| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bexarotene_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.0492645 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0464552 |
| ZNF292 | zinc finger protein 292 | 0.0433186 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0415903 |
| USP3 | ubiquitin specific peptidase 3 | 0.0324863 |
| RHEB | Ras homolog enriched in brain | 0.0301453 |
| PDGFC | platelet derived growth factor C | 0.0264068 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0249235 |
| RYBP | RING1 and YY1 binding protein | 0.0239131 |
| CDC73 | cell division cycle 73 | 0.0236672 |
| QKI | QKI, KH domain containing, RNA binding | 0.0234618 |
| HMGB2 | high mobility group box 2 | 0.0234401 |
| HDAC9 | histone deacetylase 9 | 0.0233936 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0232762 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0227777 |
| NCKAP1 | NCK-associated protein 1 | 0.022493 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0215997 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0213449 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0212547 |
| YAP1 | Yes-associated protein 1 | 0.0210368 |
| HBP1 | HMG-box transcription factor 1 | 0.0207913 |
| GASK1B | golgi associated kinase 1B | 0.0203089 |
| TMSB4X | thymosin beta 4, X-linked | 0.0188148 |
| USP12 | ubiquitin specific peptidase 12 | 0.0186971 |
| MTF2 | metal response element binding transcription factor 2 | 0.0186357 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0183961 |
| LCA5 | Leber congenital amaurosis 5 | 0.0183006 |
| DMXL1 | Dmx-like 1 | 0.0182814 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0182246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0180995 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0179357 |
| MEMO1 | mediator of cell motility 1 | 0.0176676 |
| MATR3 | matrin 3 | 0.0174962 |
| H1-4 | H1.4 linker histone, cluster member | 0.0174621 |
| PDS5B | PDS5 cohesin associated factor B | 0.0173685 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0172386 |
| RHOH | ras homolog family member H | 0.0172199 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0166896 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0163023 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0160334 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0154751 |
| THBS1 | thrombospondin 1 | 0.0151563 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0150565 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0149514 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0146475 |
| WDR43 | WD repeat domain 43 | 0.0145664 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.014528 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0143493 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0143243 |
| EMP1 | epithelial membrane protein 1 | 0.0142917 |
| CCNA2 | cyclin A2 | 0.0142155 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0141933 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0140372 |
| PTK2 | protein tyrosine kinase 2 | 0.0139038 |
| ECT2 | epithelial cell transforming 2 | 0.013886 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0138192 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0135968 |
| MKI67 | marker of proliferation Ki-67 | 0.0135377 |
| RBM33 | RNA binding motif protein 33 | 0.0134804 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0134788 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.013355 |
| MYO6 | myosin VI | 0.0133085 |
| ANLN | anillin, actin binding protein | 0.0132959 |
| CDC14A | cell division cycle 14A | 0.0132066 |
| SERINC1 | serine incorporator 1 | 0.0131731 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0130756 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0130558 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0128581 |
| CORO1C | coronin, actin binding protein, 1C | 0.0127832 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0127369 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0127368 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0126454 |
| TMEM39A | transmembrane protein 39A | 0.0125259 |
| MB21D2 | Mab-21 domain containing 2 | 0.0125168 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0124923 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0123805 |
| PCDH17 | protocadherin 17 | 0.0123465 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0122095 |
| ZNF217 | zinc finger protein 217 | 0.0121978 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0121694 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0121236 |
| H1-0 | H1.0 linker histone | 0.0119389 |
| RAB14 | RAB14, member RAS oncogene family | 0.011923 |
| FMR1 | fragile X mental retardation 1 | 0.0118573 |
| IPO7 | importin 7 | 0.0118309 |
| PDAP1 | PDGFA associated protein 1 | 0.0117554 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0117205 |
| NUAK2 | NUAK family, SNF1-like kinase, 2 | 0.0115701 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0115485 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0115297 |
| OTUD6B | OTU domain containing 6B | 0.0113912 |
| CEP44 | centrosomal protein 44kDa | 0.0113205 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0112752 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0112173 |
| NPTN | neuroplastin | 0.0112052 |
| CDK17 | cyclin-dependent kinase 17 | 0.0111713 |
| MED12 | mediator complex subunit 12 | 0.0111628 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0111555 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0109127 |
| FILIP1 | filamin A interacting protein 1 | 0.0109062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.207716 |
| CADM2 | cell adhesion molecule 2 | -0.172431 |
| VIM | vimentin | -0.16256 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.162279 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.149228 |
| TMSB10 | thymosin beta 10 | -0.139439 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0888555 |
| RPS16 | ribosomal protein S16 | -0.0863815 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0838542 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0801028 |
| RPS6 | ribosomal protein S6 | -0.077961 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0754203 |
| RPS8 | ribosomal protein S8 | -0.0719672 |
| TENM3 | teneurin transmembrane protein 3 | -0.0701927 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0700359 |
| ITGAV | integrin, alpha V | -0.0692923 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0681092 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.066281 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0633763 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0587325 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0575014 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0574335 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0556998 |
| RPL35A | ribosomal protein L35a | -0.0547607 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0532677 |
| RPLP1 | ribosomal protein, large, P1 | -0.0529457 |
| COL1A2 | collagen, type I, alpha 2 | -0.0527541 |
| MEIS2 | Meis homeobox 2 | -0.0496661 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0493899 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0492368 |
| RPL11 | ribosomal protein L11 | -0.0492042 |
| PTMA | prothymosin, alpha | -0.0485336 |
| RPL23 | ribosomal protein L23 | -0.0484262 |
| LRRC4C | leucine rich repeat containing 4C | -0.0482179 |
| SNX6 | sorting nexin 6 | -0.0479209 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0465923 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0459454 |
| SMYD3 | SET and MYND domain containing 3 | -0.0458605 |
| ENO1 | enolase 1, (alpha) | -0.0457261 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0450193 |
| COL5A2 | collagen, type V, alpha 2 | -0.0442995 |
| PCDH9 | protocadherin 9 | -0.0437807 |
| NEBL | nebulette | -0.0417685 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.040178 |
| PFN1 | profilin 1 | -0.039951 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0396891 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039248 |
| GPC3 | glypican 3 | -0.0390476 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0381723 |
| FOXP2 | forkhead box P2 | -0.0380674 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0377098 |
| RPL12 | ribosomal protein L12 | -0.0376743 |
| DST | dystonin | -0.0376228 |
| RAD51B | RAD51 paralog B | -0.0373758 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0371021 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0370942 |
| RPL31 | ribosomal protein L31 | -0.0369994 |
| RPS3 | ribosomal protein S3 | -0.0365279 |
| RPLP2 | ribosomal protein, large, P2 | -0.0364804 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0360994 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0358354 |
| TPR | translocated promoter region, nuclear basket protein | -0.035757 |
| RPS19 | ribosomal protein S19 | -0.0351351 |
| RPS12 | ribosomal protein S12 | -0.0348947 |
| PHIP | pleckstrin homology domain interacting protein | -0.0347726 |
| CUX1 | cut-like homeobox 1 | -0.0346355 |
| ACTG1 | actin gamma 1 | -0.0345476 |
| COL3A1 | collagen, type III, alpha 1 | -0.0342719 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0342598 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0339826 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.03368 |
| RPL36A | ribosomal protein L36a | -0.0335937 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0335406 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0335122 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.033501 |
| RPL37 | ribosomal protein L37 | -0.0334681 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0331027 |
| PRTG | protogenin | -0.0329948 |
| PCDH7 | protocadherin 7 | -0.0328795 |
| HMCN1 | hemicentin 1 | -0.0327734 |
| FBXO17 | F-box protein 17 | -0.0327524 |
| ANK2 | ankyrin 2, neuronal | -0.0327112 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0326183 |
| BPTF | bromodomain PHD finger transcription factor | -0.0322945 |
| TOX | thymocyte selection-associated high mobility group box | -0.0319932 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0317586 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0316326 |
| PRELID2 | PRELI domain containing 2 | -0.0315334 |
| RPS13 | ribosomal protein S13 | -0.03153 |
| MAP4 | microtubule-associated protein 4 | -0.03138 |
| RPL37A | ribosomal protein L37a | -0.0309112 |
| SRP54 | signal recognition particle 54kDa | -0.0305302 |
| NTM | neurotrimin | -0.0299985 |
| FTL | ferritin, light polypeptide | -0.0298875 |
| RPL5 | ribosomal protein L5 | -0.0298603 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0296658 |
| GNAS | GNAS complex locus | -0.0295014 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0292526 |
| RPS21 | ribosomal protein S21 | -0.0292516 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0291692 |
