| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bexarotene perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bexarotene_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.13574 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.134994 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.097874 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0878249 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0734344 |
| ITGA1 | integrin, alpha 1 | 0.0730728 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0669496 |
| OGA | O-GlcNAcase | 0.0640248 |
| AHR | aryl hydrocarbon receptor | 0.0634146 |
| GOLGA4 | golgin A4 | 0.0585462 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.058229 |
| CD109 | CD109 molecule | 0.0578556 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0570962 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0559682 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0556356 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0545282 |
| RNF145 | ring finger protein 145 | 0.0542323 |
| HELZ | helicase with zinc finger | 0.0540155 |
| TPR | translocated promoter region, nuclear basket protein | 0.053511 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.052713 |
| ADD3 | adducin 3 (gamma) | 0.0520017 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0514205 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0505021 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0498468 |
| SMAD3 | SMAD family member 3 | 0.0488204 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0483344 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0480993 |
| OSMR | oncostatin M receptor | 0.0476743 |
| ETNK1 | ethanolamine kinase 1 | 0.0474212 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0473618 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0469296 |
| COPA | coatomer protein complex, subunit alpha | 0.0468882 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0466339 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0465691 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.046191 |
| CENPF | centromere protein F, 350/400kDa | 0.0455925 |
| SMOX | spermine oxidase | 0.0451375 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.044253 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.043262 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0430375 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0429663 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0412326 |
| RUNX2 | runt-related transcription factor 2 | 0.0406575 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0399739 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0395335 |
| NRP1 | neuropilin 1 | 0.0395292 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0387788 |
| AFDN | afadin, adherens junction formation factor | 0.0387236 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0385388 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.038187 |
| ETV6 | ets variant 6 | 0.0378961 |
| NEK7 | NIMA-related kinase 7 | 0.0376008 |
| CDC73 | cell division cycle 73 | 0.0362661 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.035942 |
| ZNF292 | zinc finger protein 292 | 0.0356365 |
| PELO | pelota homolog (Drosophila) | 0.0355793 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.035572 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0352217 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0351798 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0351296 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0348861 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0347999 |
| CD44 | CD44 molecule (Indian blood group) | 0.0344491 |
| CAB39 | calcium binding protein 39 | 0.0343915 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0340465 |
| WDR26 | WD repeat domain 26 | 0.0338942 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0338252 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0329558 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0323463 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0317789 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0316959 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0314302 |
| SMYD3 | SET and MYND domain containing 3 | 0.0313103 |
| DENND4C | DENN/MADD domain containing 4C | 0.031269 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0311983 |
| TMEM156 | transmembrane protein 156 | 0.0311739 |
| FAM13A | family with sequence similarity 13, member A | 0.0310241 |
| DSCAM | Down syndrome cell adhesion molecule | 0.030898 |
| FNBP1 | formin binding protein 1 | 0.0308373 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0307628 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0306008 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0305134 |
| TMEM165 | transmembrane protein 165 | 0.0304262 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.030315 |
| CLTC | clathrin, heavy chain (Hc) | 0.0300899 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0299466 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0295042 |
| MKI67 | marker of proliferation Ki-67 | 0.0293389 |
| DST | dystonin | 0.0292852 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0291993 |
| FAF2 | Fas associated factor family member 2 | 0.0289755 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0286867 |
| JMJD1C | jumonji domain containing 1C | 0.0286746 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0284252 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0282304 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0281239 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0280139 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0279074 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0279011 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0278215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.281787 |
| FN1 | fibronectin 1 | -0.146736 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14437 |
| HMGA2 | high mobility group AT-hook 2 | -0.123971 |
| SQSTM1 | sequestosome 1 | -0.0852168 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0849867 |
| TMSB10 | thymosin beta 10 | -0.0799946 |
| ASPH | aspartate beta-hydroxylase | -0.0683794 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0607511 |
| INTS6 | integrator complex subunit 6 | -0.0607226 |
| HLA-B | major histocompatibility complex, class I, B | -0.0600906 |
| STC2 | stanniocalcin 2 | -0.0574314 |
| LMNA | lamin A/C | -0.0572368 |
| S100A6 | S100 calcium binding protein A6 | -0.0562889 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0545791 |
| PTMA | prothymosin, alpha | -0.0545289 |
| FTL | ferritin, light polypeptide | -0.0535883 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0514541 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0504497 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0483116 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0476216 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0464371 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0450112 |
| NDRG1 | N-myc downstream regulated 1 | -0.0448873 |
| ACTG1 | actin gamma 1 | -0.0439646 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.04063 |
| AEBP2 | AE binding protein 2 | -0.0399339 |
| S100A10 | S100 calcium binding protein A10 | -0.0383307 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0382093 |
| IER3 | immediate early response 3 | -0.0375117 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0375043 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0372756 |
| LRRC23 | leucine rich repeat containing 23 | -0.0367988 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0349645 |
| RPL35A | ribosomal protein L35a | -0.0340156 |
| SYT1 | synaptotagmin I | -0.0339864 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0337071 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0335324 |
| TENM4 | teneurin transmembrane protein 4 | -0.0332664 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0331328 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0324237 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0322105 |
| GNAS | GNAS complex locus | -0.0321383 |
| MCL1 | myeloid cell leukemia 1 | -0.0321105 |
| POTEF | POTE ankyrin domain family, member F | -0.0319992 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0319944 |
| RPLP1 | ribosomal protein, large, P1 | -0.0317141 |
| SFTPA2 | surfactant protein A2 | -0.0314054 |
| B2M | beta-2-microglobulin | -0.031138 |
| RPL26 | ribosomal protein L26 | -0.0308771 |
| PALLD | palladin, cytoskeletal associated protein | -0.0307285 |
| EGR1 | early growth response 1 | -0.0305712 |
| TMSB4X | thymosin beta 4, X-linked | -0.0298022 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0295791 |
| RNF213 | ring finger protein 213 | -0.0289879 |
| RPL31 | ribosomal protein L31 | -0.028622 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0285073 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0283908 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0283164 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0279123 |
| RPL37A | ribosomal protein L37a | -0.0276874 |
| RPS8 | ribosomal protein S8 | -0.0275633 |
| RPL9 | ribosomal protein L9 | -0.0274089 |
| RPS24 | ribosomal protein S24 | -0.0273028 |
| EMP1 | epithelial membrane protein 1 | -0.0272821 |
| IFI44L | interferon-induced protein 44-like | -0.0265906 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0258503 |
| RPL38 | ribosomal protein L38 | -0.0257963 |
| RPS12 | ribosomal protein S12 | -0.0255741 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0254285 |
| HLA-A | major histocompatibility complex, class I, A | -0.0253566 |
| RACK1 | receptor for activated C kinase 1 | -0.0252519 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0252337 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0251034 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0244079 |
| IFRD1 | interferon-related developmental regulator 1 | -0.02408 |
| SFRP1 | secreted frizzled-related protein 1 | -0.024056 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0239839 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0239194 |
| ABR | active BCR-related | -0.023606 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0235899 |
| JUN | jun proto-oncogene | -0.022946 |
| RPL12 | ribosomal protein L12 | -0.0228126 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0227537 |
| RPS29 | ribosomal protein S29 | -0.0225338 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0224402 |
| VCL | vinculin | -0.0223114 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0223106 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0220166 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0218193 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0217087 |
| RPS6 | ribosomal protein S6 | -0.0216633 |
| ENO1 | enolase 1, (alpha) | -0.0216222 |
| CTSD | cathepsin D | -0.021534 |
| MAP1B | microtubule-associated protein 1B | -0.0213846 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0213556 |
| RPL23 | ribosomal protein L23 | -0.0210233 |
| CCDC138 | coiled-coil domain containing 138 | -0.0209042 |
| HMGA1 | high mobility group AT-hook 1 | -0.0207067 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0206174 |
