| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bicalutamide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.155322 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.119893 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0812157 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0797715 |
| CD44 | CD44 molecule (Indian blood group) | 0.0794228 |
| RAD51B | RAD51 paralog B | 0.0789341 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0688044 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0667812 |
| OSMR | oncostatin M receptor | 0.0661773 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.06525 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0648518 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0601197 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0594786 |
| NTN4 | netrin 4 | 0.0549606 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0534158 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0528709 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0527186 |
| VMP1 | vacuole membrane protein 1 | 0.05159 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.050068 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0499773 |
| MCL1 | myeloid cell leukemia 1 | 0.0496548 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0493149 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0478841 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0461454 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0456292 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0454634 |
| PRELID2 | PRELI domain containing 2 | 0.0451629 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0449957 |
| MAP1B | microtubule-associated protein 1B | 0.0449089 |
| VCL | vinculin | 0.0448422 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0445701 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0436992 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0432618 |
| ADD3 | adducin 3 (gamma) | 0.0429692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0422889 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0420396 |
| SFTPA2 | surfactant protein A2 | 0.0414753 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0414738 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0407617 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0407554 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0404043 |
| TNNC1 | troponin C type 1 (slow) | 0.040362 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0400143 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0397856 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0396946 |
| EFNA5 | ephrin-A5 | 0.0395696 |
| AOPEP | aminopeptidase O (putative) | 0.0392559 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0391061 |
| NCOA7 | nuclear receptor coactivator 7 | 0.039074 |
| STK38L | serine/threonine kinase 38 like | 0.0383874 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0381517 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0379463 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0379209 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.037463 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0358694 |
| DST | dystonin | 0.0354995 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0354656 |
| OPTN | optineurin | 0.0353838 |
| FAM13A | family with sequence similarity 13, member A | 0.0352754 |
| VEGFA | vascular endothelial growth factor A | 0.0345046 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0344062 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0342539 |
| BPTF | bromodomain PHD finger transcription factor | 0.0336133 |
| EHBP1 | EH domain binding protein 1 | 0.0334994 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0334058 |
| EZR | ezrin | 0.0332373 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0330978 |
| SYAP1 | synapse associated protein 1 | 0.0330853 |
| ECE1 | endothelin converting enzyme 1 | 0.0330182 |
| RNF24 | ring finger protein 24 | 0.0325727 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0317967 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0316565 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.031621 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0313503 |
| MYOF | myoferlin | 0.0311341 |
| IL1R1 | interleukin 1 receptor, type I | 0.0309852 |
| SMAD3 | SMAD family member 3 | 0.0306447 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0300608 |
| AHNAK | AHNAK nucleoprotein | 0.0294774 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0292143 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0289191 |
| JMJD1C | jumonji domain containing 1C | 0.0287737 |
| ITGAV | integrin, alpha V | 0.0283759 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0282969 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0280223 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0278623 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0277372 |
| FLNB | filamin B, beta | 0.0277073 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0276569 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0276563 |
| LUZP1 | leucine zipper protein 1 | 0.0276141 |
| GOLGB1 | golgin B1 | 0.0275803 |
| OGA | O-GlcNAcase | 0.0273974 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.027375 |
| LAMA4 | laminin, alpha 4 | 0.0271928 |
| TGM2 | transglutaminase 2 | 0.0271507 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0271179 |
| IL6ST | interleukin 6 signal transducer | 0.0270018 |
| PFKP | phosphofructokinase, platelet | 0.0268895 |
| NDRG1 | N-myc downstream regulated 1 | 0.0268191 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.204765 |
| CDH13 | cadherin 13 | -0.133147 |
| NRG1 | neuregulin 1 | -0.119936 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.119601 |
| MTSS1 | metastasis suppressor 1 | -0.102235 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.099093 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0956169 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0921967 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0919366 |
| FN1 | fibronectin 1 | -0.0670932 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0641072 |
| HMGA2 | high mobility group AT-hook 2 | -0.0611649 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0579675 |
| STC1 | stanniocalcin 1 | -0.0573538 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0569222 |
| CDK14 | cyclin-dependent kinase 14 | -0.0537411 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0535718 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.053381 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0532644 |
| DNER | delta/notch-like EGF repeat containing | -0.0510898 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0509423 |
| LOX | lysyl oxidase | -0.0503226 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0489849 |
| PARD3 | par-3 family cell polarity regulator | -0.0483605 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0457804 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0438293 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0433692 |
| MEF2A | myocyte enhancer factor 2A | -0.0433161 |
| DTNA | dystrobrevin, alpha | -0.0425273 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0417505 |
| FBN1 | fibrillin 1 | -0.0406235 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0402769 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0397969 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0385248 |
| NAV3 | neuron navigator 3 | -0.0355122 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0354893 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.035255 |
| USP3 | ubiquitin specific peptidase 3 | -0.0351373 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0343029 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0337418 |
| IL1B | interleukin 1, beta | -0.0334888 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331313 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0316458 |
| FAM20C | family with sequence similarity 20, member C | -0.0315724 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.031522 |
| NHSL1 | NHS-like 1 | -0.0307444 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0305736 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0305587 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0305363 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0304829 |
| DENND1A | DENN/MADD domain containing 1A | -0.0296036 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0292588 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0287005 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0284193 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0275254 |
| INTS6 | integrator complex subunit 6 | -0.027471 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0269911 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0266529 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0263374 |
| GLIS3 | GLIS family zinc finger 3 | -0.0262007 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0260937 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0257903 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0254772 |
| VRK2 | vaccinia related kinase 2 | -0.0252481 |
| PTK2 | protein tyrosine kinase 2 | -0.0247627 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0245943 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0245737 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0245264 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0244902 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0239487 |
| NLK | nemo-like kinase | -0.0236749 |
| ANXA10 | annexin A10 | -0.0236103 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0235906 |
| NUP58 | nucleoporin 58 | -0.02297 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0228544 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0227299 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0225549 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0222868 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0214018 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0214016 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0213599 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0213083 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0213031 |
| TSPAN5 | tetraspanin 5 | -0.0211952 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.0211435 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.020864 |
| QKI | QKI, KH domain containing, RNA binding | -0.0207997 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.020632 |
| HELZ | helicase with zinc finger | -0.0204464 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0202699 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0202237 |
| CP | ceruloplasmin (ferroxidase) | -0.0201563 |
| ABCA13 | ATP-binding cassette, sub-family A (ABC1), member 13 | -0.0201402 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0200982 |
| AADAC | arylacetamide deacetylase | -0.0200533 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.019824 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0197589 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0195195 |
| THBD | thrombomodulin | -0.0192721 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0190899 |
