| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bexarotene_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.241996 |
| HMGA2 | high mobility group AT-hook 2 | 0.111758 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0666546 |
| INTS6 | integrator complex subunit 6 | 0.0633409 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0593538 |
| ASPH | aspartate beta-hydroxylase | 0.055789 |
| NLGN1 | neuroligin 1 | 0.0508707 |
| YAP1 | Yes-associated protein 1 | 0.0494318 |
| RRM2 | ribonucleotide reductase M2 | 0.0445575 |
| EHBP1 | EH domain binding protein 1 | 0.0438648 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0438372 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0404272 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0388151 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0369562 |
| MTAP | methylthioadenosine phosphorylase | 0.0366851 |
| ADIPOR2 | adiponectin receptor 2 | 0.0364307 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0362484 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0356718 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0344077 |
| HSPA8 | heat shock 70kDa protein 8 | 0.032633 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0322148 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0300345 |
| GOLGB1 | golgin B1 | 0.0298505 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0289728 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0281222 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | 0.0275567 |
| PRELID2 | PRELI domain containing 2 | 0.0271869 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0261298 |
| PCDH7 | protocadherin 7 | 0.0260879 |
| VMP1 | vacuole membrane protein 1 | 0.025717 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0255466 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0252455 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0251431 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.024727 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0246417 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0241626 |
| JMJD1C | jumonji domain containing 1C | 0.0238873 |
| PCDH9 | protocadherin 9 | 0.0237401 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0229212 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0228066 |
| RCOR1 | REST corepressor 1 | 0.0225815 |
| EXOC4 | exocyst complex component 4 | 0.0224887 |
| PRKCE | protein kinase C, epsilon | 0.0221501 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0219971 |
| PCNX4 | pecanex 4 | 0.0218712 |
| EPHA6 | EPH receptor A6 | 0.0213856 |
| ZNF638 | zinc finger protein 638 | 0.0208149 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0207535 |
| LRRC23 | leucine rich repeat containing 23 | 0.0202482 |
| CUX1 | cut-like homeobox 1 | 0.0201971 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0196818 |
| RAB10 | RAB10, member RAS oncogene family | 0.0194905 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0192841 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.018693 |
| BCHE | butyrylcholinesterase | 0.0186154 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0185157 |
| PTK2 | protein tyrosine kinase 2 | 0.0184441 |
| YBX3 | Y box binding protein 3 | 0.0182629 |
| GCG | glucagon | 0.0180939 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0180466 |
| AEBP2 | AE binding protein 2 | 0.0178735 |
| NEBL | nebulette | 0.0176307 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0174803 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0174553 |
| SERTAD2 | SERTA domain containing 2 | 0.0173623 |
| ABI2 | abl-interactor 2 | 0.0173311 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0172159 |
| CANX | calnexin | 0.0171798 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0171017 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0166818 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0165672 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0164728 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0164446 |
| ZNF644 | zinc finger protein 644 | 0.0162449 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0162178 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0162114 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.016139 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0160733 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0157314 |
| DIAPH3 | diaphanous-related formin 3 | 0.015711 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0155955 |
| DTNB | dystrobrevin, beta | 0.0154482 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0151041 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0149337 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0148477 |
| NUP98 | nucleoporin 98kDa | 0.0146807 |
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.0145763 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0145286 |
| GPATCH2L | G patch domain containing 2-like | 0.0144987 |
| FADS2 | fatty acid desaturase 2 | 0.0144141 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0142993 |
| EGR1 | early growth response 1 | 0.0142686 |
| WASF1 | WAS protein family, member 1 | 0.0141316 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0141069 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0140964 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0140778 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0139489 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0138886 |
| RUNX1 | runt-related transcription factor 1 | 0.0137762 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0137555 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.199254 |
| AREG | amphiregulin | -0.12126 |
| TMSB10 | thymosin beta 10 | -0.10359 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0830134 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.08 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0751558 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0709108 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0700475 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0611541 |
| PTMA | prothymosin, alpha | -0.0593942 |
| PCBP2 | poly(rC) binding protein 2 | -0.0542195 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0492574 |
| UBC | ubiquitin C | -0.0440664 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0426868 |
| CCNL1 | cyclin L1 | -0.0415822 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0401417 |
| RPL23 | ribosomal protein L23 | -0.0397886 |
| EDN1 | endothelin 1 | -0.0396125 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0395016 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0377068 |
| RBM39 | RNA binding motif protein 39 | -0.0369467 |
| XPO1 | exportin 1 | -0.0367898 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0354206 |
| DST | dystonin | -0.0342064 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0325476 |
| RPS27A | ribosomal protein S27a | -0.032412 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0323442 |
| CCN2 | cellular communication network factor 2 | -0.0321269 |
| TXNRD1 | thioredoxin reductase 1 | -0.0318063 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0317462 |
| NF1 | neurofibromin 1 | -0.0314689 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0309558 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0308794 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0307773 |
| PFN1 | profilin 1 | -0.030432 |
| ECT2 | epithelial cell transforming 2 | -0.0303094 |
| LDHB | lactate dehydrogenase B | -0.0302038 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0299546 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0298826 |
| RASAL2 | RAS protein activator like 2 | -0.0296486 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0293789 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0291851 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0290639 |
| HMGA1 | high mobility group AT-hook 1 | -0.0290128 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0283427 |
| ZNF292 | zinc finger protein 292 | -0.0282042 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0281395 |
| SYT1 | synaptotagmin I | -0.0280186 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0273736 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0272758 |
| CLDN1 | claudin 1 | -0.027128 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.026886 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0267111 |
| MGAT4C | MGAT4 family, member C | -0.0266365 |
| WDR43 | WD repeat domain 43 | -0.0266082 |
| RBM25 | RNA binding motif protein 25 | -0.0264712 |
| KIF5B | kinesin family member 5B | -0.0264127 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0263628 |
| MED13L | mediator complex subunit 13-like | -0.0262612 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0256302 |
| TMEM123 | transmembrane protein 123 | -0.025542 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0252602 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0247616 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.024746 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0245576 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0243849 |
| POTEF | POTE ankyrin domain family, member F | -0.0242832 |
| RPS24 | ribosomal protein S24 | -0.0242341 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0240499 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0240076 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0237969 |
| RPL34 | ribosomal protein L34 | -0.0231974 |
| RPL35A | ribosomal protein L35a | -0.0231225 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0230853 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0229446 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0228619 |
| MYL12B | myosin, light chain 12B, regulatory | -0.022828 |
| RPS16 | ribosomal protein S16 | -0.022704 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0227008 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.022681 |
| RPS3 | ribosomal protein S3 | -0.0226408 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0225824 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0225233 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.022427 |
| SEPTIN7 | septin 7 | -0.0221886 |
| LMO7 | LIM domain 7 | -0.0219805 |
| TFG | TRK-fused gene | -0.0219499 |
| CCNI | cyclin I | -0.0217649 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0217492 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0217075 |
| MMP12 | matrix metallopeptidase 12 | -0.021674 |
| WDR45B | WD repeat domain 45B | -0.0216262 |
| CPOX | coproporphyrinogen oxidase | -0.0215357 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0214883 |
| PLK2 | polo-like kinase 2 | -0.0214785 |
| RPL5 | ribosomal protein L5 | -0.0214383 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0213793 |
| RPLP2 | ribosomal protein, large, P2 | -0.0213577 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0213282 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0213026 |
