| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bexarotene_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.24955 |
| STC1 | stanniocalcin 1 | 0.217329 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.14481 |
| VEGFA | vascular endothelial growth factor A | 0.127446 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.122115 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0991465 |
| CALR | calreticulin | 0.0904902 |
| GOLGA4 | golgin A4 | 0.0866786 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0865783 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0726627 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.069939 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.069683 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0680092 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0631267 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0628093 |
| COL1A2 | collagen, type I, alpha 2 | 0.053201 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0485713 |
| CANX | calnexin | 0.0459576 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0435701 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0430432 |
| LOXL2 | lysyl oxidase-like 2 | 0.042381 |
| FBN1 | fibrillin 1 | 0.0421949 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0419175 |
| MLF1 | myeloid leukemia factor 1 | 0.0416458 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0413741 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0413525 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0407385 |
| COG5 | component of oligomeric golgi complex 5 | 0.0402597 |
| TMF1 | TATA element modulatory factor 1 | 0.0394431 |
| GOLGB1 | golgin B1 | 0.0392083 |
| COL5A1 | collagen, type V, alpha 1 | 0.0378957 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0367304 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0362951 |
| LOX | lysyl oxidase | 0.03579 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0346439 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0335552 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0334204 |
| SQLE | squalene epoxidase | 0.0313749 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0312634 |
| LDHA | lactate dehydrogenase A | 0.0312201 |
| RAB6A | RAB6A, member RAS oncogene family | 0.031058 |
| AHI1 | Abelson helper integration site 1 | 0.0303988 |
| HYOU1 | hypoxia up-regulated 1 | 0.0302732 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0297856 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0295623 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0294769 |
| COG6 | component of oligomeric golgi complex 6 | 0.0294747 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0291108 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0283311 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0280206 |
| SRP54 | signal recognition particle 54kDa | 0.0279822 |
| TPM3 | tropomyosin 3 | 0.0278305 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0277123 |
| TMEM41B | transmembrane protein 41B | 0.0273525 |
| RPL3 | ribosomal protein L3 | 0.0273245 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0269162 |
| POSTN | periostin, osteoblast specific factor | 0.0268418 |
| COL3A1 | collagen, type III, alpha 1 | 0.026326 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0262558 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0262113 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.026191 |
| PGM3 | phosphoglucomutase 3 | 0.0260699 |
| B2M | beta-2-microglobulin | 0.0259523 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0255917 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0255184 |
| ASPH | aspartate beta-hydroxylase | 0.0251674 |
| PTK2 | protein tyrosine kinase 2 | 0.0250868 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.025055 |
| ARF4 | ADP-ribosylation factor 4 | 0.0249263 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0247829 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0243917 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.024372 |
| TBC1D23 | TBC1 domain family, member 23 | 0.024288 |
| EVI5 | ecotropic viral integration site 5 | 0.0239011 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0234924 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0234891 |
| VIRMA | vir like m6A methyltransferase associated | 0.0231621 |
| CDK13 | cyclin-dependent kinase 13 | 0.0230933 |
| NBEAL1 | neurobeachin-like 1 | 0.02304 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0230009 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0228019 |
| MSN | moesin | 0.0227435 |
| AAK1 | AP2 associated kinase 1 | 0.0226663 |
| SMYD3 | SET and MYND domain containing 3 | 0.0221221 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0221062 |
| FAM20C | family with sequence similarity 20, member C | 0.0220931 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0220409 |
| HM13 | histocompatibility (minor) 13 | 0.0216889 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0215665 |
| GOLM2 | golgi membrane protein 2 | 0.0214806 |
| SUCO | SUN domain containing ossification factor | 0.0211954 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0211866 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0210377 |
| SNX3 | sorting nexin 3 | 0.020826 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0207376 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0205983 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0204177 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0202912 |
| ADM | adrenomedullin | 0.0202643 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0202583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.138181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12741 |
| IER3 | immediate early response 3 | -0.123131 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.115729 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0923839 |
| COL1A1 | collagen, type I, alpha 1 | -0.0891312 |
| CADM1 | cell adhesion molecule 1 | -0.0801354 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0782698 |
| PTMA | prothymosin, alpha | -0.0731718 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0729014 |
| TMSB10 | thymosin beta 10 | -0.072482 |
| CDH13 | cadherin 13 | -0.0683313 |
| FN1 | fibronectin 1 | -0.0681448 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0679116 |
| RPL35A | ribosomal protein L35a | -0.0657528 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0653104 |
| RPS6 | ribosomal protein S6 | -0.0643156 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0639699 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0588944 |
| AHNAK | AHNAK nucleoprotein | -0.0551796 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0506889 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0483786 |
| ACTG1 | actin gamma 1 | -0.0472966 |
| KLF6 | Kruppel-like factor 6 | -0.0468559 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0456069 |
| MT2A | metallothionein 2A | -0.0450911 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0450369 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0444291 |
| NAV2 | neuron navigator 2 | -0.0430417 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0417887 |
| RPS8 | ribosomal protein S8 | -0.0413098 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0411838 |
| INHBA | inhibin, beta A | -0.0405616 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.040256 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0401276 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.037745 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0373422 |
| RPL12 | ribosomal protein L12 | -0.0365661 |
| IL6ST | interleukin 6 signal transducer | -0.0364544 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0360067 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.035168 |
| CALD1 | caldesmon 1 | -0.0349805 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0347998 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0334814 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0331085 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0327262 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0325077 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0324979 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0321122 |
| RPL26 | ribosomal protein L26 | -0.0318305 |
| ATP13A3 | ATPase type 13A3 | -0.0312756 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0311082 |
| RHEB | Ras homolog enriched in brain | -0.0309045 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0306881 |
| EGFR | epidermal growth factor receptor | -0.0306813 |
| RPL23 | ribosomal protein L23 | -0.0305612 |
| RPS20 | ribosomal protein S20 | -0.0303067 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0301577 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.030079 |
| JAK1 | Janus kinase 1 | -0.0300781 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0297276 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0295607 |
| RPS24 | ribosomal protein S24 | -0.0295415 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0294393 |
| RPL19 | ribosomal protein L19 | -0.0289196 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0288031 |
| CNTN5 | contactin 5 | -0.0286298 |
| FTL | ferritin, light polypeptide | -0.028593 |
| S100A10 | S100 calcium binding protein A10 | -0.028574 |
| WTAP | Wilms tumor 1 associated protein | -0.0285506 |
| HMGB1 | high mobility group box 1 | -0.0284912 |
| CD44 | CD44 molecule (Indian blood group) | -0.0284514 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.028376 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0277794 |
| RPLP1 | ribosomal protein, large, P1 | -0.0276888 |
| SMAD3 | SMAD family member 3 | -0.0275068 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0273977 |
| BBX | bobby sox homolog (Drosophila) | -0.0270687 |
| RPL30 | ribosomal protein L30 | -0.0270386 |
| RPL37A | ribosomal protein L37a | -0.0268555 |
| SQSTM1 | sequestosome 1 | -0.0267255 |
| VCAN | versican | -0.0266202 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0261866 |
| SEPTIN7 | septin 7 | -0.0257647 |
| HAS2 | hyaluronan synthase 2 | -0.0256835 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0253776 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0252828 |
| IRF1 | interferon regulatory factor 1 | -0.0252787 |
| TMSB4X | thymosin beta 4, X-linked | -0.0251963 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0250426 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0249605 |
| POTEF | POTE ankyrin domain family, member F | -0.0248284 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0243455 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0243425 |
| RYBP | RING1 and YY1 binding protein | -0.0241865 |
| QKI | QKI, KH domain containing, RNA binding | -0.024116 |
| KLF10 | Kruppel-like factor 10 | -0.0231349 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0230534 |
| OGA | O-GlcNAcase | -0.0230216 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0229292 |
