| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bexarotene_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | 0.0590195 |
| MCL1 | myeloid cell leukemia 1 | 0.0565709 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0529159 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0438669 |
| LMO7 | LIM domain 7 | 0.0434246 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0384382 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0356879 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.034649 |
| USP53 | ubiquitin specific peptidase 53 | 0.0313635 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0308775 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0292246 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0285678 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0280131 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.026482 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0263687 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0261297 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0247926 |
| SLTM | SAFB-like, transcription modulator | 0.0243039 |
| FNIP1 | folliculin interacting protein 1 | 0.0240291 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0238441 |
| ASPH | aspartate beta-hydroxylase | 0.0237733 |
| SDC4 | syndecan 4 | 0.0235347 |
| ENSA | endosulfine alpha | 0.0222798 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0221615 |
| MYO1D | myosin ID | 0.021759 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0211332 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0205466 |
| RASA2 | RAS p21 protein activator 2 | 0.020388 |
| SCEL | sciellin | 0.0201748 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0199966 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0198781 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0198633 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0197355 |
| OSMR | oncostatin M receptor | 0.0196885 |
| LAMA4 | laminin, alpha 4 | 0.0195955 |
| OXSR1 | oxidative stress responsive 1 | 0.0188529 |
| BMP6 | bone morphogenetic protein 6 | 0.0187996 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0187401 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0185381 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0183676 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0183042 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0181955 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0181933 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0180129 |
| EFNA5 | ephrin-A5 | 0.0179434 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0178889 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0176234 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0173919 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0171507 |
| VMP1 | vacuole membrane protein 1 | 0.0171415 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0169943 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0169846 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0169222 |
| USP34 | ubiquitin specific peptidase 34 | 0.0165788 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0164031 |
| DSPP | dentin sialophosphoprotein | 0.0157624 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0155901 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0151972 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0151316 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0150423 |
| MYO5B | myosin VB | 0.0148226 |
| ANXA1 | annexin A1 | 0.0144794 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0140945 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0140732 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0139375 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0138188 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0137663 |
| SPAG9 | sperm associated antigen 9 | 0.0137501 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0134484 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0134433 |
| SEPTIN10 | septin 10 | 0.0132622 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0132578 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0132114 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0131042 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0128094 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0127608 |
| ITSN2 | intersectin 2 | 0.0126128 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0122973 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0121237 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0121209 |
| FDPS | farnesyl diphosphate synthase | 0.0121005 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0118649 |
| MYO6 | myosin VI | 0.0117901 |
| GPATCH2L | G patch domain containing 2-like | 0.0117448 |
| CYTH1 | cytohesin 1 | 0.0116414 |
| FMNL2 | formin-like 2 | 0.0115581 |
| JMJD1C | jumonji domain containing 1C | 0.0115234 |
| RAI14 | retinoic acid induced 14 | 0.0113984 |
| RNF149 | ring finger protein 149 | 0.0113491 |
| EP300 | E1A binding protein p300 | 0.0112216 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.011038 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0110041 |
| RCOR1 | REST corepressor 1 | 0.0108702 |
| LIPH | lipase, member H | 0.0107669 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0107336 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0107131 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0106326 |
| RB1 | retinoblastoma 1 | 0.0104502 |
| MYO1E | myosin IE | 0.0104367 |
| HMGA2 | high mobility group AT-hook 2 | 0.0104326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.217199 |
| TMSB10 | thymosin beta 10 | -0.109255 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.090209 |
| NDRG1 | N-myc downstream regulated 1 | -0.0759682 |
| FTL | ferritin, light polypeptide | -0.0668564 |
| PKM | pyruvate kinase, muscle | -0.0662966 |
| MT2A | metallothionein 2A | -0.0641237 |
| TXNRD1 | thioredoxin reductase 1 | -0.0589043 |
| RPS3 | ribosomal protein S3 | -0.0583937 |
| PTMA | prothymosin, alpha | -0.055793 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0507094 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0491601 |
| SEC61G | Sec61 gamma subunit | -0.0474142 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0464307 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0463354 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.042237 |
| RPL35A | ribosomal protein L35a | -0.0420948 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0413273 |
| RPS6 | ribosomal protein S6 | -0.0413161 |
| RPLP1 | ribosomal protein, large, P1 | -0.0408569 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0395003 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0389731 |
| RPS25 | ribosomal protein S25 | -0.0375986 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0361154 |
| MYOF | myoferlin | -0.0351323 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0347584 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0341136 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0334585 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0321143 |
| RPS8 | ribosomal protein S8 | -0.0313816 |
| MORF4L2 | mortality factor 4 like 2 | -0.0312382 |
| GRAMD1B | GRAM domain containing 1B | -0.0309796 |
| H1-0 | H1.0 linker histone | -0.0309335 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.030523 |
| CST3 | cystatin C | -0.0303708 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0301338 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0293066 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0286055 |
| RPL37A | ribosomal protein L37a | -0.0285727 |
| RPS24 | ribosomal protein S24 | -0.028405 |
| TES | testin LIM domain protein | -0.0276325 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0273074 |
| RPS12 | ribosomal protein S12 | -0.0263939 |
| HYOU1 | hypoxia up-regulated 1 | -0.0262974 |
| ENO1 | enolase 1, (alpha) | -0.0262298 |
| RPL34 | ribosomal protein L34 | -0.0262204 |
| EGR1 | early growth response 1 | -0.0261976 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0260379 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0253183 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.024741 |
| UVRAG | UV radiation resistance associated | -0.0245367 |
| RPLP0 | ribosomal protein, large, P0 | -0.0244964 |
| HELZ | helicase with zinc finger | -0.024218 |
| KRT7 | keratin 7, type II | -0.0237598 |
| RACK1 | receptor for activated C kinase 1 | -0.023628 |
| RPL30 | ribosomal protein L30 | -0.0232899 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0232427 |
| RPL23 | ribosomal protein L23 | -0.0230049 |
| S100A9 | S100 calcium binding protein A9 | -0.022421 |
| RPS21 | ribosomal protein S21 | -0.0218121 |
| RPL19 | ribosomal protein L19 | -0.0215822 |
| S100A10 | S100 calcium binding protein A10 | -0.021514 |
| RPS23 | ribosomal protein S23 | -0.0214976 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0214778 |
| CANX | calnexin | -0.0214656 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0213132 |
| LDHA | lactate dehydrogenase A | -0.0212988 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0212683 |
| RPL5 | ribosomal protein L5 | -0.0208604 |
| HDLBP | high density lipoprotein binding protein | -0.0208538 |
| HMGA1 | high mobility group AT-hook 1 | -0.0207259 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0206779 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0206635 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0206029 |
| TPI1 | triosephosphate isomerase 1 | -0.020514 |
| EGFR | epidermal growth factor receptor | -0.0203741 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0203674 |
| B2M | beta-2-microglobulin | -0.0202337 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0198235 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0197723 |
| RPS29 | ribosomal protein S29 | -0.019725 |
| BBX | bobby sox homolog (Drosophila) | -0.0195053 |
| ZNF292 | zinc finger protein 292 | -0.0193289 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.019244 |
| RPL8 | ribosomal protein L8 | -0.0190853 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0189955 |
| RPL37 | ribosomal protein L37 | -0.0189384 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0186352 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0183982 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0183916 |
| RPS14 | ribosomal protein S14 | -0.0182921 |
| PCBP2 | poly(rC) binding protein 2 | -0.0181395 |
| PGK1 | phosphoglycerate kinase 1 | -0.0181043 |
| TMEM165 | transmembrane protein 165 | -0.0180993 |
| RPS19 | ribosomal protein S19 | -0.0180008 |
| TKT | transketolase | -0.0178463 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0176369 |
| EMP1 | epithelial membrane protein 1 | -0.017379 |
| CALR | calreticulin | -0.0171994 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0171105 |
