| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bicalutamide_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.170089 |
| FGB | fibrinogen beta chain | 0.123591 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0929745 |
| TPM3 | tropomyosin 3 | 0.0886031 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0862967 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0783176 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0692839 |
| UBC | ubiquitin C | 0.0669254 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0656081 |
| TXNRD1 | thioredoxin reductase 1 | 0.0622174 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0609298 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0514206 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0497257 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0496165 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0484063 |
| VMP1 | vacuole membrane protein 1 | 0.0483983 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0479268 |
| BRD2 | bromodomain containing 2 | 0.0449735 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0448041 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0445922 |
| NTN4 | netrin 4 | 0.0424693 |
| YBX1 | Y box binding protein 1 | 0.0405036 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.040208 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0400852 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.039015 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0388979 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0380728 |
| MCL1 | myeloid cell leukemia 1 | 0.0379941 |
| PLS3 | plastin 3 | 0.0376455 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0369147 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.036646 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0366067 |
| FGG | fibrinogen gamma chain | 0.0364588 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0363461 |
| RPL3 | ribosomal protein L3 | 0.0361617 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0353434 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0349345 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0321884 |
| MKI67 | marker of proliferation Ki-67 | 0.0321861 |
| RPS27A | ribosomal protein S27a | 0.0321088 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0312445 |
| COPA | coatomer protein complex, subunit alpha | 0.0311396 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0311145 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0310805 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0310053 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0308031 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0302909 |
| ERBIN | erbb2 interacting protein | 0.0293618 |
| TPD52 | tumor protein D52 | 0.0293487 |
| KIF5B | kinesin family member 5B | 0.0288598 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0288441 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0284004 |
| FGA | fibrinogen alpha chain | 0.028286 |
| MSN | moesin | 0.0282766 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0274696 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0273422 |
| ASPH | aspartate beta-hydroxylase | 0.0271625 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0264609 |
| SPAG5 | sperm associated antigen 5 | 0.0261491 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0261386 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0260815 |
| SFTPA2 | surfactant protein A2 | 0.0260717 |
| RRM2 | ribonucleotide reductase M2 | 0.0258067 |
| JMJD1C | jumonji domain containing 1C | 0.0255331 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0253466 |
| APP | amyloid beta (A4) precursor protein | 0.0250946 |
| AATF | apoptosis antagonizing transcription factor | 0.0249032 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0245799 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0245257 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0243871 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0242521 |
| HDGF | hepatoma-derived growth factor | 0.0239989 |
| CALU | calumenin | 0.0239118 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0238983 |
| PCBP2 | poly(rC) binding protein 2 | 0.0235116 |
| TPX2 | TPX2, microtubule-associated | 0.023405 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0233004 |
| XPO1 | exportin 1 | 0.0230289 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0228351 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0227609 |
| YTHDC1 | YTH domain containing 1 | 0.0221326 |
| JUN | jun proto-oncogene | 0.0220089 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0217249 |
| PHIP | pleckstrin homology domain interacting protein | 0.0216806 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0211177 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0210803 |
| INO80 | INO80 complex subunit | 0.0210197 |
| ECT2 | epithelial cell transforming 2 | 0.0209817 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0209415 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0206158 |
| GLG1 | golgi glycoprotein 1 | 0.0205235 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.02052 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.020413 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0199187 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0198606 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0198125 |
| TMF1 | TATA element modulatory factor 1 | 0.0196092 |
| CCNY | cyclin Y | 0.0190616 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0190041 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0186486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.246601 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.171716 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.123437 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122382 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.111023 |
| IGF2 | insulin-like growth factor 2 | -0.110129 |
| ACTG1 | actin gamma 1 | -0.106626 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0994898 |
| IER3 | immediate early response 3 | -0.0907045 |
| VIM | vimentin | -0.0796639 |
| TMSB10 | thymosin beta 10 | -0.0738244 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0731649 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0699772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0672647 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0632332 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0618964 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0591731 |
| RPL35A | ribosomal protein L35a | -0.0587976 |
| FNDC3B | fibronectin type III domain containing 3B | -0.055851 |
| RPLP1 | ribosomal protein, large, P1 | -0.0513453 |
| RPS21 | ribosomal protein S21 | -0.0512259 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0495122 |
| PYGL | phosphorylase, glycogen, liver | -0.04859 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0484809 |
| CAVIN1 | caveolae associated protein 1 | -0.0469391 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0451879 |
| S100A10 | S100 calcium binding protein A10 | -0.043771 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0431572 |
| RPL23 | ribosomal protein L23 | -0.0430486 |
| EGFR | epidermal growth factor receptor | -0.0420881 |
| RPS24 | ribosomal protein S24 | -0.0402074 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0394045 |
| HMGA1 | high mobility group AT-hook 1 | -0.0380862 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.037941 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0368961 |
| RPS8 | ribosomal protein S8 | -0.0368006 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0353805 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0353309 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0345532 |
| SRGN | serglycin | -0.0342391 |
| ZNF292 | zinc finger protein 292 | -0.0330952 |
| RPL34 | ribosomal protein L34 | -0.0322208 |
| NAV3 | neuron navigator 3 | -0.0318509 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0317678 |
| S100A11 | S100 calcium binding protein A11 | -0.0317559 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0316572 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0313262 |
| USP34 | ubiquitin specific peptidase 34 | -0.0312485 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0312106 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.031084 |
| OSMR | oncostatin M receptor | -0.0305325 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0302256 |
| PTK2 | protein tyrosine kinase 2 | -0.0292719 |
| RPS20 | ribosomal protein S20 | -0.0287328 |
| GRAMD1B | GRAM domain containing 1B | -0.0284033 |
| S100A6 | S100 calcium binding protein A6 | -0.0283572 |
| HLA-B | major histocompatibility complex, class I, B | -0.0282864 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0282393 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0281943 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0278751 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0272595 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271091 |
| DENND4A | DENN/MADD domain containing 4A | -0.0269768 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0267004 |
| RPL26 | ribosomal protein L26 | -0.0263714 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0262663 |
| RPL38 | ribosomal protein L38 | -0.0261819 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0260309 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0259914 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0258622 |
| ANXA2 | annexin A2 | -0.0254425 |
| DOCK4 | dedicator of cytokinesis 4 | -0.025289 |
| RPS23 | ribosomal protein S23 | -0.0252546 |
| RPL30 | ribosomal protein L30 | -0.0250987 |
| RPS19 | ribosomal protein S19 | -0.0248776 |
| OLA1 | Obg-like ATPase 1 | -0.024738 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0247105 |
| WWOX | WW domain containing oxidoreductase | -0.0246743 |
| RPS25 | ribosomal protein S25 | -0.0246415 |
| RPS29 | ribosomal protein S29 | -0.0246088 |
| HMGB1 | high mobility group box 1 | -0.0245432 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.02425 |
| RPL37A | ribosomal protein L37a | -0.0232358 |
| MAP1B | microtubule-associated protein 1B | -0.0231445 |
| LMNA | lamin A/C | -0.0226681 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.022625 |
| STC1 | stanniocalcin 1 | -0.0225726 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.02256 |
| AK1 | adenylate kinase 1 | -0.0224791 |
| MORF4L2 | mortality factor 4 like 2 | -0.0222621 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.0221559 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.022047 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0217554 |
| ANGPTL4 | angiopoietin-like 4 | -0.0215231 |
| RPL36 | ribosomal protein L36 | -0.021514 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.021487 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0205704 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0205549 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0204978 |
| ARF1 | ADP-ribosylation factor 1 | -0.0204853 |
