| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bicalutamide_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.048087 |
| ARRDC3 | arrestin domain containing 3 | 0.0275645 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0227679 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0216254 |
| RNF145 | ring finger protein 145 | 0.0198982 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.019313 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0161892 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0161612 |
| NGLY1 | N-glycanase 1 | 0.0158187 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0149779 |
| CES1 | carboxylesterase 1 | 0.014477 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0142787 |
| HELZ | helicase with zinc finger | 0.0141273 |
| HYOU1 | hypoxia up-regulated 1 | 0.0134697 |
| ANO6 | anoctamin 6 | 0.0123435 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0119896 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0119614 |
| CCNL1 | cyclin L1 | 0.0119545 |
| MYO1B | myosin IB | 0.0119475 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0118745 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0118021 |
| TPD52 | tumor protein D52 | 0.0116962 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0116904 |
| SLMAP | sarcolemma associated protein | 0.0115812 |
| TPM3 | tropomyosin 3 | 0.0115678 |
| MSN | moesin | 0.0112902 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0111318 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0109514 |
| TMEM165 | transmembrane protein 165 | 0.0106313 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0105504 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0105019 |
| SRP54 | signal recognition particle 54kDa | 0.0102984 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.010141 |
| VEGFA | vascular endothelial growth factor A | 0.0100594 |
| PDE8A | phosphodiesterase 8A | 0.0100036 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0099316 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0098327 |
| PTEN | phosphatase and tensin homolog | 0.00982141 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.00953544 |
| ZNF292 | zinc finger protein 292 | 0.00922882 |
| SETD5 | SET domain containing 5 | 0.00899357 |
| NCKAP1 | NCK-associated protein 1 | 0.00894267 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.008845 |
| TMF1 | TATA element modulatory factor 1 | 0.00880298 |
| RPL3 | ribosomal protein L3 | 0.00849874 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00847825 |
| JMJD1C | jumonji domain containing 1C | 0.00823686 |
| KCMF1 | potassium channel modulatory factor 1 | 0.00813445 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.00808265 |
| RUNX1 | runt-related transcription factor 1 | 0.00805394 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.00799496 |
| VMP1 | vacuole membrane protein 1 | 0.00798667 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00797495 |
| OGA | O-GlcNAcase | 0.00794949 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00786559 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0078222 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0077855 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.00775163 |
| VEGFC | vascular endothelial growth factor C | 0.00752608 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00752067 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.00746395 |
| DTNA | dystrobrevin, alpha | 0.00739475 |
| SEC24A | SEC24 family member A | 0.00734008 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.00731448 |
| TFG | TRK-fused gene | 0.00729625 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.00725718 |
| NUP58 | nucleoporin 58 | 0.00724927 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00724588 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.00721673 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00720494 |
| NPTN | neuroplastin | 0.00713494 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.00704083 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0068545 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00685066 |
| RNF24 | ring finger protein 24 | 0.00682677 |
| ATG14 | autophagy related 14 | 0.00682469 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00676231 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.00673374 |
| QKI | QKI, KH domain containing, RNA binding | 0.00668719 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00658416 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.00657165 |
| INSIG2 | insulin induced gene 2 | 0.00657053 |
| NAPB | N-ethylmaleimide-sensitive factor attachment protein, beta | 0.00654265 |
| SUCO | SUN domain containing ossification factor | 0.00641833 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0063739 |
| YAP1 | Yes-associated protein 1 | 0.00635144 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00634899 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00631812 |
| SLC35F5 | solute carrier family 35, member F5 | 0.00624509 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00611502 |
| CASC3 | cancer susceptibility candidate 3 | 0.00610084 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.00602565 |
| FBRS | fibrosin | 0.00602314 |
| ANXA5 | annexin A5 | 0.00594615 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.00592917 |
| FNIP1 | folliculin interacting protein 1 | 0.00589202 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00586318 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00579328 |
| PHF21A | PHD finger protein 21A | 0.00572236 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00570586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.372654 |
| TMSB10 | thymosin beta 10 | -0.132007 |
| MT2A | metallothionein 2A | -0.1197 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.114513 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.10121 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0962892 |
| ASPH | aspartate beta-hydroxylase | -0.0943992 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0942845 |
| ACTG1 | actin gamma 1 | -0.0898795 |
| TXNRD1 | thioredoxin reductase 1 | -0.0879424 |
| EGFR | epidermal growth factor receptor | -0.0761956 |
| LDHA | lactate dehydrogenase A | -0.0747903 |
| S100A10 | S100 calcium binding protein A10 | -0.0747745 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0714724 |
| LMO7 | LIM domain 7 | -0.0698056 |
| LAMC2 | laminin, gamma 2 | -0.069579 |
| EGR1 | early growth response 1 | -0.064009 |
| RPL35A | ribosomal protein L35a | -0.0636908 |
| ENO1 | enolase 1, (alpha) | -0.0634644 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0607834 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0591376 |
| RPS24 | ribosomal protein S24 | -0.0575038 |
| SEC61G | Sec61 gamma subunit | -0.0560274 |
| RPLP1 | ribosomal protein, large, P1 | -0.0552461 |
| FTL | ferritin, light polypeptide | -0.052338 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0509955 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0495701 |
| ANXA2 | annexin A2 | -0.0489391 |
| RPS3 | ribosomal protein S3 | -0.0469059 |
| STC1 | stanniocalcin 1 | -0.0467424 |
| LAMB3 | laminin, beta 3 | -0.0461386 |
| KRT18 | keratin 18, type I | -0.0443213 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0436124 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0421839 |
| PGK1 | phosphoglycerate kinase 1 | -0.0412027 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0411481 |
| OSMR | oncostatin M receptor | -0.0411005 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0405083 |
| PKM | pyruvate kinase, muscle | -0.039671 |
| PTMA | prothymosin, alpha | -0.0396656 |
| KRT7 | keratin 7, type II | -0.0387045 |
| RPS25 | ribosomal protein S25 | -0.0381569 |
| AREG | amphiregulin | -0.0381222 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0378624 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0376814 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0375702 |
| TES | testin LIM domain protein | -0.0374011 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.03736 |
| RPL34 | ribosomal protein L34 | -0.0367659 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0366359 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0365983 |
| CCND1 | cyclin D1 | -0.0361107 |
| LAMA4 | laminin, alpha 4 | -0.0356914 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0353538 |
| RPLP0 | ribosomal protein, large, P0 | -0.0349271 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0338464 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0338246 |
| RPS8 | ribosomal protein S8 | -0.0337104 |
| RPL37A | ribosomal protein L37a | -0.0336892 |
| HLA-B | major histocompatibility complex, class I, B | -0.0335934 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0335208 |
| IER3 | immediate early response 3 | -0.0330867 |
| CST3 | cystatin C | -0.0321316 |
| KRT8 | keratin 8, type II | -0.030976 |
| VCL | vinculin | -0.030571 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0305166 |
| H1-0 | H1.0 linker histone | -0.0302166 |
| B2M | beta-2-microglobulin | -0.0301752 |
| RPL11 | ribosomal protein L11 | -0.0300506 |
| RPL30 | ribosomal protein L30 | -0.0298278 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0294221 |
| S100A11 | S100 calcium binding protein A11 | -0.0293588 |
| RPL23 | ribosomal protein L23 | -0.0289193 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0287443 |
| S100A6 | S100 calcium binding protein A6 | -0.0280617 |
| RPL31 | ribosomal protein L31 | -0.0280434 |
| RPS27A | ribosomal protein S27a | -0.0280262 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0275754 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0273425 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0273198 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0268428 |
| RPL12 | ribosomal protein L12 | -0.026687 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0264921 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0263442 |
| MT1X | metallothionein 1X | -0.0263098 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0253972 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0246734 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0246288 |
| SCEL | sciellin | -0.0245313 |
| PRDX1 | peroxiredoxin 1 | -0.0240806 |
| S100A9 | S100 calcium binding protein A9 | -0.0239436 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0237251 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0236674 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0236508 |
| RPS21 | ribosomal protein S21 | -0.0234787 |
| RPL19 | ribosomal protein L19 | -0.0234728 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0231315 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0229015 |
| RPS23 | ribosomal protein S23 | -0.0228584 |
| TPI1 | triosephosphate isomerase 1 | -0.0227862 |
