| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0750699 |
| RPS6 | ribosomal protein S6 | 0.0733555 |
| MT2A | metallothionein 2A | 0.0730596 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0722643 |
| EGFR | epidermal growth factor receptor | 0.0697002 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0666228 |
| PDE10A | phosphodiesterase 10A | 0.0605423 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0562725 |
| RBM39 | RNA binding motif protein 39 | 0.0561343 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.056078 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0549773 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0537146 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0535286 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0513384 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0507377 |
| RPS16 | ribosomal protein S16 | 0.0500351 |
| PTK2 | protein tyrosine kinase 2 | 0.0489392 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0489185 |
| SBF2 | SET binding factor 2 | 0.0486831 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0477927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0466448 |
| MKI67 | marker of proliferation Ki-67 | 0.0465845 |
| RPS3 | ribosomal protein S3 | 0.046412 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0455966 |
| YBX1 | Y box binding protein 1 | 0.0453978 |
| PHF21A | PHD finger protein 21A | 0.0448567 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0443055 |
| RTN4 | reticulon 4 | 0.0434495 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0434428 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0433701 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0430511 |
| NOP58 | NOP58 ribonucleoprotein | 0.0417447 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0401213 |
| SMYD3 | SET and MYND domain containing 3 | 0.0401121 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.039902 |
| PTGES2 | prostaglandin E synthase 2 | 0.0388128 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0386458 |
| MYOF | myoferlin | 0.0385053 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0384536 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0384339 |
| ATP13A3 | ATPase type 13A3 | 0.0383078 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0380397 |
| SUCO | SUN domain containing ossification factor | 0.0376587 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.037324 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0373225 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0372074 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0366274 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0360891 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0360239 |
| DST | dystonin | 0.0357887 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0357281 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0356722 |
| RAD51B | RAD51 paralog B | 0.0353417 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0349679 |
| TPM3 | tropomyosin 3 | 0.0349363 |
| SON | SON DNA binding protein | 0.0349113 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0344965 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.034369 |
| IGF2 | insulin-like growth factor 2 | 0.0339498 |
| GOLGA4 | golgin A4 | 0.0338912 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0335734 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0333832 |
| LAMA4 | laminin, alpha 4 | 0.0332819 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0331135 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0329406 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0328768 |
| ITGA6 | integrin, alpha 6 | 0.0328013 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0325875 |
| THOC2 | THO complex 2 | 0.0323052 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0322375 |
| CDC42SE2 | CDC42 small effector 2 | 0.0321509 |
| HELZ | helicase with zinc finger | 0.032094 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0320216 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0319197 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0318956 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0318504 |
| RPS21 | ribosomal protein S21 | 0.0317047 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0316119 |
| B2M | beta-2-microglobulin | 0.0315889 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0314525 |
| SMAD3 | SMAD family member 3 | 0.0313084 |
| RPL11 | ribosomal protein L11 | 0.0312273 |
| STAG2 | stromal antigen 2 | 0.0311837 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0311015 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0310624 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0308104 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0304633 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0299298 |
| RPL38 | ribosomal protein L38 | 0.0294182 |
| NKTR | natural killer cell triggering receptor | 0.0292834 |
| CCNY | cyclin Y | 0.0290183 |
| PRKCA | protein kinase C, alpha | 0.0290059 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0289368 |
| VCL | vinculin | 0.0288305 |
| FAT1 | FAT atypical cadherin 1 | 0.0287263 |
| PTMA | prothymosin, alpha | 0.028464 |
| H1-0 | H1.0 linker histone | 0.0284551 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0283431 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0283315 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0282145 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT17 | keratin 17, type I | -0.140228 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.128135 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.121765 |
| LAMB3 | laminin, beta 3 | -0.118886 |
| FN1 | fibronectin 1 | -0.108811 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.105889 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.104129 |
| LMO7 | LIM domain 7 | -0.104118 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.102704 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.100623 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.098931 |
| S100A9 | S100 calcium binding protein A9 | -0.0911658 |
| MYO1E | myosin IE | -0.0907353 |
| TMSB10 | thymosin beta 10 | -0.0769046 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0762327 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0746193 |
| ATOSA | atos homolog A | -0.0743242 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0740844 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0733544 |
| KYNU | kynureninase | -0.0721756 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0684739 |
| ABHD17C | abhydrolase domain containing 17C | -0.0677906 |
| EZR | ezrin | -0.0662936 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0658197 |
| ANXA2 | annexin A2 | -0.0644392 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0617624 |
| TPM4 | tropomyosin 4 | -0.0615235 |
| MUC16 | mucin 16, cell surface associated | -0.060999 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0603863 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0594941 |
| TJP1 | tight junction protein 1 | -0.0562118 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0555596 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0551482 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0546788 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0543385 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0524453 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0516392 |
| CDK13 | cyclin-dependent kinase 13 | -0.0515867 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0509292 |
| FLNB | filamin B, beta | -0.049461 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0490875 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0477644 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0477035 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0463911 |
| SVIL | supervillin | -0.045891 |
| CDH13 | cadherin 13 | -0.0448981 |
| POTEF | POTE ankyrin domain family, member F | -0.0448763 |
| CCNI | cyclin I | -0.044574 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0442645 |
| MXD1 | MAX dimerization protein 1 | -0.0438715 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0437545 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0432936 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0428927 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0424706 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0424114 |
| RPL35A | ribosomal protein L35a | -0.0416708 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0408721 |
| GOLGB1 | golgin B1 | -0.0405335 |
| LAMC2 | laminin, gamma 2 | -0.0403999 |
| RND3 | Rho family GTPase 3 | -0.0391431 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0390835 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0387346 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0383007 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0381526 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0375607 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0374638 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0369264 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0368311 |
| FTL | ferritin, light polypeptide | -0.0363083 |
| ACTG1 | actin gamma 1 | -0.0360543 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0359276 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.035687 |
| PDLIM5 | PDZ and LIM domain 5 | -0.035451 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0354026 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0348646 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0346354 |
| RAB10 | RAB10, member RAS oncogene family | -0.0343807 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0338275 |
| DIDO1 | death inducer-obliterator 1 | -0.0336365 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0333128 |
| TPR | translocated promoter region, nuclear basket protein | -0.0332922 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0329389 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0325885 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0325408 |
| S100A10 | S100 calcium binding protein A10 | -0.0316585 |
| RPL37 | ribosomal protein L37 | -0.03164 |
| RPL19 | ribosomal protein L19 | -0.0314931 |
| NPTN | neuroplastin | -0.0311748 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.031068 |
| QKI | QKI, KH domain containing, RNA binding | -0.030838 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.030754 |
| THBS1 | thrombospondin 1 | -0.0304893 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0303137 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0298335 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0292675 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0292094 |
| JMJD1C | jumonji domain containing 1C | -0.0291274 |
| ERBIN | erbb2 interacting protein | -0.0290856 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0289492 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0286772 |
