| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.123958 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.121576 |
| YBX3 | Y box binding protein 3 | 0.116406 |
| TXNRD1 | thioredoxin reductase 1 | 0.110472 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.108512 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.107982 |
| TPM3 | tropomyosin 3 | 0.0881921 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.084463 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0720389 |
| RAD51B | RAD51 paralog B | 0.0714247 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0635581 |
| MKI67 | marker of proliferation Ki-67 | 0.056663 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0564253 |
| KRT18 | keratin 18, type I | 0.0526344 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0509742 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.05007 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0485368 |
| RRM2 | ribonucleotide reductase M2 | 0.0462772 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0443288 |
| UBC | ubiquitin C | 0.0440066 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0437403 |
| TPI1 | triosephosphate isomerase 1 | 0.0428945 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.042702 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0395399 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0392632 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0379476 |
| AHNAK | AHNAK nucleoprotein | 0.0359242 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0356634 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0352589 |
| ANO6 | anoctamin 6 | 0.0335972 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0331211 |
| CENPF | centromere protein F, 350/400kDa | 0.0325323 |
| GOLGB1 | golgin B1 | 0.0324634 |
| DST | dystonin | 0.0312182 |
| CALD1 | caldesmon 1 | 0.0311599 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.030858 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0308255 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0307463 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303342 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.030127 |
| YBX1 | Y box binding protein 1 | 0.0301202 |
| RPL3 | ribosomal protein L3 | 0.0292199 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0291427 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0284971 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0278058 |
| RPS4X | ribosomal protein S4, X-linked | 0.0273132 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0272905 |
| OGA | O-GlcNAcase | 0.0269876 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0265584 |
| XPO1 | exportin 1 | 0.0263593 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.026136 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.025154 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0250055 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0246738 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0245043 |
| GOLT1B | golgi transport 1B | 0.0244391 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0237867 |
| JMJD1C | jumonji domain containing 1C | 0.0236607 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.023579 |
| VMP1 | vacuole membrane protein 1 | 0.0230544 |
| WBP11 | WW domain binding protein 11 | 0.0230122 |
| TPX2 | TPX2, microtubule-associated | 0.0229 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0228475 |
| RPS12 | ribosomal protein S12 | 0.0224167 |
| CEP250 | centrosomal protein 250kDa | 0.0223615 |
| ASPH | aspartate beta-hydroxylase | 0.0223392 |
| RPS7 | ribosomal protein S7 | 0.0222727 |
| IL6ST | interleukin 6 signal transducer | 0.0220645 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0219649 |
| MSH6 | mutS homolog 6 | 0.0218726 |
| STMN1 | stathmin 1 | 0.0217438 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0217288 |
| PHF21A | PHD finger protein 21A | 0.0216903 |
| DSPP | dentin sialophosphoprotein | 0.0216826 |
| RPL32 | ribosomal protein L32 | 0.0216809 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0216031 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0215459 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0214544 |
| ARRDC3 | arrestin domain containing 3 | 0.021444 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0213576 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0212634 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0212255 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0209819 |
| CTTN | cortactin | 0.0207579 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0206894 |
| RPS6 | ribosomal protein S6 | 0.0205649 |
| SFTPA2 | surfactant protein A2 | 0.0205336 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0205116 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0204964 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0204403 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0203631 |
| SETD5 | SET domain containing 5 | 0.0201634 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0201213 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0201196 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0200687 |
| RPL12 | ribosomal protein L12 | 0.0199805 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0198143 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0198113 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0197569 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0197209 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109152 |
| EGR1 | early growth response 1 | -0.096644 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0662965 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0577237 |
| ACTG1 | actin gamma 1 | -0.055941 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0530618 |
| OSMR | oncostatin M receptor | -0.0516912 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0508365 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0493959 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0492294 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0485978 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0455914 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0446387 |
| IGF2 | insulin-like growth factor 2 | -0.0445436 |
| POTEF | POTE ankyrin domain family, member F | -0.0430885 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0424202 |
| TMSB10 | thymosin beta 10 | -0.0418634 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0416458 |
| ATP11A | ATPase, class VI, type 11A | -0.041463 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0334148 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.033143 |
| HMGA2 | high mobility group AT-hook 2 | -0.0315076 |
| HLA-B | major histocompatibility complex, class I, B | -0.0303687 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0300867 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0294889 |
| VIM | vimentin | -0.0294397 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0288744 |
| IER3 | immediate early response 3 | -0.0287558 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0286323 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0286171 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0284213 |
| USP34 | ubiquitin specific peptidase 34 | -0.0284194 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0283937 |
| EGFR | epidermal growth factor receptor | -0.0279409 |
| ATG7 | autophagy related 7 | -0.0276956 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0276277 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0268731 |
| AGRN | agrin | -0.0266599 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0266577 |
| NF1 | neurofibromin 1 | -0.0265406 |
| ZNF207 | zinc finger protein 207 | -0.025759 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0257323 |
| RPL35A | ribosomal protein L35a | -0.0257132 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0254674 |
| MEF2D | myocyte enhancer factor 2D | -0.0248704 |
| RSF1 | remodeling and spacing factor 1 | -0.024807 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0238105 |
| TAPBP | TAP binding protein (tapasin) | -0.0237396 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0235931 |
| S100A11 | S100 calcium binding protein A11 | -0.0235096 |
| BSG | basigin (Ok blood group) | -0.0234056 |
| RPS24 | ribosomal protein S24 | -0.0230777 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230666 |
| FMNL2 | formin-like 2 | -0.0227108 |
| TMEM131 | transmembrane protein 131 | -0.0224552 |
| FLNA | filamin A, alpha | -0.0220718 |
| PDE10A | phosphodiesterase 10A | -0.0215464 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0212405 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0212309 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0208184 |
| RYR3 | ryanodine receptor 3 | -0.020764 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0207056 |
| RNF213 | ring finger protein 213 | -0.0205916 |
| SVIL | supervillin | -0.0205405 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0203626 |
| PTK2 | protein tyrosine kinase 2 | -0.0201199 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0200514 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0200443 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0197517 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0195549 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0193901 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0191821 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.019119 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0190587 |
| E2F3 | E2F transcription factor 3 | -0.0190349 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0188856 |
| LOXL2 | lysyl oxidase-like 2 | -0.0187163 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0186236 |
| PTMS | parathymosin | -0.018572 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0180591 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0179643 |
| PER1 | period circadian clock 1 | -0.0175466 |
| ATN1 | atrophin 1 | -0.0174781 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0173446 |
| EP400 | E1A binding protein p400 | -0.0172924 |
| BRD4 | bromodomain containing 4 | -0.0171185 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0170612 |
| RBM25 | RNA binding motif protein 25 | -0.0170603 |
| HLA-C | major histocompatibility complex, class I, C | -0.0168915 |
| PFN1 | profilin 1 | -0.0168648 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0168607 |
| WDR70 | WD repeat domain 70 | -0.0167176 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0166659 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0166496 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0164957 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0164339 |
| SMIM44 | small integral membrane protein 44 | -0.0164293 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0164008 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0162057 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0162026 |
