| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bexarotene_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.190741 |
| LMO7 | LIM domain 7 | 0.0853288 |
| GDF15 | growth differentiation factor 15 | 0.0746363 |
| PTMA | prothymosin, alpha | 0.0709684 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.060874 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0602319 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.057731 |
| EPCAM | epithelial cell adhesion molecule | 0.0547373 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0543235 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0537451 |
| PGK1 | phosphoglycerate kinase 1 | 0.0521409 |
| AREG | amphiregulin | 0.0507529 |
| EREG | epiregulin | 0.0496847 |
| SHROOM3 | shroom family member 3 | 0.0472115 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0456571 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0452041 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0447283 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0411656 |
| CAB39 | calcium binding protein 39 | 0.0406592 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0403926 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.0402233 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0401963 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0386604 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0380368 |
| GOLGA4 | golgin A4 | 0.0377479 |
| DSPP | dentin sialophosphoprotein | 0.0371616 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0366704 |
| DSCAM | Down syndrome cell adhesion molecule | 0.036275 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.036271 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0361904 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0361416 |
| PIGR | polymeric immunoglobulin receptor | 0.0361046 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0359606 |
| RNF145 | ring finger protein 145 | 0.0359376 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0359153 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0347087 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0332226 |
| USP6NL | USP6 N-terminal like | 0.0332197 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0324468 |
| KIF5B | kinesin family member 5B | 0.0322811 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0318712 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0317847 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0315925 |
| OGA | O-GlcNAcase | 0.0310857 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0308548 |
| CD164 | CD164 molecule, sialomucin | 0.0308492 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0304225 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0304041 |
| EMP1 | epithelial membrane protein 1 | 0.0303985 |
| ZNF654 | zinc finger protein 654 | 0.0301811 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0301735 |
| MED13L | mediator complex subunit 13-like | 0.0297039 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0292284 |
| CD2AP | CD2-associated protein | 0.0288845 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.028795 |
| MED13 | mediator complex subunit 13 | 0.028684 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0285999 |
| HDLBP | high density lipoprotein binding protein | 0.0284282 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0278375 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0278119 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0276042 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0273496 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.027301 |
| EFNB2 | ephrin-B2 | 0.0271252 |
| TMSB4X | thymosin beta 4, X-linked | 0.0271106 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0270787 |
| LRRC1 | leucine rich repeat containing 1 | 0.0270558 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0269962 |
| PTK2 | protein tyrosine kinase 2 | 0.0269865 |
| ETNK1 | ethanolamine kinase 1 | 0.0268868 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.0267282 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0264573 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0264555 |
| H1-0 | H1.0 linker histone | 0.0264014 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0259766 |
| THOC2 | THO complex 2 | 0.0258518 |
| RRBP1 | ribosome binding protein 1 | 0.0258498 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0258416 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0257666 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0257452 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0255726 |
| CEP350 | centrosomal protein 350kDa | 0.0254811 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0252116 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0251815 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.025092 |
| TMEM135 | transmembrane protein 135 | 0.0250379 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.024902 |
| GDA | guanine deaminase | 0.0244595 |
| TC2N | tandem C2 domains, nuclear | 0.0244306 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0241957 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0241558 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.0241235 |
| DSG2 | desmoglein 2 | 0.0239654 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0239077 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0238141 |
| RPS23 | ribosomal protein S23 | 0.0237233 |
| CDK19 | cyclin-dependent kinase 19 | 0.0235685 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0235101 |
| TRIM24 | tripartite motif containing 24 | 0.0235022 |
| ERBIN | erbb2 interacting protein | 0.0234478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.192523 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.180776 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.149093 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.13257 |
| NDRG1 | N-myc downstream regulated 1 | -0.132242 |
| TPM4 | tropomyosin 4 | -0.0949806 |
| NPSR1 | neuropeptide S receptor 1 | -0.0927485 |
| VCL | vinculin | -0.0893342 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0872307 |
| TNS4 | tensin 4 | -0.0858016 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0781697 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0734397 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0714903 |
| FHIT | fragile histidine triad | -0.0684303 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0566678 |
| RPS6 | ribosomal protein S6 | -0.0562868 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0551112 |
| POTEF | POTE ankyrin domain family, member F | -0.0547072 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0544083 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0541081 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0519623 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0497396 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0471591 |
| FOSL1 | FOS-like antigen 1 | -0.0455382 |
| PDLIM5 | PDZ and LIM domain 5 | -0.045127 |
| ACTG1 | actin gamma 1 | -0.0431897 |
| RPL9 | ribosomal protein L9 | -0.0405821 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0401187 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0399643 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0396993 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0388985 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.038639 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0385874 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0379972 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0369974 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0368716 |
| RAD51B | RAD51 paralog B | -0.0365504 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0360006 |
| HMGA1 | high mobility group AT-hook 1 | -0.0357246 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0353672 |
| FLNB | filamin B, beta | -0.0348571 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0340012 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0338786 |
| EGFR | epidermal growth factor receptor | -0.0338777 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.033141 |
| ONECUT3 | one cut homeobox 3 | -0.0330114 |
| FERMT1 | fermitin family member 1 | -0.0315785 |
| TXNIP | thioredoxin interacting protein | -0.0315505 |
| RPL21 | ribosomal protein L21 | -0.0314547 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0313453 |
| MUC17 | mucin 17, cell surface associated | -0.0313282 |
| TPM1 | tropomyosin 1 (alpha) | -0.0305177 |
| EGR1 | early growth response 1 | -0.0304581 |
| CALR | calreticulin | -0.0301044 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0294571 |
| NEBL | nebulette | -0.0292162 |
| RPL37A | ribosomal protein L37a | -0.0287926 |
| SMYD3 | SET and MYND domain containing 3 | -0.0285971 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0280951 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0277928 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0272331 |
| ABR | active BCR-related | -0.0272323 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0271684 |
| CCND1 | cyclin D1 | -0.0270552 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.027004 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0261145 |
| ITGB4 | integrin, beta 4 | -0.0255708 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0251465 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0245121 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0245036 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0243662 |
| PCDH9 | protocadherin 9 | -0.0241428 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0240681 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0239179 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0236422 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0230763 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0223333 |
| LSAMP | limbic system-associated membrane protein | -0.0222434 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.022199 |
| PBRM1 | polybromo 1 | -0.0221505 |
| WWOX | WW domain containing oxidoreductase | -0.0220504 |
| CADPS | Ca++-dependent secretion activator | -0.0220388 |
| MLEC | malectin | -0.0219916 |
| RPL23 | ribosomal protein L23 | -0.0219457 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0219257 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0218599 |
| LDHA | lactate dehydrogenase A | -0.0216836 |
| KRT19 | keratin 19, type I | -0.0216499 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0215808 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0214787 |
| MYO1D | myosin ID | -0.0209597 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0209562 |
| HM13 | histocompatibility (minor) 13 | -0.0208592 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0208104 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0207329 |
| ANXA2 | annexin A2 | -0.0206317 |
| CALB1 | calbindin 1, 28kDa | -0.0205795 |
| MECOM | MDS1 and EVI1 complex locus | -0.0204434 |
| PLIN2 | perilipin 2 | -0.0202244 |
| FAM120A | family with sequence similarity 120A | -0.0201239 |
