| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.156909 |
| VEGFA | vascular endothelial growth factor A | 0.0683792 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.060019 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0564265 |
| MSN | moesin | 0.0549635 |
| SDC4 | syndecan 4 | 0.0540122 |
| TPM3 | tropomyosin 3 | 0.0513564 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0492672 |
| ARRDC3 | arrestin domain containing 3 | 0.0476604 |
| LAMC2 | laminin, gamma 2 | 0.0465667 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0447417 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0393232 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0392043 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.035663 |
| TXNIP | thioredoxin interacting protein | 0.0328884 |
| MYO5B | myosin VB | 0.0327535 |
| EZR | ezrin | 0.0299425 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0278843 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0272704 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0268249 |
| VGLL3 | vestigial-like family member 3 | 0.0259257 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.025881 |
| RPL3 | ribosomal protein L3 | 0.0256181 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0250445 |
| DSPP | dentin sialophosphoprotein | 0.0237736 |
| BRD2 | bromodomain containing 2 | 0.0219528 |
| ANO6 | anoctamin 6 | 0.0217927 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0217256 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0216206 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0213972 |
| CD44 | CD44 molecule (Indian blood group) | 0.0209761 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0207264 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0198088 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0197122 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0195164 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0194232 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0193014 |
| RPS12 | ribosomal protein S12 | 0.0190755 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0185978 |
| ADM | adrenomedullin | 0.0182663 |
| TUFT1 | tuftelin 1 | 0.0181651 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0171384 |
| DTNA | dystrobrevin, alpha | 0.0170232 |
| FHIT | fragile histidine triad | 0.0169448 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0167733 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0165848 |
| MCL1 | myeloid cell leukemia 1 | 0.0164098 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0163666 |
| MKI67 | marker of proliferation Ki-67 | 0.0162331 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.016137 |
| RYBP | RING1 and YY1 binding protein | 0.0159892 |
| RPS2 | ribosomal protein S2 | 0.0158354 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0158035 |
| ANXA1 | annexin A1 | 0.0156356 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0156009 |
| SFTPA2 | surfactant protein A2 | 0.0155108 |
| ITGAV | integrin, alpha V | 0.0153908 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0151023 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0150874 |
| HOMER2 | homer scaffolding protein 2 | 0.0149994 |
| PCM1 | pericentriolar material 1 | 0.0149771 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0147943 |
| POTEF | POTE ankyrin domain family, member F | 0.0146854 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0145535 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.014492 |
| KIAA1217 | KIAA1217 | 0.0144027 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.014318 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0142544 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0140365 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0140024 |
| CTSB | cathepsin B | 0.0138518 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0135574 |
| CCNL1 | cyclin L1 | 0.0133946 |
| YBX1 | Y box binding protein 1 | 0.013358 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0131217 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0130333 |
| HPCAL1 | hippocalcin-like 1 | 0.012932 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0127759 |
| VMP1 | vacuole membrane protein 1 | 0.0127317 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0126654 |
| AHNAK | AHNAK nucleoprotein | 0.0126308 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0125997 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0124775 |
| RAD51B | RAD51 paralog B | 0.0123414 |
| SACK1B | scaffolding CK1 anchoring protein B | 0.0122889 |
| STK17B | serine/threonine kinase 17b | 0.0121451 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0121297 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0121117 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.012027 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0120237 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0120089 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0119904 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0119813 |
| SEPTIN9 | septin 9 | 0.0118058 |
| NPTN | neuroplastin | 0.0117982 |
| ITGA6 | integrin, alpha 6 | 0.0117686 |
| TMF1 | TATA element modulatory factor 1 | 0.011706 |
| ANXA11 | annexin A11 | 0.0116772 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0114134 |
| SLK | STE20-like kinase | 0.0113699 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.223523 |
| PTMA | prothymosin, alpha | -0.176127 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.171481 |
| ACTG1 | actin gamma 1 | -0.12907 |
| TMSB10 | thymosin beta 10 | -0.128143 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.107083 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0994033 |
| LMO7 | LIM domain 7 | -0.0987504 |
| TMSB4X | thymosin beta 4, X-linked | -0.0982885 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.089137 |
| CCND1 | cyclin D1 | -0.0868477 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0828976 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.082339 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0799714 |
| TOP1 | topoisomerase (DNA) I | -0.0795252 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0792672 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0783076 |
| FNDC3B | fibronectin type III domain containing 3B | -0.075469 |
| PGK1 | phosphoglycerate kinase 1 | -0.0750488 |
| CD2AP | CD2-associated protein | -0.0682804 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0664041 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0644069 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0643633 |
| ARF1 | ADP-ribosylation factor 1 | -0.0635058 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0627996 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0627473 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0619123 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0610612 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0603439 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.058912 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.056657 |
| CANX | calnexin | -0.0563149 |
| HMGA1 | high mobility group AT-hook 1 | -0.0555862 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0551386 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0535666 |
| GNAS | GNAS complex locus | -0.0534682 |
| TMEM123 | transmembrane protein 123 | -0.0532696 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0531664 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0528494 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0523934 |
| RPL35A | ribosomal protein L35a | -0.051611 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0507384 |
| RPL34 | ribosomal protein L34 | -0.0501659 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.050067 |
| S100A6 | S100 calcium binding protein A6 | -0.049905 |
| SQSTM1 | sequestosome 1 | -0.0490668 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0484761 |
| TMEM263 | transmembrane protein 263 | -0.0484329 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0480855 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0475838 |
| HDLBP | high density lipoprotein binding protein | -0.0475332 |
| S100A10 | S100 calcium binding protein A10 | -0.0473843 |
| ERBIN | erbb2 interacting protein | -0.0466599 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0461288 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.045412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0451812 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0449099 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0448605 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0444078 |
| KRT7 | keratin 7, type II | -0.043205 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0431143 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0429958 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0428422 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0424821 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0422969 |
| SLMAP | sarcolemma associated protein | -0.0421114 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0419505 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0418264 |
| LMNA | lamin A/C | -0.0418018 |
| CALU | calumenin | -0.0415454 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0414463 |
| TPM4 | tropomyosin 4 | -0.0408019 |
| ANXA2 | annexin A2 | -0.0406522 |
| RPS24 | ribosomal protein S24 | -0.0395175 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0394962 |
| JMJD1C | jumonji domain containing 1C | -0.0392132 |
| RRBP1 | ribosome binding protein 1 | -0.0388141 |
| NF1 | neurofibromin 1 | -0.0387137 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0382972 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0381819 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0379504 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0376749 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0374155 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0374077 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.037312 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.037131 |
| ZNF207 | zinc finger protein 207 | -0.0368813 |
| GOLGA4 | golgin A4 | -0.0364399 |
| MYO6 | myosin VI | -0.0361746 |
| MAP4 | microtubule-associated protein 4 | -0.0361615 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0360856 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0359539 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0358759 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0358546 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0357632 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0357538 |
| PARD3 | par-3 family cell polarity regulator | -0.035518 |
| CAVIN1 | caveolae associated protein 1 | -0.0355027 |
| COPA | coatomer protein complex, subunit alpha | -0.0354937 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0353097 |
