| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.173525 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.173136 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0953133 |
| TXNRD1 | thioredoxin reductase 1 | 0.0713698 |
| VIM | vimentin | 0.0660107 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0548905 |
| GOLGA4 | golgin A4 | 0.0491827 |
| KAZN | kazrin, periplakin interacting protein | 0.0484565 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0477437 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0463115 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044933 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0448733 |
| SQSTM1 | sequestosome 1 | 0.0444347 |
| FN1 | fibronectin 1 | 0.0425858 |
| RTN4 | reticulon 4 | 0.0409707 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0357309 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0345674 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0339019 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0335995 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0331942 |
| CALD1 | caldesmon 1 | 0.0331598 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0330898 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0330466 |
| CANX | calnexin | 0.0323398 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0318343 |
| MSN | moesin | 0.0312766 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.029931 |
| RAB7A | RAB7A, member RAS oncogene family | 0.029115 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0290405 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0274948 |
| PLAT | plasminogen activator, tissue | 0.0274548 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0265913 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0265691 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0260625 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0251156 |
| PKM | pyruvate kinase, muscle | 0.0249386 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0244853 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0244279 |
| FOXO3 | forkhead box O3 | 0.0238641 |
| OXSR1 | oxidative stress responsive 1 | 0.0235921 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230582 |
| ANXA5 | annexin A5 | 0.0230049 |
| LDHA | lactate dehydrogenase A | 0.0228531 |
| TNPO1 | transportin 1 | 0.0227807 |
| THOC2 | THO complex 2 | 0.0221994 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0217238 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0213883 |
| SFTPA2 | surfactant protein A2 | 0.0213574 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0212872 |
| FAM13B | family with sequence similarity 13, member B | 0.0212708 |
| SET | SET nuclear proto-oncogene | 0.0211393 |
| CDK6 | cyclin-dependent kinase 6 | 0.0211003 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0209153 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0208956 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.020766 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0205839 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0204846 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0203716 |
| FSTL5 | follistatin-like 5 | 0.0201076 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0198233 |
| ABI1 | abl-interactor 1 | 0.0197643 |
| ANXA2 | annexin A2 | 0.0197304 |
| ATP13A3 | ATPase type 13A3 | 0.0194913 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.019467 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0192492 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0190999 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0189086 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0188016 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0188 |
| IL6ST | interleukin 6 signal transducer | 0.0186629 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0186564 |
| POTEF | POTE ankyrin domain family, member F | 0.0184506 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0184025 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0183807 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0182527 |
| PMEL | premelanosome protein | 0.018239 |
| GOLGB1 | golgin B1 | 0.0181746 |
| ERBIN | erbb2 interacting protein | 0.0181725 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0181554 |
| GRAMD1B | GRAM domain containing 1B | 0.0180796 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0179734 |
| ARMC8 | armadillo repeat containing 8 | 0.0179719 |
| NAV2 | neuron navigator 2 | 0.0178872 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0178561 |
| MAX | MYC associated factor X | 0.0177643 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0177333 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | 0.0177003 |
| RNF145 | ring finger protein 145 | 0.0176747 |
| PGK1 | phosphoglycerate kinase 1 | 0.0176702 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | 0.0176444 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0173231 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0170162 |
| ACTG1 | actin gamma 1 | 0.0170151 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0169225 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.016917 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0168926 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.01689 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0167929 |
| ATRN | attractin | 0.0166953 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0166422 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.206324 |
| MT2A | metallothionein 2A | -0.186943 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.102254 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0708415 |
| LSAMP | limbic system-associated membrane protein | -0.0683333 |
| NRG3 | neuregulin 3 | -0.0682174 |
| RAD51B | RAD51 paralog B | -0.0496417 |
| TMSB10 | thymosin beta 10 | -0.0456594 |
| PTK2 | protein tyrosine kinase 2 | -0.0428374 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0400775 |
| CFAP20DC | CFAP20 domain containing | -0.0385661 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0376825 |
| FMNL2 | formin-like 2 | -0.0371106 |
| CADM1 | cell adhesion molecule 1 | -0.0362176 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0344678 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0343241 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0336824 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0336567 |
| AUTS2 | autism susceptibility candidate 2 | -0.0335847 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0321527 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0313089 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0282137 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0281916 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0277207 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0276168 |
| FHIT | fragile histidine triad | -0.0267025 |
| CENPF | centromere protein F, 350/400kDa | -0.0266646 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0266031 |
| B2M | beta-2-microglobulin | -0.0264805 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0264664 |
| FOXP1 | forkhead box P1 | -0.0263303 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244295 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0244169 |
| FRMD4A | FERM domain containing 4A | -0.0242116 |
| SEPTIN9 | septin 9 | -0.0238661 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.02378 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0236888 |
| DIAPH2 | diaphanous-related formin 2 | -0.0235447 |
| ATXN1 | ataxin 1 | -0.0232446 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0230238 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0227504 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0226262 |
| INTS6 | integrator complex subunit 6 | -0.0223509 |
| FTL | ferritin, light polypeptide | -0.0219051 |
| RNF213 | ring finger protein 213 | -0.0218585 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0218316 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0218259 |
| ASPH | aspartate beta-hydroxylase | -0.0215859 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0213854 |
| CUX1 | cut-like homeobox 1 | -0.021046 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0202815 |
| ZNF638 | zinc finger protein 638 | -0.020263 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0201937 |
| STMN1 | stathmin 1 | -0.0199375 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0198203 |
| CNKSR3 | CNKSR family member 3 | -0.0193615 |
| RRBP1 | ribosome binding protein 1 | -0.0193054 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0192136 |
| ACTN4 | actinin, alpha 4 | -0.0191701 |
| SMYD3 | SET and MYND domain containing 3 | -0.0191359 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0190014 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.018922 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0187299 |
| BBX | bobby sox homolog (Drosophila) | -0.0186678 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.018581 |
| MYO10 | myosin X | -0.01858 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0185734 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0183627 |
| PHF21A | PHD finger protein 21A | -0.0183527 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0182751 |
| NRXN3 | neurexin 3 | -0.0182593 |
| SRPK2 | SRSF protein kinase 2 | -0.0182486 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0180347 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0180107 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0178441 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.0176385 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0176363 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0174402 |
| CDK13 | cyclin-dependent kinase 13 | -0.0173451 |
| ENTHD1 | ENTH domain containing 1 | -0.0173155 |
| PTMA | prothymosin, alpha | -0.0171013 |
| CABIN1 | calcineurin binding protein 1 | -0.0169233 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.016844 |
| CDH13 | cadherin 13 | -0.0166746 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0165202 |
| ARFGEF3 | ARFGEF family member 3 | -0.0163372 |
| EFNA5 | ephrin-A5 | -0.0162272 |
| EHBP1 | EH domain binding protein 1 | -0.0160874 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0160376 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0160084 |
| IFI44L | interferon-induced protein 44-like | -0.0159306 |
| HJURP | Holliday junction recognition protein | -0.0159199 |
| TPD52 | tumor protein D52 | -0.0158841 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0158811 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0158461 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0157013 |
| TNS1 | tensin 1 | -0.0155497 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0154793 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0153798 |
| PDE8A | phosphodiesterase 8A | -0.0153474 |
