| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bexarotene_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.406302 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.219163 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.122487 |
| COPA | coatomer protein complex, subunit alpha | 0.0982752 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0842373 |
| VMP1 | vacuole membrane protein 1 | 0.0790978 |
| TXNRD1 | thioredoxin reductase 1 | 0.0781677 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0724574 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0592312 |
| PGK1 | phosphoglycerate kinase 1 | 0.0559186 |
| SMAD3 | SMAD family member 3 | 0.0545407 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0538543 |
| RSF1 | remodeling and spacing factor 1 | 0.0535426 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0513177 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0496718 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.049497 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0477963 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0468205 |
| YBX3 | Y box binding protein 3 | 0.045558 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0455453 |
| EHBP1 | EH domain binding protein 1 | 0.0444895 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0443537 |
| ERBIN | erbb2 interacting protein | 0.0435953 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0428707 |
| ATXN2 | ataxin 2 | 0.0428013 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0427443 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0424681 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.041546 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0408674 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0404999 |
| KRT18 | keratin 18, type I | 0.0388582 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0378267 |
| PHF21A | PHD finger protein 21A | 0.037811 |
| VCL | vinculin | 0.0376326 |
| CANX | calnexin | 0.0374929 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0365532 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0356552 |
| DENND1A | DENN/MADD domain containing 1A | 0.0355541 |
| TPM3 | tropomyosin 3 | 0.0346807 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0346268 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0344914 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0344811 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.034276 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0341538 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0326253 |
| MCL1 | myeloid cell leukemia 1 | 0.0326146 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0325583 |
| ARF4 | ADP-ribosylation factor 4 | 0.0324601 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0319961 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0319872 |
| NBEAL1 | neurobeachin-like 1 | 0.0319405 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0319157 |
| UBXN7 | UBX domain protein 7 | 0.031721 |
| CDK13 | cyclin-dependent kinase 13 | 0.0316976 |
| GPHN | gephyrin | 0.0315196 |
| DIAPH2 | diaphanous-related formin 2 | 0.0311079 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0309657 |
| SBF2 | SET binding factor 2 | 0.0305912 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0305185 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0304291 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0301209 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0300764 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0300757 |
| CEP250 | centrosomal protein 250kDa | 0.0299371 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0299321 |
| WASF2 | WAS protein family, member 2 | 0.0297958 |
| SEC24A | SEC24 family member A | 0.0297083 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0296675 |
| TPM2 | tropomyosin 2 (beta) | 0.0292878 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0288859 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0285648 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0278407 |
| HDGF | hepatoma-derived growth factor | 0.0278266 |
| TMEM14B | transmembrane protein 14B | 0.0277843 |
| GOLGA4 | golgin A4 | 0.027137 |
| VCP | valosin containing protein | 0.027111 |
| PYGL | phosphorylase, glycogen, liver | 0.0269818 |
| NABP1 | nucleic acid binding protein 1 | 0.026839 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit | 0.0267809 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0267689 |
| TMEM39A | transmembrane protein 39A | 0.0262774 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0262422 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0261796 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0258363 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0256188 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0255267 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0253166 |
| XPOT | exportin, tRNA | 0.0247275 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0247159 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247149 |
| PARD3 | par-3 family cell polarity regulator | 0.0245896 |
| WDR3 | WD repeat domain 3 | 0.0245345 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0244895 |
| ENSA | endosulfine alpha | 0.0243767 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0238115 |
| ZNF638 | zinc finger protein 638 | 0.0237454 |
| USP34 | ubiquitin specific peptidase 34 | 0.0236245 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.023579 |
| R3HDM1 | R3H domain containing 1 | 0.0235558 |
| NFIA | nuclear factor I/A | 0.0233372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0897581 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0726987 |
| RPS2 | ribosomal protein S2 | -0.0507416 |
| RBM39 | RNA binding motif protein 39 | -0.0501469 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0500015 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0498496 |
| RPL26 | ribosomal protein L26 | -0.0496979 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0476858 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0466741 |
| CENPF | centromere protein F, 350/400kDa | -0.0446876 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.043788 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.042013 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0414998 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.041315 |
| PDE10A | phosphodiesterase 10A | -0.0407935 |
| RPS29 | ribosomal protein S29 | -0.0397164 |
| RPS12 | ribosomal protein S12 | -0.039282 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0370835 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0368133 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0361163 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0352899 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0351083 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0332249 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0320826 |
| RTN4 | reticulon 4 | -0.0316515 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0316123 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0311829 |
| RPLP1 | ribosomal protein, large, P1 | -0.030803 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0300647 |
| CCND2 | cyclin D2 | -0.0291324 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0289602 |
| RPL23 | ribosomal protein L23 | -0.0289262 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0286256 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0285835 |
| ZFR | zinc finger RNA binding protein | -0.0284923 |
| RRM2 | ribonucleotide reductase M2 | -0.0282922 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0280596 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0278878 |
| RBM33 | RNA binding motif protein 33 | -0.0278837 |
| RPL36 | ribosomal protein L36 | -0.0278804 |
| ACTG1 | actin gamma 1 | -0.027753 |
| WWOX | WW domain containing oxidoreductase | -0.0276513 |
| RPS6 | ribosomal protein S6 | -0.0275793 |
| SEPTIN7 | septin 7 | -0.0269568 |
| RPL9 | ribosomal protein L9 | -0.0267711 |
| E2F3 | E2F transcription factor 3 | -0.0266772 |
| STK4 | serine/threonine kinase 4 | -0.0266544 |
| RPL38 | ribosomal protein L38 | -0.0265964 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0264815 |
| POTEF | POTE ankyrin domain family, member F | -0.026477 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.026409 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0262027 |
| LATS2 | large tumor suppressor kinase 2 | -0.0260522 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0254594 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0254485 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0253562 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0252545 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0251946 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0250918 |
| IGF2 | insulin-like growth factor 2 | -0.0250711 |
| RGS20 | regulator of G-protein signaling 20 | -0.0247387 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0246744 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0244224 |
| TUBA1B | tubulin, alpha 1b | -0.0244196 |
| BMP5 | bone morphogenetic protein 5 | -0.0244054 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0243463 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0242703 |
| AGBL4 | ATP/GTP binding protein-like 4 | -0.0242411 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0241293 |
| EGR1 | early growth response 1 | -0.0240188 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0239724 |
| RPL5 | ribosomal protein L5 | -0.0238898 |
| TWF1 | twinfilin actin binding protein 1 | -0.0236271 |
| FERMT2 | fermitin family member 2 | -0.0233701 |
| GEN1 | GEN1 Holliday junction 5' flap endonuclease | -0.0233282 |
| RPL7 | ribosomal protein L7 | -0.0231745 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0225784 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0225758 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0224959 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0223489 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0222402 |
| RPS10 | ribosomal protein S10 | -0.0219046 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0217214 |
| IPO7 | importin 7 | -0.0213145 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0212301 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0209768 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0209368 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0208689 |
| ZNF207 | zinc finger protein 207 | -0.0206822 |
| CCDC91 | coiled-coil domain containing 91 | -0.0205827 |
| RPS15 | ribosomal protein S15 | -0.0205512 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0204293 |
| FLNA | filamin A, alpha | -0.020424 |
| TJP1 | tight junction protein 1 | -0.0204062 |
| NUP205 | nucleoporin 205kDa | -0.0203172 |
| DEK | DEK proto-oncogene | -0.0202261 |
| HMGA1 | high mobility group AT-hook 1 | -0.0201316 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0200289 |
| GNAS | GNAS complex locus | -0.0200234 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0200159 |
