| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.223167 |
| FN1 | fibronectin 1 | 0.214834 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.123446 |
| FKBP5 | FK506 binding protein 5 | 0.10809 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.102084 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0931942 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0908472 |
| LDHA | lactate dehydrogenase A | 0.0883953 |
| VEGFA | vascular endothelial growth factor A | 0.0833344 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0603112 |
| SDC4 | syndecan 4 | 0.0553126 |
| HMGA2 | high mobility group AT-hook 2 | 0.0546961 |
| FMNL2 | formin-like 2 | 0.054397 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0531918 |
| TOP1 | topoisomerase (DNA) I | 0.0519556 |
| PCBP3 | poly(rC) binding protein 3 | 0.0509658 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0504188 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0502359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0493776 |
| BICC1 | BicC family RNA binding protein 1 | 0.0477677 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0460306 |
| HOMER2 | homer scaffolding protein 2 | 0.0446494 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0444286 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0432361 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0430084 |
| FLNB | filamin B, beta | 0.0429361 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0425052 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.042267 |
| NDRG1 | N-myc downstream regulated 1 | 0.0413017 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0410792 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0400653 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0395721 |
| JAK1 | Janus kinase 1 | 0.0392324 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0391664 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0389874 |
| CD44 | CD44 molecule (Indian blood group) | 0.0383955 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0382243 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0377103 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0374585 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0369575 |
| MYO1B | myosin IB | 0.0368001 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0364281 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0359147 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0353264 |
| TNS3 | tensin 3 | 0.0347872 |
| UTRN | utrophin | 0.0347864 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0346396 |
| C3 | complement component 3 | 0.0344505 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0344347 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0343408 |
| HLA-A | major histocompatibility complex, class I, A | 0.0340592 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0335411 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0334169 |
| MSN | moesin | 0.0332027 |
| ERBIN | erbb2 interacting protein | 0.0331053 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0329432 |
| DIAPH2 | diaphanous-related formin 2 | 0.0327573 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0321955 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0320929 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0320282 |
| EGFR | epidermal growth factor receptor | 0.0318518 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0318483 |
| CD109 | CD109 molecule | 0.0306551 |
| CLMP | CXADR-like membrane protein | 0.0305904 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0303899 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0302875 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0302813 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0302439 |
| VMP1 | vacuole membrane protein 1 | 0.0301247 |
| FOXO3 | forkhead box O3 | 0.0301194 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0294495 |
| MT1X | metallothionein 1X | 0.0292158 |
| LOX | lysyl oxidase | 0.0291521 |
| STC2 | stanniocalcin 2 | 0.0287846 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0283403 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0282269 |
| MED13L | mediator complex subunit 13-like | 0.0281943 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0279639 |
| PLIN2 | perilipin 2 | 0.027946 |
| PTK2 | protein tyrosine kinase 2 | 0.0278326 |
| EZR | ezrin | 0.027819 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.027471 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.027377 |
| HDAC9 | histone deacetylase 9 | 0.0271923 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0271738 |
| PCBP2 | poly(rC) binding protein 2 | 0.0269613 |
| POTEF | POTE ankyrin domain family, member F | 0.0268692 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0268257 |
| INTS6 | integrator complex subunit 6 | 0.0262025 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0257428 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0257035 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0256249 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0254871 |
| IL6ST | interleukin 6 signal transducer | 0.0254825 |
| ADM | adrenomedullin | 0.0254399 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0252903 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.024878 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0248069 |
| KLF9 | Kruppel-like factor 9 | 0.0243484 |
| CALR | calreticulin | 0.0243228 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IER3 | immediate early response 3 | -0.0928802 |
| FTL | ferritin, light polypeptide | -0.0816986 |
| PGK1 | phosphoglycerate kinase 1 | -0.0816951 |
| VIM | vimentin | -0.072753 |
| TMSB10 | thymosin beta 10 | -0.0727419 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0704716 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0703022 |
| CADM1 | cell adhesion molecule 1 | -0.0648349 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0645259 |
| MKI67 | marker of proliferation Ki-67 | -0.0588717 |
| RPL12 | ribosomal protein L12 | -0.0556511 |
| PTMA | prothymosin, alpha | -0.0499216 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0472133 |
| TMSB4X | thymosin beta 4, X-linked | -0.0445577 |
| MT2A | metallothionein 2A | -0.0411565 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0406557 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392714 |
| RPL32 | ribosomal protein L32 | -0.0384262 |
| RPS24 | ribosomal protein S24 | -0.0382998 |
| RPLP0 | ribosomal protein, large, P0 | -0.0372987 |
| ENO1 | enolase 1, (alpha) | -0.0364534 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0361214 |
| EGR1 | early growth response 1 | -0.0357199 |
| GNAS | GNAS complex locus | -0.0356586 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0355398 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0350416 |
| FRMD4A | FERM domain containing 4A | -0.0348209 |
| B2M | beta-2-microglobulin | -0.034352 |
| CENPF | centromere protein F, 350/400kDa | -0.0330043 |
| ANLN | anillin, actin binding protein | -0.0329283 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0328622 |
| RPS8 | ribosomal protein S8 | -0.0319305 |
| KIF4A | kinesin family member 4A | -0.0313534 |
| KYNU | kynureninase | -0.0312912 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0312048 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0307901 |
| PLPP6 | phospholipid phosphatase 6 | -0.0306405 |
| RPL35 | ribosomal protein L35 | -0.0303514 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.030304 |
| RPL23 | ribosomal protein L23 | -0.0293688 |
| SYAP1 | synapse associated protein 1 | -0.028226 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0281856 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0281765 |
| FAM162A | family with sequence similarity 162, member A | -0.0270475 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0268918 |
| RPL19 | ribosomal protein L19 | -0.0264773 |
| RPS3 | ribosomal protein S3 | -0.0264695 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0256591 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253398 |
| FRMD5 | FERM domain containing 5 | -0.0252486 |
| ZNF292 | zinc finger protein 292 | -0.024958 |
| RPL14 | ribosomal protein L14 | -0.0248779 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0247588 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0247486 |
| RAI1 | retinoic acid induced 1 | -0.0246421 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0244605 |
| TUBB | tubulin, beta class I | -0.0241097 |
| RPS14 | ribosomal protein S14 | -0.0240386 |
| HMGB2 | high mobility group box 2 | -0.0236285 |
| ARRDC3 | arrestin domain containing 3 | -0.0233191 |
| RPL9 | ribosomal protein L9 | -0.0232831 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0232648 |
| RPS19 | ribosomal protein S19 | -0.0231423 |
| PRR11 | proline rich 11 | -0.0231416 |
| RPL37A | ribosomal protein L37a | -0.0228861 |
| RPS6 | ribosomal protein S6 | -0.0228446 |
| RPL26 | ribosomal protein L26 | -0.0227048 |
| TKT | transketolase | -0.0220255 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.021741 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0216153 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0212039 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0207651 |
| RACK1 | receptor for activated C kinase 1 | -0.0205876 |
| RPL36 | ribosomal protein L36 | -0.0205471 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0204981 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0203986 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0202449 |
| TMEM123 | transmembrane protein 123 | -0.0201666 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.020164 |
| CDCP1 | CUB domain containing protein 1 | -0.0200696 |
| SMAD3 | SMAD family member 3 | -0.0199489 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0198768 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0195647 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0195137 |
| LMNA | lamin A/C | -0.0193737 |
| RAD21 | RAD21 homolog (S. pombe) | -0.019346 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0193448 |
| JUN | jun proto-oncogene | -0.0191725 |
| NRN1 | neuritin 1 | -0.0190362 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0189893 |
| TUSC3 | tumor suppressor candidate 3 | -0.0186382 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0186087 |
| IER2 | immediate early response 2 | -0.0185175 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0184279 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0184269 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0184169 |
| RPS4X | ribosomal protein S4, X-linked | -0.0183125 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0181245 |
| RPL18 | ribosomal protein L18 | -0.0180931 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0180617 |
