| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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190 genes differentially expressed following the Bexarotene_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.128051 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.111551 |
| RPS6 | ribosomal protein S6 | 0.109723 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.10763 |
| PGK1 | phosphoglycerate kinase 1 | 0.107196 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102101 |
| GOLGA4 | golgin A4 | 0.101565 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0982881 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0915423 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0892808 |
| EZR | ezrin | 0.0872156 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0856582 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0817742 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.081531 |
| FMN1 | formin 1 | 0.0786113 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0768928 |
| FRMD5 | FERM domain containing 5 | 0.0763994 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0730378 |
| ANXA2 | annexin A2 | 0.0722145 |
| USP34 | ubiquitin specific peptidase 34 | 0.0718507 |
| PTK2 | protein tyrosine kinase 2 | 0.0698205 |
| RNF145 | ring finger protein 145 | 0.0693323 |
| ENO1 | enolase 1, (alpha) | 0.0692869 |
| FTL | ferritin, light polypeptide | 0.0691195 |
| MSI2 | musashi RNA-binding protein 2 | 0.0675939 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0668942 |
| RUNX1 | runt-related transcription factor 1 | 0.0667657 |
| IGF2 | insulin-like growth factor 2 | 0.0652814 |
| ZNF292 | zinc finger protein 292 | 0.0644415 |
| MTDH | metadherin | 0.0643547 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0631201 |
| FNIP1 | folliculin interacting protein 1 | 0.0618864 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0617857 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0616134 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0579196 |
| GNAS | GNAS complex locus | 0.0559446 |
| SETD2 | SET domain containing 2 | 0.0553909 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0552534 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.055234 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0550834 |
| SYT1 | synaptotagmin I | 0.0548389 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0545129 |
| ANKRD12 | ankyrin repeat domain 12 | 0.053842 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.050491 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0494911 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0486914 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0476734 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0475952 |
| TPD52 | tumor protein D52 | 0.0470126 |
| RBM39 | RNA binding motif protein 39 | 0.046561 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0455773 |
| ZNF638 | zinc finger protein 638 | 0.0436124 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0433463 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0419475 |
| ETNK1 | ethanolamine kinase 1 | 0.0416169 |
| MT2A | metallothionein 2A | 0.0393017 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0388329 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0384549 |
| NBAS | neuroblastoma amplified sequence | 0.037557 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0363381 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.035586 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0351945 |
| RBM25 | RNA binding motif protein 25 | 0.0351938 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0347385 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0338624 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0333331 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321788 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0297162 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0295099 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0293868 |
| HELZ | helicase with zinc finger | 0.0290918 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0272592 |
| JMJD1C | jumonji domain containing 1C | 0.0270891 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0253631 |
| MEF2A | myocyte enhancer factor 2A | 0.0242124 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0224029 |
| ACTG1 | actin gamma 1 | 0.0214925 |
| APP | amyloid beta (A4) precursor protein | 0.0211319 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0210674 |
| PTMA | prothymosin, alpha | 0.0210278 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0196504 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0193378 |
| TENM3 | teneurin transmembrane protein 3 | 0.0182889 |
| OGA | O-GlcNAcase | 0.017562 |
| GLG1 | golgi glycoprotein 1 | 0.0171873 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0167858 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0164131 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.013331 |
| PRELID2 | PRELI domain containing 2 | 0.0130422 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0115019 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0084482 |
| SMAD3 | SMAD family member 3 | 0.00796174 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00776422 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.00337928 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.00129718 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 1.28163E-4 |
| CUX1 | cut-like homeobox 1 | 3.25178E-5 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.276565 |
| EFNA5 | ephrin-A5 | -0.236004 |
| PDE10A | phosphodiesterase 10A | -0.215745 |
| RORA | RAR-related orphan receptor A | -0.169201 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.152529 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.129054 |
| ASPH | aspartate beta-hydroxylase | -0.123226 |
| GPC6 | glypican 6 | -0.104758 |
| FN1 | fibronectin 1 | -0.0858308 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0838944 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0802878 |
| MYO1E | myosin IE | -0.0798808 |
| PCBP3 | poly(rC) binding protein 3 | -0.0797924 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0774456 |
| VCL | vinculin | -0.0748089 |
| EGFR | epidermal growth factor receptor | -0.0702008 |
| CDH13 | cadherin 13 | -0.0667554 |
| PRKCA | protein kinase C, alpha | -0.0633237 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0631737 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0613329 |
| ATXN1 | ataxin 1 | -0.059703 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0583426 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0527854 |
| SMYD3 | SET and MYND domain containing 3 | -0.052607 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0518354 |
| DST | dystonin | -0.0504303 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0500489 |
| NHSL1 | NHS-like 1 | -0.0464324 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0457245 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.045722 |
| SETD5 | SET domain containing 5 | -0.0441594 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0431081 |
| FLNB | filamin B, beta | -0.0430727 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0424551 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0417519 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0395121 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0394221 |
| MYOF | myoferlin | -0.0393107 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0380642 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0374253 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0366364 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0360958 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0357787 |
| RAD51B | RAD51 paralog B | -0.0344784 |
| STAG2 | stromal antigen 2 | -0.034028 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0333054 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0330687 |
| BPTF | bromodomain PHD finger transcription factor | -0.031535 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0313742 |
| FAM13A | family with sequence similarity 13, member A | -0.0312527 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0299926 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.02666 |
| NAV2 | neuron navigator 2 | -0.0261366 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0260755 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0251059 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0244233 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0239744 |
| EGR1 | early growth response 1 | -0.0239639 |
| CMIP | c-Maf inducing protein | -0.0234619 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0231272 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0220168 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0216916 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0209458 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.020381 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0200165 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0185781 |
| PARD3 | par-3 family cell polarity regulator | -0.0182637 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0171201 |
| VIM | vimentin | -0.0170521 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0148225 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0147412 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0144876 |
| VMP1 | vacuole membrane protein 1 | -0.0138742 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0136926 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0136785 |
| MCL1 | myeloid cell leukemia 1 | -0.0133597 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0119728 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0112857 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0110728 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0105261 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0098687 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.00958282 |
| NDRG1 | N-myc downstream regulated 1 | -0.0089138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00737308 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00629059 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00626053 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0047422 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00344281 |
| USP15 | ubiquitin specific peptidase 15 | -0.00132394 |
| INTS6 | integrator complex subunit 6 | -0.00110411 |
| HDLBP | high density lipoprotein binding protein | -7.89355E-4 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -3.43685E-4 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -3.42351E-4 |
