| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Betamethasone dipropionate_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0926862 |
| FN1 | fibronectin 1 | 0.0733629 |
| MT2A | metallothionein 2A | 0.0662634 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0629789 |
| MT1X | metallothionein 1X | 0.0519463 |
| LAMB1 | laminin, beta 1 | 0.0411376 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0409294 |
| TOP1 | topoisomerase (DNA) I | 0.0375575 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0308186 |
| MT1E | metallothionein 1E | 0.0298031 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0296583 |
| HMGB2 | high mobility group box 2 | 0.0291049 |
| CDK6 | cyclin-dependent kinase 6 | 0.0271103 |
| HIP1 | huntingtin interacting protein 1 | 0.0268156 |
| IGF2 | insulin-like growth factor 2 | 0.0264232 |
| APP | amyloid beta (A4) precursor protein | 0.0263258 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0256712 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0254105 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.023997 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0237884 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0236748 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0228722 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0220753 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0218007 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0214727 |
| WWOX | WW domain containing oxidoreductase | 0.0213413 |
| MSN | moesin | 0.0206229 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0203049 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0202529 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0199554 |
| FKBP5 | FK506 binding protein 5 | 0.0198678 |
| CREBBP | CREB binding protein | 0.0198678 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0193998 |
| FAM168B | family with sequence similarity 168, member B | 0.0192154 |
| MRTFA | myocardin related transcription factor A | 0.0187621 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0184864 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0184154 |
| RPS3 | ribosomal protein S3 | 0.018285 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.017836 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | 0.0175762 |
| NEBL | nebulette | 0.0174208 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.017342 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0172849 |
| FOXO1 | forkhead box O1 | 0.0172832 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0171127 |
| NCKAP1 | NCK-associated protein 1 | 0.0171079 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0170391 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0169562 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0169236 |
| WDR43 | WD repeat domain 43 | 0.0167985 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0167316 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0165599 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0165382 |
| SVIL | supervillin | 0.0164898 |
| PTK2 | protein tyrosine kinase 2 | 0.0164172 |
| RPLP1 | ribosomal protein, large, P1 | 0.016415 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0164119 |
| GPATCH8 | G patch domain containing 8 | 0.0163869 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0163189 |
| ZNF148 | zinc finger protein 148 | 0.0163011 |
| PTMA | prothymosin, alpha | 0.0162951 |
| SRGN | serglycin | 0.0162654 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0162069 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0160457 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0159903 |
| MYO1E | myosin IE | 0.015788 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0156736 |
| MED13 | mediator complex subunit 13 | 0.0155777 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0155318 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0155006 |
| IRS2 | insulin receptor substrate 2 | 0.0152558 |
| JAK1 | Janus kinase 1 | 0.0151934 |
| CCN4 | cellular communication network factor 4 | 0.0151588 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0151474 |
| TJP1 | tight junction protein 1 | 0.0148813 |
| PKM | pyruvate kinase, muscle | 0.0148681 |
| EP300 | E1A binding protein p300 | 0.0147873 |
| RPS4X | ribosomal protein S4, X-linked | 0.0147857 |
| DNER | delta/notch-like EGF repeat containing | 0.014779 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0146687 |
| TRIM33 | tripartite motif containing 33 | 0.0146488 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0146224 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0145807 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0145675 |
| STAG2 | stromal antigen 2 | 0.0145656 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0145618 |
| POTEF | POTE ankyrin domain family, member F | 0.0144921 |
| EMC10 | ER membrane protein complex subunit 10 | 0.0144807 |
| PARD3 | par-3 family cell polarity regulator | 0.0143084 |
| TPM3 | tropomyosin 3 | 0.0142618 |
| DSTN | destrin (actin depolymerizing factor) | 0.0142265 |
| CEP95 | centrosomal protein 95kDa | 0.0142077 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0141786 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0141605 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0141409 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0140008 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0139219 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0138073 |
| KLF9 | Kruppel-like factor 9 | 0.0137816 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0136915 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132908 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122333 |
| COL6A3 | collagen, type VI, alpha 3 | -0.111733 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.105754 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0749648 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0720036 |
| CD44 | CD44 molecule (Indian blood group) | -0.0675093 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0647622 |
| ATP13A3 | ATPase type 13A3 | -0.0555391 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0521672 |
| NDRG1 | N-myc downstream regulated 1 | -0.0507602 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0477457 |
| NRXN3 | neurexin 3 | -0.0466359 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0446209 |
| CALD1 | caldesmon 1 | -0.0429147 |
| PRELID2 | PRELI domain containing 2 | -0.0417405 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0393856 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.038631 |
| COL1A2 | collagen, type I, alpha 2 | -0.0382214 |
| LOXL2 | lysyl oxidase-like 2 | -0.0379755 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0371986 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0370886 |
| STC1 | stanniocalcin 1 | -0.033985 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0339437 |
| CDH13 | cadherin 13 | -0.0338487 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0333518 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0317349 |
| VIM | vimentin | -0.0314564 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0309304 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0305588 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0300695 |
| CADM1 | cell adhesion molecule 1 | -0.0295773 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0294033 |
| VCL | vinculin | -0.0290812 |
| COL5A1 | collagen, type V, alpha 1 | -0.0288451 |
| ASPH | aspartate beta-hydroxylase | -0.0284926 |
| HLA-B | major histocompatibility complex, class I, B | -0.02843 |
| SDC4 | syndecan 4 | -0.028406 |
| CALU | calumenin | -0.028293 |
| GLIS3 | GLIS family zinc finger 3 | -0.027833 |
| LOX | lysyl oxidase | -0.0276441 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0276351 |
| CANX | calnexin | -0.0275642 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0269119 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0269023 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.02653 |
| EGFR | epidermal growth factor receptor | -0.0263051 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.026152 |
| SFXN1 | sideroflexin 1 | -0.0256549 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0255238 |
| IL6 | interleukin 6 | -0.0252645 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0243159 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0242396 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0240021 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0239846 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0238673 |
| CALR | calreticulin | -0.0237268 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0231802 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0231713 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0231446 |
| MAP4 | microtubule-associated protein 4 | -0.0231225 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0230483 |
| MYO10 | myosin X | -0.0229418 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0228924 |
| AHNAK | AHNAK nucleoprotein | -0.0228456 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0228436 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0226161 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0224362 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0223515 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0222617 |
| SMAD3 | SMAD family member 3 | -0.0218808 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0218796 |
| RUNX1 | runt-related transcription factor 1 | -0.0218493 |
| ZNF292 | zinc finger protein 292 | -0.0217532 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0216838 |
| HLA-C | major histocompatibility complex, class I, C | -0.0216717 |
| MEF2A | myocyte enhancer factor 2A | -0.0215479 |
| RNF216 | ring finger protein 216 | -0.0214221 |
| FNIP1 | folliculin interacting protein 1 | -0.0212776 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0211281 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0209912 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0209244 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0207568 |
| EXOC6B | exocyst complex component 6B | -0.020508 |
| UBC | ubiquitin C | -0.020482 |
| HDLBP | high density lipoprotein binding protein | -0.0204255 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0204166 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0203049 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0202329 |
| NF1 | neurofibromin 1 | -0.0202224 |
| SEC24D | SEC24 family member D | -0.0200201 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0199054 |
| MYO9B | myosin IXB | -0.0198263 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0197863 |
| SEPTIN2 | septin 2 | -0.019607 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0195163 |
| PRKCA | protein kinase C, alpha | -0.0193526 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0192862 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0192218 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.018915 |
