| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bexarotene_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.164537 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.151835 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.113284 |
| GOLGA4 | golgin A4 | 0.106875 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0877706 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.076964 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0733471 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0687139 |
| SMAD3 | SMAD family member 3 | 0.0643314 |
| RBM39 | RNA binding motif protein 39 | 0.0612304 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0602347 |
| RARB | retinoic acid receptor, beta | 0.0567999 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0563504 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0526395 |
| VMP1 | vacuole membrane protein 1 | 0.0503449 |
| OGA | O-GlcNAcase | 0.0486486 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0486435 |
| FAM13A | family with sequence similarity 13, member A | 0.0458142 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0456878 |
| PCBP2 | poly(rC) binding protein 2 | 0.0429726 |
| USP34 | ubiquitin specific peptidase 34 | 0.0422402 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0420833 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0418549 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0404607 |
| FAM107B | family with sequence similarity 107, member B | 0.0403625 |
| SIK3 | SIK family kinase 3 | 0.0392973 |
| COG5 | component of oligomeric golgi complex 5 | 0.0392851 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0388757 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0383628 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0380515 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0374776 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0369955 |
| SBF2 | SET binding factor 2 | 0.0367673 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0366117 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0364744 |
| SEC24A | SEC24 family member A | 0.0363184 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0354837 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0350604 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0349294 |
| ADD3 | adducin 3 (gamma) | 0.0332642 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0329551 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0328533 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0324161 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0322383 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0320406 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0320231 |
| FRMD5 | FERM domain containing 5 | 0.0317865 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0317037 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0314406 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.031303 |
| ETNK1 | ethanolamine kinase 1 | 0.0305228 |
| COPA | coatomer protein complex, subunit alpha | 0.0304812 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0303806 |
| EXOC6B | exocyst complex component 6B | 0.0298366 |
| SRP54 | signal recognition particle 54kDa | 0.0297479 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0294977 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0293459 |
| FAM3C | family with sequence similarity 3, member C | 0.029342 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0293065 |
| AHR | aryl hydrocarbon receptor | 0.0292262 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0287994 |
| HELZ | helicase with zinc finger | 0.0285239 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0280854 |
| NCOA7 | nuclear receptor coactivator 7 | 0.028052 |
| NGLY1 | N-glycanase 1 | 0.0279038 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0278363 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0274207 |
| YME1L1 | YME1-like 1 ATPase | 0.0270519 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0269642 |
| FBXO32 | F-box protein 32 | 0.0269615 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0267948 |
| PRELID2 | PRELI domain containing 2 | 0.0265037 |
| NBAS | neuroblastoma amplified sequence | 0.0263687 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0262026 |
| SPAG9 | sperm associated antigen 9 | 0.0261879 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0260978 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0258283 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0257044 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0254591 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0251565 |
| RAB1A | RAB1A, member RAS oncogene family | 0.024842 |
| EEA1 | early endosome antigen 1 | 0.024831 |
| RNF145 | ring finger protein 145 | 0.0247776 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0247085 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0246952 |
| SUCO | SUN domain containing ossification factor | 0.0244554 |
| RASA2 | RAS p21 protein activator 2 | 0.0244103 |
| SCFD1 | sec1 family domain containing 1 | 0.0241809 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0241442 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0241381 |
| NAV2 | neuron navigator 2 | 0.0237905 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0237492 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0235277 |
| HDAC9 | histone deacetylase 9 | 0.0234841 |
| FOXO3 | forkhead box O3 | 0.023475 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0233312 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0232376 |
| SETD5 | SET domain containing 5 | 0.0231215 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0227752 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0226743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.192085 |
| VIM | vimentin | -0.165969 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155986 |
| TMSB10 | thymosin beta 10 | -0.145303 |
| CDH13 | cadherin 13 | -0.143441 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.140811 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.114631 |
| LOX | lysyl oxidase | -0.112906 |
| HMGA2 | high mobility group AT-hook 2 | -0.109688 |
| NRG1 | neuregulin 1 | -0.0977989 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0914908 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0704283 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0699782 |
| MTSS1 | metastasis suppressor 1 | -0.0688497 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.065705 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0644693 |
| GLCCI1 | glucocorticoid induced 1 | -0.0643355 |
| CD44 | CD44 molecule (Indian blood group) | -0.0640868 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0639478 |
| ANTXR2 | anthrax toxin receptor 2 | -0.061823 |
| FTL | ferritin, light polypeptide | -0.0601416 |
| NDRG1 | N-myc downstream regulated 1 | -0.057039 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0567314 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0554068 |
| RPLP1 | ribosomal protein, large, P1 | -0.0519964 |
| PTMA | prothymosin, alpha | -0.0501417 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0501391 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0500723 |
| S100A6 | S100 calcium binding protein A6 | -0.0480708 |
| AHNAK | AHNAK nucleoprotein | -0.0469311 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0452891 |
| CLMP | CXADR-like membrane protein | -0.044952 |
| MEF2A | myocyte enhancer factor 2A | -0.0448396 |
| ASPH | aspartate beta-hydroxylase | -0.0440926 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0437879 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0428246 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0415108 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0414957 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0409104 |
| RPL35A | ribosomal protein L35a | -0.0402159 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0402103 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0398791 |
| RPS6 | ribosomal protein S6 | -0.0398332 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0389728 |
| FBN1 | fibrillin 1 | -0.03889 |
| GLIS3 | GLIS family zinc finger 3 | -0.0382261 |
| PKM | pyruvate kinase, muscle | -0.0379802 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0377981 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0377124 |
| STC1 | stanniocalcin 1 | -0.0371813 |
| ENO1 | enolase 1, (alpha) | -0.0361367 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0353529 |
| RPS19 | ribosomal protein S19 | -0.0344778 |
| HMGA1 | high mobility group AT-hook 1 | -0.0340704 |
| NAV1 | neuron navigator 1 | -0.033993 |
| RPS8 | ribosomal protein S8 | -0.0335943 |
| CDCP1 | CUB domain containing protein 1 | -0.0334123 |
| S100A10 | S100 calcium binding protein A10 | -0.0334024 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0328466 |
| IFI44L | interferon-induced protein 44-like | -0.0325579 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0318533 |
| RPL34 | ribosomal protein L34 | -0.0310439 |
| CUX1 | cut-like homeobox 1 | -0.0306659 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0303212 |
| TMSB4X | thymosin beta 4, X-linked | -0.0303183 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0302261 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0301813 |
| IL1B | interleukin 1, beta | -0.0299943 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0299546 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.029822 |
| BMERB1 | bMERB domain containing 1 | -0.0298069 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0296947 |
| SEPTIN9 | septin 9 | -0.0295883 |
| SYT1 | synaptotagmin I | -0.0294924 |
| RPL36 | ribosomal protein L36 | -0.0294104 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.028657 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282752 |
| PRRX1 | paired related homeobox 1 | -0.0282071 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282015 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0279357 |
| RPL37A | ribosomal protein L37a | -0.0277842 |
| RPS12 | ribosomal protein S12 | -0.027702 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0271617 |
| RNF213 | ring finger protein 213 | -0.0270507 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0269335 |
| PRSS23 | protease, serine, 23 | -0.0268413 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0267538 |
| SP100 | SP100 nuclear antigen | -0.0266965 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0265743 |
| RPL31 | ribosomal protein L31 | -0.0262873 |
| OXR1 | oxidation resistance 1 | -0.026194 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0261216 |
| EGR1 | early growth response 1 | -0.0260869 |
| PRKCA | protein kinase C, alpha | -0.0260204 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0257674 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0257378 |
| RPS25 | ribosomal protein S25 | -0.0257286 |
| CA12 | carbonic anhydrase XII | -0.0256545 |
| ANKRD28 | ankyrin repeat domain 28 | -0.025639 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0253071 |
