| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Betamethasone dipropionate perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Betamethasone dipropionate_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.247413 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.204981 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0872525 |
| COL1A1 | collagen, type I, alpha 1 | 0.0753324 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0729708 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0585713 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0493399 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0452378 |
| HLA-B | major histocompatibility complex, class I, B | 0.0399864 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0398697 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0389783 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0384159 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0379367 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0341507 |
| DNER | delta/notch-like EGF repeat containing | 0.032251 |
| VCL | vinculin | 0.0322303 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0311228 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0297948 |
| CAVIN1 | caveolae associated protein 1 | 0.0294824 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0282707 |
| HMGA2 | high mobility group AT-hook 2 | 0.0280288 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0278474 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0265157 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0262873 |
| LDHA | lactate dehydrogenase A | 0.0259469 |
| POTEF | POTE ankyrin domain family, member F | 0.0255268 |
| MED13L | mediator complex subunit 13-like | 0.024449 |
| AHNAK | AHNAK nucleoprotein | 0.0243986 |
| COL3A1 | collagen, type III, alpha 1 | 0.0241193 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.024093 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.023543 |
| LOX | lysyl oxidase | 0.0233934 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0231357 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0231144 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0230816 |
| ASPH | aspartate beta-hydroxylase | 0.0229817 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0222364 |
| PTX3 | pentraxin 3, long | 0.0222303 |
| FKBP5 | FK506 binding protein 5 | 0.0215992 |
| PTMA | prothymosin, alpha | 0.0212703 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0210535 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0207123 |
| ANXA2 | annexin A2 | 0.0205595 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0204441 |
| APP | amyloid beta (A4) precursor protein | 0.0201147 |
| VGLL3 | vestigial-like family member 3 | 0.0198222 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.01962 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0191297 |
| SRGN | serglycin | 0.0190664 |
| CDH13 | cadherin 13 | 0.0190524 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0187928 |
| PRELID2 | PRELI domain containing 2 | 0.0185529 |
| MT2A | metallothionein 2A | 0.0180273 |
| JAK1 | Janus kinase 1 | 0.0177416 |
| IGF2 | insulin-like growth factor 2 | 0.0175615 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0175456 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.017311 |
| IRS2 | insulin receptor substrate 2 | 0.0171683 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0171418 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0170884 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0170679 |
| ACTG1 | actin gamma 1 | 0.0167815 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0166908 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0166564 |
| TMEM87A | transmembrane protein 87A | 0.0164986 |
| TPM4 | tropomyosin 4 | 0.0163916 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0163526 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0163441 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0163032 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0160853 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0157765 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0157003 |
| ZFHX3 | zinc finger homeobox 3 | 0.0155775 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0155675 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0153078 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0151862 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0149442 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0148967 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0147274 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0146644 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0146272 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0145224 |
| RPL26 | ribosomal protein L26 | 0.014462 |
| INTS6 | integrator complex subunit 6 | 0.0144271 |
| AEBP2 | AE binding protein 2 | 0.0143985 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0143191 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0140896 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0140869 |
| SFTPA2 | surfactant protein A2 | 0.0137692 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0137374 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0137047 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0135654 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0133787 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0133683 |
| RPS8 | ribosomal protein S8 | 0.0133376 |
| FUS | FUS RNA binding protein | 0.0133056 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0131734 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0131068 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0130357 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0129071 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.176723 |
| VIM | vimentin | -0.119764 |
| INHBA | inhibin, beta A | -0.113475 |
| NDRG1 | N-myc downstream regulated 1 | -0.102682 |
| STC1 | stanniocalcin 1 | -0.0806205 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0791975 |
| CD44 | CD44 molecule (Indian blood group) | -0.0620518 |
| ATP13A3 | ATPase type 13A3 | -0.056869 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0461109 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0410258 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0401708 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0373976 |
| FTL | ferritin, light polypeptide | -0.036067 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0354613 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0345905 |
| RUNX1 | runt-related transcription factor 1 | -0.0338278 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0313596 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0309941 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0307715 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0297716 |
| PDE8A | phosphodiesterase 8A | -0.0285778 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0280487 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0276998 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0262421 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0252383 |
| MYO10 | myosin X | -0.0248691 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0247389 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.024434 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0231066 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0230929 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0230008 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0227546 |
| RNF145 | ring finger protein 145 | -0.0225107 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0224945 |
| SMAD3 | SMAD family member 3 | -0.0222068 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0221541 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0221182 |
| PLPP3 | phospholipid phosphatase 3 | -0.0203841 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.019899 |
| MAP1B | microtubule-associated protein 1B | -0.0196565 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0194083 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0194057 |
| FRMD6 | FERM domain containing 6 | -0.0186058 |
| EMP1 | epithelial membrane protein 1 | -0.0185303 |
| PFN1 | profilin 1 | -0.0185046 |
| IER3 | immediate early response 3 | -0.018304 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0182472 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0181854 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0176503 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.017318 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0173089 |
| COL6A3 | collagen, type VI, alpha 3 | -0.017289 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0171247 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0166625 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0164894 |
| ARRDC3 | arrestin domain containing 3 | -0.0164601 |
| ADM | adrenomedullin | -0.0164025 |
| COL1A2 | collagen, type I, alpha 2 | -0.0163239 |
| TPI1 | triosephosphate isomerase 1 | -0.0154862 |
| ANO6 | anoctamin 6 | -0.0153554 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.015245 |
| FOSL1 | FOS-like antigen 1 | -0.0151181 |
| NGLY1 | N-glycanase 1 | -0.0150554 |
| GPHN | gephyrin | -0.0149257 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0148939 |
| INSIG1 | insulin induced gene 1 | -0.0144703 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0144644 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0142516 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0141751 |
| RAI14 | retinoic acid induced 14 | -0.0141397 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0140414 |
| B2M | beta-2-microglobulin | -0.0139759 |
| APAF1 | apoptotic peptidase activating factor 1 | -0.0139302 |
| USP3 | ubiquitin specific peptidase 3 | -0.0137838 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0137662 |
| IL6 | interleukin 6 | -0.0135748 |
| IKBIP | IKBKB interacting protein | -0.0133657 |
| DUSP10 | dual specificity phosphatase 10 | -0.013212 |
| ZNF292 | zinc finger protein 292 | -0.0129964 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0128405 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0127792 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0127548 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0124354 |
| AXL | AXL receptor tyrosine kinase | -0.012432 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0121649 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0120518 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0120352 |
| CALU | calumenin | -0.0119532 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0118392 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0117912 |
| VEGFC | vascular endothelial growth factor C | -0.0117901 |
| RAI1 | retinoic acid induced 1 | -0.0117593 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0117209 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0116761 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.0116565 |
| SNX9 | sorting nexin 9 | -0.0116522 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0116337 |
| TAPBP | TAP binding protein (tapasin) | -0.0115053 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0114952 |
| GOLGA4 | golgin A4 | -0.0114396 |
