| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0792143 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0670839 |
| DSPP | dentin sialophosphoprotein | 0.0583036 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0572466 |
| AHNAK | AHNAK nucleoprotein | 0.0563312 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0554736 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0516976 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0495718 |
| VCL | vinculin | 0.0488008 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0421648 |
| ASPH | aspartate beta-hydroxylase | 0.0418223 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0411214 |
| KRT18 | keratin 18, type I | 0.040514 |
| CENPF | centromere protein F, 350/400kDa | 0.0370457 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0364641 |
| RPS6 | ribosomal protein S6 | 0.0363221 |
| RPS2 | ribosomal protein S2 | 0.0354602 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.031556 |
| RPL3 | ribosomal protein L3 | 0.0311691 |
| VEGFA | vascular endothelial growth factor A | 0.0311549 |
| TPM3 | tropomyosin 3 | 0.0294846 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0293139 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0284391 |
| ITGA6 | integrin, alpha 6 | 0.0282297 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0275928 |
| TXNIP | thioredoxin interacting protein | 0.0274251 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0270389 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268908 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0264879 |
| PKP2 | plakophilin 2 | 0.0264263 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0263594 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0260438 |
| YBX1 | Y box binding protein 1 | 0.0256899 |
| DSG2 | desmoglein 2 | 0.0251799 |
| PRSS3 | protease, serine, 3 | 0.0236757 |
| H1-4 | H1.4 linker histone, cluster member | 0.0232641 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0224573 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0208762 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0208028 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.020067 |
| EHF | ets homologous factor | 0.0198816 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0197658 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0194609 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0189679 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0186011 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0185516 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0184259 |
| LAMC2 | laminin, gamma 2 | 0.017946 |
| NOSTRIN | nitric oxide synthase trafficking | 0.0170901 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0165263 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.016425 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.016383 |
| RAB10 | RAB10, member RAS oncogene family | 0.0162381 |
| PDZD8 | PDZ domain containing 8 | 0.0159878 |
| RNF43 | ring finger protein 43 | 0.0159301 |
| TSC22D1 | TSC22 domain family, member 1 | 0.015725 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0155801 |
| RRM2 | ribonucleotide reductase M2 | 0.015442 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0153682 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0146481 |
| FAM13A | family with sequence similarity 13, member A | 0.0146048 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0145631 |
| MYO5B | myosin VB | 0.014398 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0142445 |
| GOLGB1 | golgin B1 | 0.014168 |
| RPS7 | ribosomal protein S7 | 0.0141587 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0141313 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0141109 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0137878 |
| HMGB2 | high mobility group box 2 | 0.0135264 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0133188 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0131048 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0130209 |
| DST | dystonin | 0.0127606 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0126021 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.012521 |
| GOLM1 | golgi membrane protein 1 | 0.0124673 |
| MKI67 | marker of proliferation Ki-67 | 0.0123651 |
| CTBP2 | C-terminal binding protein 2 | 0.0123596 |
| TRIM2 | tripartite motif containing 2 | 0.0122172 |
| EPCAM | epithelial cell adhesion molecule | 0.0121823 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0120275 |
| GPSM2 | G-protein signaling modulator 2 | 0.0119329 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0119083 |
| H1-0 | H1.0 linker histone | 0.0118664 |
| TMEM45B | transmembrane protein 45B | 0.0117797 |
| ANLN | anillin, actin binding protein | 0.0117083 |
| PRELID2 | PRELI domain containing 2 | 0.0116902 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0116087 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0116037 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0115852 |
| PLS1 | plastin 1 | 0.0114591 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0113667 |
| TMSB4X | thymosin beta 4, X-linked | 0.0113644 |
| ATP10B | ATPase, class V, type 10B | 0.0111308 |
| ABHD17C | abhydrolase domain containing 17C | 0.011106 |
| TPX2 | TPX2, microtubule-associated | 0.0109232 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0108972 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0108775 |
| SFTPA2 | surfactant protein A2 | 0.0108105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.19947 |
| TMSB10 | thymosin beta 10 | -0.142909 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.124462 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0924195 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0727675 |
| HMGA1 | high mobility group AT-hook 1 | -0.057542 |
| MUC17 | mucin 17, cell surface associated | -0.0548288 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0545406 |
| RPL35A | ribosomal protein L35a | -0.0521713 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0513828 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0508039 |
| LOC112694756 | uncharaterized LOC112694756 | -0.050747 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0467282 |
| RPLP1 | ribosomal protein, large, P1 | -0.0463443 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0439322 |
| ACTN4 | actinin, alpha 4 | -0.0433131 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0419057 |
| RPS24 | ribosomal protein S24 | -0.0412427 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0391513 |
| CALB1 | calbindin 1, 28kDa | -0.0389516 |
| ACTG1 | actin gamma 1 | -0.0386938 |
| FTL | ferritin, light polypeptide | -0.0384095 |
| LMNA | lamin A/C | -0.038026 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0376488 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0362317 |
| PIGR | polymeric immunoglobulin receptor | -0.0360731 |
| ITGB4 | integrin, beta 4 | -0.035583 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0347306 |
| VDAC1 | voltage-dependent anion channel 1 | -0.034675 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0346666 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0346655 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0342642 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0340887 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0339696 |
| PTEN | phosphatase and tensin homolog | -0.0339003 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0336594 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0334668 |
| GDF15 | growth differentiation factor 15 | -0.0330764 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0329428 |
| S100P | S100 calcium binding protein P | -0.0328385 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0319579 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0316797 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0312798 |
| S100A6 | S100 calcium binding protein A6 | -0.0311213 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0310928 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.030834 |
| FAT1 | FAT atypical cadherin 1 | -0.0305989 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0305498 |
| RPL23 | ribosomal protein L23 | -0.0302973 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0302019 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0296358 |
| NFIA | nuclear factor I/A | -0.0294518 |
| PARD3 | par-3 family cell polarity regulator | -0.0294027 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0291474 |
| PERP | PERP, TP53 apoptosis effector | -0.0290867 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0290266 |
| RPS25 | ribosomal protein S25 | -0.028624 |
| RPLP2 | ribosomal protein, large, P2 | -0.0281008 |
| RPS19 | ribosomal protein S19 | -0.0279723 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.027791 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0275644 |
| CCNI | cyclin I | -0.0274935 |
| RPL27A | ribosomal protein L27a | -0.0273885 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.02737 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0273544 |
| COG5 | component of oligomeric golgi complex 5 | -0.0270856 |
| RPL5 | ribosomal protein L5 | -0.0270843 |
| LDHA | lactate dehydrogenase A | -0.0269104 |
| GOLGA4 | golgin A4 | -0.0268479 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0267297 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0264464 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.025489 |
| RPS11 | ribosomal protein S11 | -0.0253833 |
| POTEF | POTE ankyrin domain family, member F | -0.0253811 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0252285 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0250727 |
| PTK2 | protein tyrosine kinase 2 | -0.0249823 |
| PKM | pyruvate kinase, muscle | -0.0249237 |
| NF1 | neurofibromin 1 | -0.0248285 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0247346 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0247148 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0244046 |
| AGR2 | anterior gradient 2 | -0.0240146 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0236694 |
| WDR45B | WD repeat domain 45B | -0.0236621 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.02364 |
| RPL31 | ribosomal protein L31 | -0.0233301 |
| USP34 | ubiquitin specific peptidase 34 | -0.0232205 |
| RPS23 | ribosomal protein S23 | -0.0232109 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0227102 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0224811 |
| RPS21 | ribosomal protein S21 | -0.0224031 |
| S100A14 | S100 calcium binding protein A14 | -0.0223759 |
| RPL28 | ribosomal protein L28 | -0.0222006 |
| GPHN | gephyrin | -0.0221589 |
| MED13 | mediator complex subunit 13 | -0.022125 |
| MSI2 | musashi RNA-binding protein 2 | -0.0218192 |
| JUP | junction plakoglobin | -0.0217168 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0216289 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0216138 |
