| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bexarotene_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.21617 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.146067 |
| TXNRD1 | thioredoxin reductase 1 | 0.134621 |
| FNDC3B | fibronectin type III domain containing 3B | 0.12988 |
| TSC22D2 | TSC22 domain family, member 2 | 0.103824 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.10132 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0951793 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0937319 |
| ANXA2 | annexin A2 | 0.0933435 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0744723 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0716104 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0680098 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0662128 |
| KYNU | kynureninase | 0.0650881 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0642382 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0621123 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0588669 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0584437 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0576763 |
| VMP1 | vacuole membrane protein 1 | 0.0568511 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0547438 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0545297 |
| PHF21A | PHD finger protein 21A | 0.0543458 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0541779 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.053027 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0524489 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0520472 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0510295 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0509357 |
| B2M | beta-2-microglobulin | 0.0507872 |
| MT2A | metallothionein 2A | 0.0499982 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0493502 |
| MORF4L2 | mortality factor 4 like 2 | 0.0491787 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0485113 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0484735 |
| CADM1 | cell adhesion molecule 1 | 0.0483042 |
| RPL12 | ribosomal protein L12 | 0.0476397 |
| SDC4 | syndecan 4 | 0.0472776 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0472718 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0471546 |
| PGK1 | phosphoglycerate kinase 1 | 0.0467571 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0466936 |
| GRAMD1B | GRAM domain containing 1B | 0.0456372 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0451531 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.044812 |
| RASA2 | RAS p21 protein activator 2 | 0.0447197 |
| PTK2 | protein tyrosine kinase 2 | 0.0445965 |
| RBM26 | RNA binding motif protein 26 | 0.0445305 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0442116 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0439164 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0433046 |
| OLA1 | Obg-like ATPase 1 | 0.0432959 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0429824 |
| SUCO | SUN domain containing ossification factor | 0.042396 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0421639 |
| RPL23 | ribosomal protein L23 | 0.0417061 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0408706 |
| GDNF | glial cell derived neurotrophic factor | 0.0399132 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0397932 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.039712 |
| S100A9 | S100 calcium binding protein A9 | 0.0394733 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0390411 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0388612 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0386074 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0383687 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0383392 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0382894 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0381066 |
| RPS13 | ribosomal protein S13 | 0.0379868 |
| TPD52 | tumor protein D52 | 0.0379193 |
| SMAD3 | SMAD family member 3 | 0.0374445 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0367404 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0365593 |
| COG5 | component of oligomeric golgi complex 5 | 0.0364319 |
| NCKAP1 | NCK-associated protein 1 | 0.0360395 |
| CUL3 | cullin 3 | 0.0358523 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0357317 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0355832 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.035338 |
| RNF145 | ring finger protein 145 | 0.0353114 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0352658 |
| SMYD3 | SET and MYND domain containing 3 | 0.0351692 |
| RBM39 | RNA binding motif protein 39 | 0.0351559 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0346219 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0343256 |
| RPL34 | ribosomal protein L34 | 0.0342914 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0342405 |
| DTNA | dystrobrevin, alpha | 0.033252 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0332082 |
| STC1 | stanniocalcin 1 | 0.0330918 |
| USP3 | ubiquitin specific peptidase 3 | 0.0330368 |
| ZNF644 | zinc finger protein 644 | 0.0328196 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0325697 |
| APP | amyloid beta (A4) precursor protein | 0.0322657 |
| RAI14 | retinoic acid induced 14 | 0.0319562 |
| CD44 | CD44 molecule (Indian blood group) | 0.0317528 |
| ATP13A3 | ATPase type 13A3 | 0.0316522 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0310719 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0310271 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0308459 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.184961 |
| LMO7 | LIM domain 7 | -0.144669 |
| MUC16 | mucin 16, cell surface associated | -0.144414 |
| GRB10 | growth factor receptor-bound protein 10 | -0.103429 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0914572 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0893265 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0872998 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0863478 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0811308 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0805533 |
| MYO1E | myosin IE | -0.0743736 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0732568 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0725622 |
| SRPK2 | SRSF protein kinase 2 | -0.0714677 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0669911 |
| PERP | PERP, TP53 apoptosis effector | -0.0648434 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0640505 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0638231 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0629792 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0624199 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0618447 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0607999 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0564277 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0561946 |
| MYO5B | myosin VB | -0.0557218 |
| VGF | VGF nerve growth factor inducible | -0.0536756 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0536044 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0535206 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0534868 |
| OSMR | oncostatin M receptor | -0.0522235 |
| JUP | junction plakoglobin | -0.0519562 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0504516 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0502227 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0501513 |
| AK1 | adenylate kinase 1 | -0.0497561 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0491084 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.049019 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0484666 |
| RPLP0 | ribosomal protein, large, P0 | -0.0471585 |
| NHSL1 | NHS-like 1 | -0.04672 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0458758 |
| RORA | RAR-related orphan receptor A | -0.0450692 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0446648 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0444803 |
| EGFR | epidermal growth factor receptor | -0.0442558 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0440736 |
| GPC6 | glypican 6 | -0.0427624 |
| ATOSA | atos homolog A | -0.0420233 |
| ACTN4 | actinin, alpha 4 | -0.0419499 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0418747 |
| INSIG1 | insulin induced gene 1 | -0.0418448 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0413479 |
| NPTN | neuroplastin | -0.0412638 |
| NEK7 | NIMA-related kinase 7 | -0.040191 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0399241 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0398018 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0395346 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0393938 |
| RIGI | RNA sensor RIG-I | -0.039349 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0389122 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0388908 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0387873 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0385152 |
| ZNF292 | zinc finger protein 292 | -0.0383442 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0381629 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0380607 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0380196 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0379324 |
| RUNX1 | runt-related transcription factor 1 | -0.0377226 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0376587 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.037197 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0369327 |
| STRN | striatin, calmodulin binding protein | -0.0369063 |
| ASPH | aspartate beta-hydroxylase | -0.0365559 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0358493 |
| CUX1 | cut-like homeobox 1 | -0.0358171 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0356277 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0356275 |
| PDS5A | PDS5 cohesin associated factor A | -0.0354337 |
| FRYL | FRY-like | -0.035335 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0351282 |
| CMIP | c-Maf inducing protein | -0.0349622 |
| WAPL | WAPL cohesin release factor | -0.0348959 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0346513 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0342368 |
| AHNAK | AHNAK nucleoprotein | -0.0333103 |
| USP33 | ubiquitin specific peptidase 33 | -0.0331603 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0328313 |
| RNF213 | ring finger protein 213 | -0.0325238 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0324192 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0320508 |
| ATXN1 | ataxin 1 | -0.0316129 |
| EGR1 | early growth response 1 | -0.0315254 |
| TJP1 | tight junction protein 1 | -0.0312387 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0311892 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0310764 |
| FMN1 | formin 1 | -0.0310364 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0310205 |
| LAMB3 | laminin, beta 3 | -0.0307129 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0305201 |
