| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bicalutamide_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.119379 |
| MT2A | metallothionein 2A | 0.10857 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0840806 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0681008 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0623574 |
| VCL | vinculin | 0.0550306 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0547899 |
| CAPRIN2 | caprin family member 2 | 0.0502248 |
| EMP1 | epithelial membrane protein 1 | 0.0499747 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0479339 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0456038 |
| EZR | ezrin | 0.0454328 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0422678 |
| CENPF | centromere protein F, 350/400kDa | 0.0407967 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0399253 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0394169 |
| MT1E | metallothionein 1E | 0.0374177 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370188 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0366889 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0355638 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.035444 |
| MKI67 | marker of proliferation Ki-67 | 0.0351243 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0343908 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0331459 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0330803 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0329212 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0328465 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0328416 |
| ANGPTL4 | angiopoietin-like 4 | 0.0328292 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0326085 |
| DST | dystonin | 0.0319644 |
| UBC | ubiquitin C | 0.0318262 |
| AHNAK | AHNAK nucleoprotein | 0.0309677 |
| ARRDC3 | arrestin domain containing 3 | 0.0306981 |
| PHF21A | PHD finger protein 21A | 0.0278818 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0278244 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0270832 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0261884 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0260844 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0257053 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0249369 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0244909 |
| ASPH | aspartate beta-hydroxylase | 0.0244887 |
| RGS4 | regulator of G-protein signaling 4 | 0.0243985 |
| RTTN | rotatin | 0.0242915 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0241678 |
| TXNRD1 | thioredoxin reductase 1 | 0.0239909 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0234156 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0233148 |
| F2R | coagulation factor II (thrombin) receptor | 0.0231243 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0229309 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0227846 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0226099 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.022576 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0224647 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0223573 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0222455 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0222159 |
| ANO6 | anoctamin 6 | 0.0220623 |
| MT1X | metallothionein 1X | 0.0220124 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0220014 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0219475 |
| ERBIN | erbb2 interacting protein | 0.0213868 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0211016 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0210545 |
| ARFGEF3 | ARFGEF family member 3 | 0.0202879 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0200752 |
| FNIP1 | folliculin interacting protein 1 | 0.0200198 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0198974 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0196804 |
| YBX3 | Y box binding protein 3 | 0.0195927 |
| USP12 | ubiquitin specific peptidase 12 | 0.0192963 |
| CUL4B | cullin 4B | 0.019068 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0190643 |
| RPL12 | ribosomal protein L12 | 0.0189565 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0184911 |
| SFTPA2 | surfactant protein A2 | 0.0183674 |
| HPCAL1 | hippocalcin-like 1 | 0.0180696 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0180002 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0179078 |
| AREG | amphiregulin | 0.0178871 |
| GOLGB1 | golgin B1 | 0.0177187 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0176048 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0175258 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0172407 |
| MCL1 | myeloid cell leukemia 1 | 0.0172294 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0171344 |
| UTRN | utrophin | 0.0169365 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0168904 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0167914 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.016332 |
| RTN4 | reticulon 4 | 0.0161295 |
| IL6ST | interleukin 6 signal transducer | 0.0159486 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0158069 |
| PLAU | plasminogen activator, urokinase | 0.0157734 |
| SNX14 | sorting nexin 14 | 0.0154918 |
| TRIM38 | tripartite motif containing 38 | 0.0151977 |
| NIN | ninein (GSK3B interacting protein) | 0.0151279 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 | 0.0149448 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0147966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.15019 |
| PTMA | prothymosin, alpha | -0.140602 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121676 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.116512 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.114807 |
| TP63 | tumor protein p63 | -0.107825 |
| CADM2 | cell adhesion molecule 2 | -0.100047 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0928797 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0917591 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0804689 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0756643 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0741639 |
| TMSB10 | thymosin beta 10 | -0.0715336 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0714761 |
| TNS3 | tensin 3 | -0.0690207 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0642281 |
| EPHA4 | EPH receptor A4 | -0.0624321 |
| EFNA5 | ephrin-A5 | -0.0593661 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0577716 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.055609 |
| CD44 | CD44 molecule (Indian blood group) | -0.0528837 |
| TMEM123 | transmembrane protein 123 | -0.052658 |
| VIM | vimentin | -0.0502035 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0497845 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0478503 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0478277 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0476714 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0476284 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0466086 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0427961 |
| DPYD | dihydropyrimidine dehydrogenase | -0.041179 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0395463 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0387222 |
| POTEF | POTE ankyrin domain family, member F | -0.0382877 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0376949 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0370499 |
| PDE10A | phosphodiesterase 10A | -0.0366864 |
| CANX | calnexin | -0.0365986 |
| TMSB4X | thymosin beta 4, X-linked | -0.0364787 |
| HMGA1 | high mobility group AT-hook 1 | -0.0363119 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0356585 |
| DNER | delta/notch-like EGF repeat containing | -0.0355509 |
| ACTG1 | actin gamma 1 | -0.0352037 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0345373 |
| COL5A2 | collagen, type V, alpha 2 | -0.0343712 |
| UBE3C | ubiquitin protein ligase E3C | -0.033939 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0337805 |
| WASF2 | WAS protein family, member 2 | -0.0333639 |
| HDAC9 | histone deacetylase 9 | -0.0329782 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0322262 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0321905 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0321444 |
| CALR | calreticulin | -0.0318744 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0318074 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0316313 |
| RNF213 | ring finger protein 213 | -0.0315996 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0315703 |
| TFRC | transferrin receptor | -0.0313833 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0311238 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0308359 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0304745 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0304045 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0303467 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0300696 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0300327 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0298855 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0298142 |
| DPH6 | diphthamine biosynthesis 6 | -0.0297431 |
| FOXK1 | forkhead box K1 | -0.0292701 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0292434 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0289981 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0289734 |
| DENND1A | DENN/MADD domain containing 1A | -0.0289474 |
| TSC22D1 | TSC22 domain family, member 1 | -0.028888 |
| CMIP | c-Maf inducing protein | -0.0288447 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0286258 |
| ANXA1 | annexin A1 | -0.0284083 |
| PGK1 | phosphoglycerate kinase 1 | -0.0283964 |
| RBM25 | RNA binding motif protein 25 | -0.0280995 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0280392 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0279804 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0278153 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0274835 |
| MAP4 | microtubule-associated protein 4 | -0.0267057 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0265194 |
| RLF | rearranged L-myc fusion | -0.026105 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0260351 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.025963 |
| FTL | ferritin, light polypeptide | -0.0257662 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0257233 |
| NUP58 | nucleoporin 58 | -0.0256873 |
| NPR2 | natriuretic peptide receptor 2 | -0.0255439 |
| EHBP1 | EH domain binding protein 1 | -0.0253435 |
| FUS | FUS RNA binding protein | -0.025196 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0247536 |
| RBM39 | RNA binding motif protein 39 | -0.0247119 |
| WDR45B | WD repeat domain 45B | -0.0244034 |
| HLA-B | major histocompatibility complex, class I, B | -0.0243778 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | -0.0241777 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.024144 |
