| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.156901 |
| PM20D1 | peptidase M20 domain containing 1 | 0.138081 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.11967 |
| MCL1 | myeloid cell leukemia 1 | 0.0882292 |
| DST | dystonin | 0.0875571 |
| RPS6 | ribosomal protein S6 | 0.0774051 |
| ASPH | aspartate beta-hydroxylase | 0.0672285 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0625299 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0616533 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0554868 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0518493 |
| FN1 | fibronectin 1 | 0.0516138 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0513154 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0510531 |
| RGS2 | regulator of G-protein signaling 2 | 0.0507957 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0456473 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0433626 |
| KYNU | kynureninase | 0.042701 |
| CENPF | centromere protein F, 350/400kDa | 0.0424406 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0419719 |
| SFTPA2 | surfactant protein A2 | 0.0409171 |
| MT2A | metallothionein 2A | 0.0398716 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0394101 |
| INHBA | inhibin, beta A | 0.0393924 |
| RPL3 | ribosomal protein L3 | 0.0387105 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0380027 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0374989 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0370672 |
| GNAS | GNAS complex locus | 0.0368551 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0360823 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0360715 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0357528 |
| RPS12 | ribosomal protein S12 | 0.0351709 |
| VIM | vimentin | 0.0348129 |
| EGR1 | early growth response 1 | 0.0347133 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0345794 |
| HLA-A | major histocompatibility complex, class I, A | 0.0345294 |
| FNDC3A | fibronectin type III domain containing 3A | 0.034377 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0338106 |
| CLU | clusterin | 0.0337468 |
| VCL | vinculin | 0.0334229 |
| TPM3 | tropomyosin 3 | 0.0331866 |
| B2M | beta-2-microglobulin | 0.0325656 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0324406 |
| MSN | moesin | 0.0320711 |
| MKI67 | marker of proliferation Ki-67 | 0.03163 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0308222 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0307975 |
| IL6 | interleukin 6 | 0.0297556 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0297029 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0294896 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0280978 |
| NDRG1 | N-myc downstream regulated 1 | 0.0280881 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0280598 |
| TBXT | T-box transcription factor T | 0.0279374 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0278896 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0272928 |
| UBC | ubiquitin C | 0.0272924 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0272014 |
| EPHA4 | EPH receptor A4 | 0.0269885 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0269162 |
| LAMB1 | laminin, beta 1 | 0.0268992 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0268004 |
| TMF1 | TATA element modulatory factor 1 | 0.0265811 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0265125 |
| PYGL | phosphorylase, glycogen, liver | 0.0262648 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0262085 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0259873 |
| PCBP3 | poly(rC) binding protein 3 | 0.0259503 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0254148 |
| CHL1 | cell adhesion molecule L1-like | 0.0252742 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0250986 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0249845 |
| GOLGB1 | golgin B1 | 0.0245586 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0245055 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0243595 |
| RIGI | RNA sensor RIG-I | 0.0242791 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0239428 |
| STC1 | stanniocalcin 1 | 0.0235753 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0231745 |
| SLK | STE20-like kinase | 0.0225486 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0222837 |
| SYAP1 | synapse associated protein 1 | 0.0221122 |
| ARRDC3 | arrestin domain containing 3 | 0.0216662 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0216557 |
| MAP7 | microtubule-associated protein 7 | 0.0215818 |
| MT1X | metallothionein 1X | 0.021387 |
| RPS2 | ribosomal protein S2 | 0.0213152 |
| ITGA6 | integrin, alpha 6 | 0.0212602 |
| YBX3 | Y box binding protein 3 | 0.0210453 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0208507 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0207849 |
| TPI1 | triosephosphate isomerase 1 | 0.0205979 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0205531 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0205124 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0204262 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0202635 |
| NCOR2 | nuclear receptor corepressor 2 | 0.020253 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0202268 |
| YBX1 | Y box binding protein 1 | 0.0192232 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.214022 |
| TXNRD1 | thioredoxin reductase 1 | -0.115015 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.104887 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0983751 |
| RPS24 | ribosomal protein S24 | -0.0924453 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0755752 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0697186 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0685437 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0653201 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0608467 |
| EFNA5 | ephrin-A5 | -0.0597933 |
| TNPO1 | transportin 1 | -0.0595693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0591525 |
| NEK7 | NIMA-related kinase 7 | -0.0577178 |
| CDH13 | cadherin 13 | -0.0556268 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0549361 |
| RTN4 | reticulon 4 | -0.0542271 |
| GDA | guanine deaminase | -0.0520177 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0509198 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0503077 |
| USP3 | ubiquitin specific peptidase 3 | -0.0484706 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0475389 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0464437 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0459333 |
| SPAG9 | sperm associated antigen 9 | -0.0444632 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0443371 |
| ACTG1 | actin gamma 1 | -0.0442559 |
| RPL23 | ribosomal protein L23 | -0.0421731 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0421396 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0420128 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0412045 |
| RPLP0 | ribosomal protein, large, P0 | -0.0410953 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0400198 |
| NF1 | neurofibromin 1 | -0.0399125 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0393617 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0390964 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0388684 |
| PLCB4 | phospholipase C, beta 4 | -0.0377593 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0372956 |
| RBM39 | RNA binding motif protein 39 | -0.0372697 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.036862 |
| RPL35A | ribosomal protein L35a | -0.0359728 |
| WDR43 | WD repeat domain 43 | -0.0353848 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0352018 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0351121 |
| RPLP1 | ribosomal protein, large, P1 | -0.0350717 |
| USP34 | ubiquitin specific peptidase 34 | -0.0349808 |
| PTK2 | protein tyrosine kinase 2 | -0.034765 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0346375 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0345078 |
| NRCAM | neuronal cell adhesion molecule | -0.0343115 |
| OLA1 | Obg-like ATPase 1 | -0.0338223 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0336029 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0334865 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0331003 |
| SMYD3 | SET and MYND domain containing 3 | -0.0324584 |
| ENAH | enabled homolog (Drosophila) | -0.0324473 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0324285 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0320565 |
| ZNF207 | zinc finger protein 207 | -0.0317314 |
| PALLD | palladin, cytoskeletal associated protein | -0.0307679 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0305402 |
| MED13 | mediator complex subunit 13 | -0.0304534 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0304247 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0300349 |
| COG5 | component of oligomeric golgi complex 5 | -0.0298153 |
| NCKAP1 | NCK-associated protein 1 | -0.0297845 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0295634 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0295277 |
| ARF1 | ADP-ribosylation factor 1 | -0.0294264 |
| ATP13A3 | ATPase type 13A3 | -0.0289057 |
| IPO7 | importin 7 | -0.028777 |
| PGK1 | phosphoglycerate kinase 1 | -0.0284197 |
| NBAS | neuroblastoma amplified sequence | -0.0282166 |
| GRAMD1B | GRAM domain containing 1B | -0.0281465 |
| ANKRD17 | ankyrin repeat domain 17 | -0.028062 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0279069 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0275232 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0275101 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0274166 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0273464 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0271395 |
| GPHN | gephyrin | -0.0270717 |
| MED13L | mediator complex subunit 13-like | -0.0270415 |
| TCERG1 | transcription elongation regulator 1 | -0.0269247 |
| MATR3 | matrin 3 | -0.026849 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0268246 |
| MORF4L2 | mortality factor 4 like 2 | -0.0267256 |
| TMEM131 | transmembrane protein 131 | -0.0266496 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0266458 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.026142 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0261078 |
| PDE10A | phosphodiesterase 10A | -0.0259048 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0258129 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0256822 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0256352 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0254681 |
| RPL9 | ribosomal protein L9 | -0.0253541 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0252234 |
| TSC22D2 | TSC22 domain family, member 2 | -0.024909 |
