| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0888754 |
| NDRG1 | N-myc downstream regulated 1 | 0.0854965 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0716692 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0590326 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.054559 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0441323 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0435831 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0407599 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0375349 |
| AHNAK | AHNAK nucleoprotein | 0.0374176 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0373746 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0357054 |
| ASPH | aspartate beta-hydroxylase | 0.035103 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0323229 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0311233 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0302576 |
| APP | amyloid beta (A4) precursor protein | 0.0286017 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0284658 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0284108 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0265213 |
| TMF1 | TATA element modulatory factor 1 | 0.0263932 |
| COL5A1 | collagen, type V, alpha 1 | 0.0259343 |
| MKI67 | marker of proliferation Ki-67 | 0.0247381 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0246396 |
| DST | dystonin | 0.0246303 |
| CALR | calreticulin | 0.0245942 |
| RRBP1 | ribosome binding protein 1 | 0.0233376 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.022976 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0225821 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0225005 |
| H1-4 | H1.4 linker histone, cluster member | 0.0219471 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0217149 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0216545 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0212693 |
| ARRDC3 | arrestin domain containing 3 | 0.0203627 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0199131 |
| GOLGB1 | golgin B1 | 0.0197977 |
| SFTPA2 | surfactant protein A2 | 0.019792 |
| CENPF | centromere protein F, 350/400kDa | 0.0189598 |
| H1-0 | H1.0 linker histone | 0.018901 |
| RPS2 | ribosomal protein S2 | 0.0186399 |
| RPL3 | ribosomal protein L3 | 0.0184834 |
| ATF4 | activating transcription factor 4 | 0.0179643 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.017768 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0177629 |
| SDC2 | syndecan 2 | 0.0176633 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0172353 |
| SDC4 | syndecan 4 | 0.0168524 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0166245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.016491 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0162842 |
| GOLT1B | golgi transport 1B | 0.0159894 |
| CLU | clusterin | 0.0158339 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0157964 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0154903 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0151937 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0149691 |
| RPL14 | ribosomal protein L14 | 0.0149043 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0147881 |
| SERINC1 | serine incorporator 1 | 0.0147168 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0146774 |
| PMM2 | phosphomannomutase 2 | 0.0146486 |
| FAM219A | family with sequence similarity 219, member A | 0.0146397 |
| CAVIN1 | caveolae associated protein 1 | 0.0138505 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0138097 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0137272 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.013716 |
| CENPE | centromere protein E, 312kDa | 0.0137094 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0135396 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0135053 |
| GPR173 | G protein-coupled receptor 173 | 0.0132808 |
| COL3A1 | collagen, type III, alpha 1 | 0.0132683 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0132173 |
| OSBP | oxysterol binding protein | 0.0129467 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0129402 |
| SAFB | scaffold attachment factor B | 0.0128811 |
| LAMC2 | laminin, gamma 2 | 0.0126482 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0125424 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0122911 |
| MLF1 | myeloid leukemia factor 1 | 0.0122769 |
| RBM15 | RNA binding motif protein 15 | 0.0122387 |
| GOLGA2 | golgin A2 | 0.0122131 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0122082 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.0120143 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0119083 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.0119031 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0118143 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0118054 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.011778 |
| RPL13A | ribosomal protein L13a | 0.0117719 |
| RPS6 | ribosomal protein S6 | 0.0117257 |
| TPX2 | TPX2, microtubule-associated | 0.0116995 |
| EMP1 | epithelial membrane protein 1 | 0.0116648 |
| TPM3 | tropomyosin 3 | 0.0116529 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0116167 |
| ZNF160 | zinc finger protein 160 | 0.0113374 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0109268 |
| RPS7 | ribosomal protein S7 | 0.0108943 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0108884 |
| ODF2 | outer dense fiber of sperm tails 2 | 0.0108451 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.341408 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.293296 |
| VIM | vimentin | -0.217698 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.130063 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125997 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.122454 |
| CD44 | CD44 molecule (Indian blood group) | -0.116971 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0909945 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0795391 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0733325 |
| MT2A | metallothionein 2A | -0.0705647 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0645356 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0640642 |
| CADM1 | cell adhesion molecule 1 | -0.0616301 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0610802 |
| COL1A1 | collagen, type I, alpha 1 | -0.0588723 |
| ACTG1 | actin gamma 1 | -0.0578924 |
| TPM4 | tropomyosin 4 | -0.0571003 |
| RPL35A | ribosomal protein L35a | -0.0557598 |
| COL1A2 | collagen, type I, alpha 2 | -0.0550405 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0524358 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0508444 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0499828 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0498893 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0498168 |
| MAP1B | microtubule-associated protein 1B | -0.0489569 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0479586 |
| POTEF | POTE ankyrin domain family, member F | -0.0462429 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0460577 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0457222 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.04475 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0441322 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0417093 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0415405 |
| RPLP0 | ribosomal protein, large, P0 | -0.0393717 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.039087 |
| PTK2 | protein tyrosine kinase 2 | -0.0388435 |
| TRAM1 | translocation associated membrane protein 1 | -0.0376017 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0374083 |
| TAPBP | TAP binding protein (tapasin) | -0.0373379 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0370504 |
| HMGA1 | high mobility group AT-hook 1 | -0.0370436 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0368095 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0366592 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0360666 |
| VCAN | versican | -0.0353871 |
| HMGA2 | high mobility group AT-hook 2 | -0.0351916 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0348083 |
| IL6ST | interleukin 6 signal transducer | -0.0342925 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0341112 |
| IL6 | interleukin 6 | -0.0340823 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0337979 |
| AXL | AXL receptor tyrosine kinase | -0.0337083 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0336374 |
| FLNA | filamin A, alpha | -0.0334055 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0331573 |
| NRP1 | neuropilin 1 | -0.0330207 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0329506 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0328494 |
| RPL23 | ribosomal protein L23 | -0.0322862 |
| CDH13 | cadherin 13 | -0.0321458 |
| WASF2 | WAS protein family, member 2 | -0.0321007 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0316902 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0312455 |
| EGFR | epidermal growth factor receptor | -0.0308771 |
| FTL | ferritin, light polypeptide | -0.0308283 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0306787 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0306302 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0305584 |
| SEPTIN7 | septin 7 | -0.0305352 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0304434 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0298203 |
| SMAD3 | SMAD family member 3 | -0.0297663 |
| ATP13A3 | ATPase type 13A3 | -0.0290674 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0288919 |
| DSTN | destrin (actin depolymerizing factor) | -0.0288787 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0288601 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0288596 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0288178 |
| ENO1 | enolase 1, (alpha) | -0.0285346 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0280733 |
| LOX | lysyl oxidase | -0.0278992 |
| SPAG9 | sperm associated antigen 9 | -0.0277873 |
| IER3 | immediate early response 3 | -0.0277811 |
| PERP | PERP, TP53 apoptosis effector | -0.0276542 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0271916 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0270426 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0270165 |
| HLA-B | major histocompatibility complex, class I, B | -0.0269305 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0268493 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0267684 |
| CCND1 | cyclin D1 | -0.026722 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0266639 |
| PFN1 | profilin 1 | -0.0266296 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0264953 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0263614 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0258985 |
| TMSB10 | thymosin beta 10 | -0.0258118 |
| FOSL1 | FOS-like antigen 1 | -0.0257757 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0257464 |
