| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.129798 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0951873 |
| YAP1 | Yes-associated protein 1 | 0.0745667 |
| ASPH | aspartate beta-hydroxylase | 0.0724139 |
| TPM3 | tropomyosin 3 | 0.0680299 |
| AREG | amphiregulin | 0.06447 |
| MMP12 | matrix metallopeptidase 12 | 0.0629687 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.061157 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0572237 |
| HMGA2 | high mobility group AT-hook 2 | 0.0545961 |
| JMJD1C | jumonji domain containing 1C | 0.0528063 |
| DST | dystonin | 0.0527417 |
| MTAP | methylthioadenosine phosphorylase | 0.0484073 |
| RRM2 | ribonucleotide reductase M2 | 0.0472787 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0450024 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0444649 |
| EHBP1 | EH domain binding protein 1 | 0.0438498 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0436715 |
| RPS12 | ribosomal protein S12 | 0.0434601 |
| VCL | vinculin | 0.0418719 |
| MKI67 | marker of proliferation Ki-67 | 0.0415425 |
| RPL37A | ribosomal protein L37a | 0.0376054 |
| NHSL1 | NHS-like 1 | 0.037485 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0373589 |
| NEBL | nebulette | 0.034904 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0347177 |
| RPL3 | ribosomal protein L3 | 0.03431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0338166 |
| NLGN1 | neuroligin 1 | 0.0337551 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0328676 |
| PDGFC | platelet derived growth factor C | 0.0322258 |
| INTS6 | integrator complex subunit 6 | 0.0320211 |
| RAB7A | RAB7A, member RAS oncogene family | 0.031672 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0304715 |
| RAB10 | RAB10, member RAS oncogene family | 0.0300875 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0296294 |
| ANXA1 | annexin A1 | 0.0282765 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0280482 |
| VMP1 | vacuole membrane protein 1 | 0.0275847 |
| MCL1 | myeloid cell leukemia 1 | 0.0275072 |
| EDARADD | EDAR-associated death domain | 0.0269281 |
| RPS6 | ribosomal protein S6 | 0.0269037 |
| TPI1 | triosephosphate isomerase 1 | 0.0267413 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0267191 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.026555 |
| GOLGB1 | golgin B1 | 0.02644 |
| HDGF | hepatoma-derived growth factor | 0.0263243 |
| CENPF | centromere protein F, 350/400kDa | 0.026215 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0252411 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0249167 |
| BRD2 | bromodomain containing 2 | 0.0240629 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0238492 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0237876 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0237337 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0237077 |
| SETD5 | SET domain containing 5 | 0.0235444 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0235307 |
| RTN4 | reticulon 4 | 0.0234055 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0233004 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0232593 |
| FNIP1 | folliculin interacting protein 1 | 0.0231944 |
| ERBIN | erbb2 interacting protein | 0.02312 |
| RCOR1 | REST corepressor 1 | 0.0229572 |
| BCHE | butyrylcholinesterase | 0.0228131 |
| PCM1 | pericentriolar material 1 | 0.022643 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0223979 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0220998 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0219811 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0215007 |
| SNX14 | sorting nexin 14 | 0.0212753 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0211284 |
| DSPP | dentin sialophosphoprotein | 0.0210683 |
| CUX1 | cut-like homeobox 1 | 0.021055 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0207891 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0206904 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0206127 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0204667 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0203233 |
| TENM3 | teneurin transmembrane protein 3 | 0.0202987 |
| RPS23 | ribosomal protein S23 | 0.0202116 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0199045 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.019857 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0197658 |
| PRKCE | protein kinase C, epsilon | 0.0196521 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0195607 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0195147 |
| HDAC9 | histone deacetylase 9 | 0.0193203 |
| RPS8 | ribosomal protein S8 | 0.0192796 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0189504 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0184024 |
| RPS29 | ribosomal protein S29 | 0.0183391 |
| RPS27 | ribosomal protein S27 | 0.018249 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0181318 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0181308 |
| TPM4 | tropomyosin 4 | 0.0181136 |
| AATF | apoptosis antagonizing transcription factor | 0.0181103 |
| EGR1 | early growth response 1 | 0.0178964 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0176319 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0173077 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0173009 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.130571 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0713028 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0653013 |
| TMSB10 | thymosin beta 10 | -0.0640597 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0599747 |
| MYL12B | myosin, light chain 12B, regulatory | -0.059302 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0534287 |
| EDN1 | endothelin 1 | -0.0481115 |
| CCND1 | cyclin D1 | -0.0457093 |
| TMEM123 | transmembrane protein 123 | -0.0455177 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0441107 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0418882 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0405977 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0405344 |
| MGAT4C | MGAT4 family, member C | -0.0401321 |
| RPLP1 | ribosomal protein, large, P1 | -0.0400535 |
| RPS24 | ribosomal protein S24 | -0.03863 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0382169 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0379947 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0374806 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0361118 |
| CLDN1 | claudin 1 | -0.0351503 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0350009 |
| KLF6 | Kruppel-like factor 6 | -0.0349776 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0348747 |
| PCDH7 | protocadherin 7 | -0.0345233 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0341212 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0337191 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0334342 |
| ACTG1 | actin gamma 1 | -0.0331208 |
| NPR2 | natriuretic peptide receptor 2 | -0.0330186 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0329528 |
| MATR3 | matrin 3 | -0.0328005 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0323496 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0315868 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0313901 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0309416 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0308589 |
| ATP11A | ATPase, class VI, type 11A | -0.0303354 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0296132 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0293669 |
| RLF | rearranged L-myc fusion | -0.0292649 |
| ECT2 | epithelial cell transforming 2 | -0.0290929 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0289238 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0289219 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0284684 |
| HMGB1 | high mobility group box 1 | -0.0284221 |
| XPO7 | exportin 7 | -0.0279398 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0269647 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.026323 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0257238 |
| H1-0 | H1.0 linker histone | -0.0255653 |
| SEPTIN7 | septin 7 | -0.025523 |
| FUS | FUS RNA binding protein | -0.0253839 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0252898 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0247012 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0246378 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0246286 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0244969 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0241731 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0239245 |
| GCG | glucagon | -0.0234548 |
| NF1 | neurofibromin 1 | -0.0234268 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.023178 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0230767 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0228609 |
| CAVIN1 | caveolae associated protein 1 | -0.0226928 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0225445 |
| RPL27A | ribosomal protein L27a | -0.0224396 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0217991 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0215657 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0215213 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0214493 |
| CCNI | cyclin I | -0.0214257 |
| TMEM131 | transmembrane protein 131 | -0.0213739 |
| PEG10 | paternally expressed 10 | -0.021331 |
| HMGB2 | high mobility group box 2 | -0.0213111 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0211875 |
| SPAG9 | sperm associated antigen 9 | -0.0211097 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0210582 |
| MED13 | mediator complex subunit 13 | -0.0208866 |
| GNAS | GNAS complex locus | -0.0208383 |
| ARF1 | ADP-ribosylation factor 1 | -0.0207525 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0207284 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0204799 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0204793 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0203974 |
| YBX3 | Y box binding protein 3 | -0.0202909 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0201915 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.020149 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0200333 |
| PTMS | parathymosin | -0.0199954 |
| HMGA1 | high mobility group AT-hook 1 | -0.019923 |
| TUBB | tubulin, beta class I | -0.0197811 |
| SYT1 | synaptotagmin I | -0.0195975 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.0192617 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0191544 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0191104 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0191092 |
| RPL26 | ribosomal protein L26 | -0.019063 |
