Betamethasone dipropionate_SW48 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Betamethasone dipropionate perturbation in SW48 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Betamethasone dipropionate_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.118185
CD36 CD36 molecule (thrombospondin receptor) 0.107257
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0916181
RPS3 ribosomal protein S3 0.074832
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0746186
PTMA prothymosin, alpha 0.0703808
EEF2 eukaryotic translation elongation factor 2 0.0690071
RPS4X ribosomal protein S4, X-linked 0.0624908
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0610055
RPS6 ribosomal protein S6 0.0608716
OXR1 oxidation resistance 1 0.0580561
RPL3 ribosomal protein L3 0.055222
TMSB10 thymosin beta 10 0.0473864
LOC112694756 uncharaterized LOC112694756 0.0463286
ENO1 enolase 1, (alpha) 0.0445489
SRRM2 serine/arginine repetitive matrix 2 0.0439449
LDHA lactate dehydrogenase A 0.043341
RNF43 ring finger protein 43 0.0429318
EREG epiregulin 0.0409181
RPL26 ribosomal protein L26 0.0408381
RPL11 ribosomal protein L11 0.0407217
PKM pyruvate kinase, muscle 0.0406041
FAT1 FAT atypical cadherin 1 0.0403589
AXIN2 axin 2 0.0384996
RPS12 ribosomal protein S12 0.0374852
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0369493
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0366052
ANXA1 annexin A1 0.0352469
RUNX2 runt-related transcription factor 2 0.034645
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0345222
PDE4B phosphodiesterase 4B, cAMP-specific 0.0337594
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.033757
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0330616
AREG amphiregulin 0.0326812
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0320487
GOLGA4 golgin A4 0.0318505
MKI67 marker of proliferation Ki-67 0.0312028
RPS2 ribosomal protein S2 0.0310592
RPL12 ribosomal protein L12 0.0296986
RPLP1 ribosomal protein, large, P1 0.0275153
RPL17-C18ORF32 RPL17-C18orf32 readthrough 0.0267834
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0261078
RPLP0 ribosomal protein, large, P0 0.0254468
USP3 ubiquitin specific peptidase 3 0.0254083
HMGB2 high mobility group box 2 0.0253624
RACK1 receptor for activated C kinase 1 0.0250351
RPL37A ribosomal protein L37a 0.024786
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0247287
SET SET nuclear proto-oncogene 0.0243003
RPL4 ribosomal protein L4 0.0242
DSPP dentin sialophosphoprotein 0.0241095
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0240829
MATR3 matrin 3 0.0238793
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0238407
KITLG KIT ligand 0.0234236
LMAN1 lectin, mannose-binding, 1 0.0233723
BIRC3 baculoviral IAP repeat containing 3 0.0225631
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0223679
RPS17 ribosomal protein S17 0.0221359
UBA6 ubiquitin-like modifier activating enzyme 6 0.022094
CSDE1 cold shock domain containing E1, RNA-binding 0.0218128
TXNRD1 thioredoxin reductase 1 0.021786
HSPA8 heat shock 70kDa protein 8 0.0217041
PKP4 plakophilin 4 0.0216944
RPL35A ribosomal protein L35a 0.0216482
RPL36 ribosomal protein L36 0.0214437
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0212802
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.0211699
CENPF centromere protein F, 350/400kDa 0.0208517
RSL1D1 ribosomal L1 domain containing 1 0.019921
GPR15 G protein-coupled receptor 15 0.0199192
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.0196063
SSR1 signal sequence receptor, alpha 0.0195837
NAP1L1 nucleosome assembly protein 1-like 1 0.0194567
BTN3A3 butyrophilin, subfamily 3, member A3 0.0194199
TOP1 topoisomerase (DNA) I 0.0193471
RPS8 ribosomal protein S8 0.0191252
CKAP5 cytoskeleton associated protein 5 0.0188349
RPL29 ribosomal protein L29 0.0187992
RPL23 ribosomal protein L23 0.0186635
EVA1C eva-1 homolog C (C. elegans) 0.0184432
SCFD1 sec1 family domain containing 1 0.0182563
XPC xeroderma pigmentosum, complementation group C 0.0177463
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0176443
PTEN phosphatase and tensin homolog 0.0176356
NFXL1 nuclear transcription factor, X-box binding-like 1 0.0176302
ARID5B AT rich interactive domain 5B (MRF1-like) 0.0174569
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0170511
ESRP1 epithelial splicing regulatory protein 1 0.0170249
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.0168852
IGFBP3 insulin-like growth factor binding protein 3 0.0168776
ZMYM2 zinc finger, MYM-type 2 0.0168425
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0167932
PCM1 pericentriolar material 1 0.0166483
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0163313
TGFB2 transforming growth factor, beta 2 0.016018
ARHGAP42 Rho GTPase activating protein 42 0.0159197
CBX3 chromobox homolog 3 0.0158803
GOLGA2 golgin A2 0.0156398
OAZ1 ornithine decarboxylase antizyme 1 0.0154142

decreased expression

Symbol Name Standardized Value
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.136999
HMGA2 high mobility group AT-hook 2 -0.0735008
ACTG1 actin gamma 1 -0.0581981
VCL vinculin -0.0567822
RCOR1 REST corepressor 1 -0.0552751
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0549568
LAMA4 laminin, alpha 4 -0.0469149
IER3 immediate early response 3 -0.0467712
EMP1 epithelial membrane protein 1 -0.0460625
SNX9 sorting nexin 9 -0.0423728
LMO7 LIM domain 7 -0.039487
AKAP13 A kinase (PRKA) anchor protein 13 -0.0393709
FHIT fragile histidine triad -0.0393585
ANXA2 annexin A2 -0.0365551
LAMB3 laminin, beta 3 -0.0361246
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0350575
AK1 adenylate kinase 1 -0.0350218
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0344632
FHL2 four and a half LIM domains 2 -0.0313191
CUX1 cut-like homeobox 1 -0.0297029
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0285417
NUP50 nucleoporin 50kDa -0.0282739
TPT1 tumor protein, translationally-controlled 1 -0.0277419
FERMT1 fermitin family member 1 -0.02634
ANKRD17 ankyrin repeat domain 17 -0.0262191
SEPTIN9 septin 9 -0.0261328
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0260207
VMP1 vacuole membrane protein 1 -0.0255706
EGR1 early growth response 1 -0.0250724
RASAL2 RAS protein activator like 2 -0.0247545
JARID2 jumonji, AT rich interactive domain 2 -0.0247469
TRAF3 TNF receptor-associated factor 3 -0.0246617
ATXN1 ataxin 1 -0.024548
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0242501
CCSER1 coiled-coil serine-rich protein 1 -0.0236823
SH3RF2 SH3 domain containing ring finger 2 -0.02303
CMIP c-Maf inducing protein -0.0229516
EHBP1 EH domain binding protein 1 -0.0223526
DIAPH3 diaphanous-related formin 3 -0.0223093
UBC ubiquitin C -0.021352
SERINC5 serine incorporator 5 -0.0207947
GPC5 glypican 5 -0.0206422
FLOT1 flotillin 1 -0.0202468
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough -0.0201818
FMNL2 formin-like 2 -0.0199076
MACF1 microtubule-actin crosslinking factor 1 -0.0197015
EXT1 exostosin glycosyltransferase 1 -0.019596
RTN3 reticulon 3 -0.0195711
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0193184
CALU calumenin -0.0187958
OXSR1 oxidative stress responsive 1 -0.0187168
SMAD3 SMAD family member 3 -0.01843
MYO1E myosin IE -0.0183641
EXOC4 exocyst complex component 4 -0.0183287
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0182942
ANKRD10 ankyrin repeat domain 10 -0.0179151
SDC4 syndecan 4 -0.0177068
EFNB2 ephrin-B2 -0.0176557
MPRIP myosin phosphatase Rho interacting protein -0.0175293
RPS15 ribosomal protein S15 -0.0174787
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -0.0170204
ATP5F1B ATP synthase F1 subunit beta -0.0170013
FUS FUS RNA binding protein -0.0168961
RRM2 ribonucleotide reductase M2 -0.0168791
SERTAD2 SERTA domain containing 2 -0.0168232
KLF5 Kruppel-like factor 5 (intestinal) -0.0167761
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0164379
ZFAND3 zinc finger, AN1-type domain 3 -0.0164043
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0162278
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0162277
RPS23 ribosomal protein S23 -0.0161044
NF1 neurofibromin 1 -0.0160107
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0159265
GPHN gephyrin -0.015922
USP34 ubiquitin specific peptidase 34 -0.0158209
PDE10A phosphodiesterase 10A -0.0157223
USP9X ubiquitin specific peptidase 9, X-linked -0.0156138
RSU1 Ras suppressor protein 1 -0.0155991
RREB1 ras responsive element binding protein 1 -0.0155952
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0155194
TPM4 tropomyosin 4 -0.0155175
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0154242
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0153753
RPLP2 ribosomal protein, large, P2 -0.0153319
CLIC4 chloride intracellular channel 4 -0.0152103
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0151606
FBXO11 F-box protein 11 -0.0151087
PLAUR plasminogen activator, urokinase receptor -0.0150008
PARD6B par-6 family cell polarity regulator beta -0.014914
SLC38A2 solute carrier family 38, member 2 -0.0145973
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0145895
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0144679
MCU mitochondrial calcium uniporter -0.0144665
SGMS2 sphingomyelin synthase 2 -0.0144318
NFE2L2 nuclear factor, erythroid 2-like 2 -0.01435
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0142508
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0142342
KLF6 Kruppel-like factor 6 -0.0142113
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0141759
ABR active BCR-related -0.0141022