 |
| ENAH | enabled homolog (Drosophila) | -0.0163109 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0162896 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0162874 |
