| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bexarotene_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.357739 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.290375 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.231432 |
| ACACA | acetyl-CoA carboxylase alpha | 0.134362 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.108187 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.10699 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.10663 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.101721 |
| HDAC9 | histone deacetylase 9 | 0.0849138 |
| EPHA4 | EPH receptor A4 | 0.0827729 |
| CANX | calnexin | 0.0792014 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0769274 |
| RUNX1 | runt-related transcription factor 1 | 0.0730326 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0697743 |
| EFNA5 | ephrin-A5 | 0.0673736 |
| EHBP1 | EH domain binding protein 1 | 0.0671189 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0648604 |
| TMEM135 | transmembrane protein 135 | 0.0621122 |
| RAI1 | retinoic acid induced 1 | 0.057231 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0561079 |
| PLK2 | polo-like kinase 2 | 0.0534276 |
| TNS3 | tensin 3 | 0.0524423 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0512237 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.049252 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0482185 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0461457 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0459639 |
| LOXL2 | lysyl oxidase-like 2 | 0.0459225 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0455317 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0451447 |
| CD44 | CD44 molecule (Indian blood group) | 0.0437687 |
| CALR | calreticulin | 0.0435994 |
| EXOC4 | exocyst complex component 4 | 0.0421327 |
| JUN | jun proto-oncogene | 0.0413322 |
| GOLGA4 | golgin A4 | 0.0404748 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0397475 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.038857 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0381992 |
| SEC24A | SEC24 family member A | 0.0381416 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0377667 |
| TMSB4X | thymosin beta 4, X-linked | 0.0377124 |
| PTK2 | protein tyrosine kinase 2 | 0.0375873 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0373218 |
| MYOF | myoferlin | 0.0370297 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0369008 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0347268 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0346805 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0339905 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0337809 |
| DENND1A | DENN/MADD domain containing 1A | 0.0332872 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0326709 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0322264 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0318268 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0314701 |
| RAD51B | RAD51 paralog B | 0.0308343 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0294161 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.029278 |
| SQSTM1 | sequestosome 1 | 0.0292096 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0290237 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0286323 |
| LRRC49 | leucine rich repeat containing 49 | 0.0281346 |
| FNIP1 | folliculin interacting protein 1 | 0.0279357 |
| SSH2 | slingshot protein phosphatase 2 | 0.0277527 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0276701 |
| HELZ | helicase with zinc finger | 0.0274518 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0272575 |
| WASF2 | WAS protein family, member 2 | 0.0268916 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0267004 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0265512 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0265242 |
| NBEAL1 | neurobeachin-like 1 | 0.0265047 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0264822 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0262686 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0256882 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0256772 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.0254473 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0250949 |
| HDAC8 | histone deacetylase 8 | 0.0249342 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0245507 |
| SMYD3 | SET and MYND domain containing 3 | 0.0243727 |
| RNF145 | ring finger protein 145 | 0.0241447 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0239781 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0238726 |
| CADM2 | cell adhesion molecule 2 | 0.0235346 |
| EGFR | epidermal growth factor receptor | 0.0235313 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0235139 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0235122 |
| LYST | lysosomal trafficking regulator | 0.0232061 |
| PHF21A | PHD finger protein 21A | 0.0230234 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0229045 |
| PGK1 | phosphoglycerate kinase 1 | 0.0227658 |
| SP100 | SP100 nuclear antigen | 0.0226307 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0223406 |
| TRERF1 | transcriptional regulating factor 1 | 0.0222613 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0222346 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0222064 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0219601 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0219563 |
| ATM | ATM serine/threonine kinase | 0.0212462 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0211875 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.169115 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0951166 |
| TXNRD1 | thioredoxin reductase 1 | -0.0915137 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0814057 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.081314 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0706073 |
| SPAG9 | sperm associated antigen 9 | -0.0668553 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0668005 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0647163 |
| POTEF | POTE ankyrin domain family, member F | -0.06099 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0604564 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0586151 |
| ACTG1 | actin gamma 1 | -0.0577529 |
| CENPF | centromere protein F, 350/400kDa | -0.0576469 |
| CAPRIN2 | caprin family member 2 | -0.0561238 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0552851 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0552798 |
| RPS6 | ribosomal protein S6 | -0.0505872 |
| MT1E | metallothionein 1E | -0.0504917 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0471692 |
| EMP1 | epithelial membrane protein 1 | -0.0459105 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.04541 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0437636 |
| KLF6 | Kruppel-like factor 6 | -0.0424919 |
| FERMT1 | fermitin family member 1 | -0.0423445 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0419446 |
| RPS2 | ribosomal protein S2 | -0.0405738 |
| MKI67 | marker of proliferation Ki-67 | -0.0400139 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0397767 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0390219 |
| NUP58 | nucleoporin 58 | -0.0371595 |
| MT1X | metallothionein 1X | -0.036747 |
| USP34 | ubiquitin specific peptidase 34 | -0.0365831 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0363576 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0358215 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0357868 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0354188 |
| RTN4 | reticulon 4 | -0.0346586 |
| VIM | vimentin | -0.0337592 |
| PDE10A | phosphodiesterase 10A | -0.033516 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0329153 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0328967 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0328748 |
| PRDX1 | peroxiredoxin 1 | -0.0325409 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0323152 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0323101 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0311775 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0304786 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0298687 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0297325 |
| CDCP1 | CUB domain containing protein 1 | -0.0296753 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0295261 |
| FLNB | filamin B, beta | -0.0290178 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0284978 |
| ZNF217 | zinc finger protein 217 | -0.0284579 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0284324 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.028035 |
| SON | SON DNA binding protein | -0.0280067 |
| RRM2 | ribonucleotide reductase M2 | -0.0278001 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0277241 |
| PYGB | phosphorylase, glycogen; brain | -0.0276437 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0276123 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0274293 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.026498 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0263391 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0262401 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0259934 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0258852 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0258177 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0257369 |
| RPS12 | ribosomal protein S12 | -0.0256653 |
| USP12 | ubiquitin specific peptidase 12 | -0.0253983 |
| RECQL | RecQ helicase-like | -0.0252258 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0250998 |
| BRD2 | bromodomain containing 2 | -0.0250208 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.025001 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0244914 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0244811 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0242688 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0241806 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0240002 |
| NCKAP1 | NCK-associated protein 1 | -0.023987 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0238938 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0234521 |
| GAN | gigaxonin | -0.0232468 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0228905 |
| RPL26 | ribosomal protein L26 | -0.0223804 |
| SEPTIN7 | septin 7 | -0.0223239 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.021773 |
| XPO1 | exportin 1 | -0.0213245 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -0.0212613 |
| SOCS6 | suppressor of cytokine signaling 6 | -0.0208555 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0208085 |
| RPL23 | ribosomal protein L23 | -0.0207684 |
| S100A11 | S100 calcium binding protein A11 | -0.0206991 |
| ANLN | anillin, actin binding protein | -0.0206886 |
| RPL38 | ribosomal protein L38 | -0.0206781 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0203537 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0201698 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0201503 |
