| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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195 genes differentially expressed following the Bicalutamide_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.281217 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.227831 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.225017 |
| FN1 | fibronectin 1 | 0.220788 |
| DST | dystonin | 0.152918 |
| LSAMP | limbic system-associated membrane protein | 0.145289 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.140924 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.114071 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.105017 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0996074 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0880443 |
| EFNA5 | ephrin-A5 | 0.0873275 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0842043 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0841507 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0811234 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0764353 |
| JMJD1C | jumonji domain containing 1C | 0.073588 |
| CDH13 | cadherin 13 | 0.0699192 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0688661 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0653198 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0640176 |
| RORA | RAR-related orphan receptor A | 0.0636744 |
| TXNIP | thioredoxin interacting protein | 0.0607004 |
| RUNX1 | runt-related transcription factor 1 | 0.0606218 |
| AUTS2 | autism susceptibility candidate 2 | 0.0605807 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0591504 |
| DSPP | dentin sialophosphoprotein | 0.0587636 |
| EGFR | epidermal growth factor receptor | 0.0571962 |
| DTNA | dystrobrevin, alpha | 0.0551896 |
| BPTF | bromodomain PHD finger transcription factor | 0.0548898 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0541612 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0481787 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0481455 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0472803 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0460007 |
| GDA | guanine deaminase | 0.0459173 |
| IGF2 | insulin-like growth factor 2 | 0.0422697 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.041936 |
| RNF213 | ring finger protein 213 | 0.04159 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0389285 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0384144 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0377986 |
| ITGAV | integrin, alpha V | 0.0375529 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0374636 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0360819 |
| SPAG9 | sperm associated antigen 9 | 0.0359493 |
| EXOC6B | exocyst complex component 6B | 0.0355541 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0348453 |
| MEF2A | myocyte enhancer factor 2A | 0.0331705 |
| NAV2 | neuron navigator 2 | 0.03279 |
| ASPH | aspartate beta-hydroxylase | 0.0325197 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.032508 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0310427 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.030859 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0307348 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0288682 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0280774 |
| VIM | vimentin | 0.0277365 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0258873 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0256828 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0255351 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0255002 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0247316 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0243158 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0241441 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0236772 |
| MYO1E | myosin IE | 0.0219124 |
| NDRG1 | N-myc downstream regulated 1 | 0.0213106 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0205317 |
| PDE10A | phosphodiesterase 10A | 0.0204733 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0204147 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0196575 |
| KIAA1217 | KIAA1217 | 0.0195093 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.019105 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0188939 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0182121 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0176849 |
| GNAS | GNAS complex locus | 0.0170818 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.017064 |
| MYO10 | myosin X | 0.0154548 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0140493 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0139886 |
| LDHA | lactate dehydrogenase A | 0.0135775 |
| FAM13A | family with sequence similarity 13, member A | 0.0124834 |
| SETD5 | SET domain containing 5 | 0.0123459 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0116871 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00989961 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00972304 |
| MED13L | mediator complex subunit 13-like | 0.00945177 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00679552 |
| MSI2 | musashi RNA-binding protein 2 | 0.00676924 |
| H3-3B | H3.3 histone B | 0.0064416 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.00496161 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00225375 |
| EXT1 | exostosin glycosyltransferase 1 | 4.4605E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | -0.100028 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0957587 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0897052 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0848059 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0847937 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0824586 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0817723 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0795953 |
| CDK19 | cyclin-dependent kinase 19 | -0.0764627 |
| VCL | vinculin | -0.0746756 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0721646 |
| RSF1 | remodeling and spacing factor 1 | -0.0715911 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0676634 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0669691 |
| MYOF | myoferlin | -0.0664789 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0652086 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0644877 |
| ANXA2 | annexin A2 | -0.0642779 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0637032 |
| PKM | pyruvate kinase, muscle | -0.0619277 |
| CALU | calumenin | -0.0612663 |
| ACTG1 | actin gamma 1 | -0.0612546 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.061234 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0609608 |
| RPS8 | ribosomal protein S8 | -0.0592998 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0590042 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0589939 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0581767 |
| RPS6 | ribosomal protein S6 | -0.0580322 |
| SLTM | SAFB-like, transcription modulator | -0.0578388 |
| OGA | O-GlcNAcase | -0.0562161 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0555882 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0547808 |
| ENO1 | enolase 1, (alpha) | -0.0537349 |
| FLNB | filamin B, beta | -0.0531691 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0528886 |
| RBM39 | RNA binding motif protein 39 | -0.0518046 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0516762 |
| RPL15 | ribosomal protein L15 | -0.0508524 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0506631 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0501907 |
| GOLGA4 | golgin A4 | -0.0501247 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0498526 |
| LAMA4 | laminin, alpha 4 | -0.0493348 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0492899 |
| CLTC | clathrin, heavy chain (Hc) | -0.0474654 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0462868 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0450416 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0437918 |
| RTN4 | reticulon 4 | -0.0436864 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0424073 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0423083 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0417663 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0412808 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.039597 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0391857 |
| SMYD3 | SET and MYND domain containing 3 | -0.038931 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0374182 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0372251 |
| PDE8A | phosphodiesterase 8A | -0.0370179 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0367191 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0357197 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.035417 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0339917 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0334474 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0329715 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0316577 |
| PGK1 | phosphoglycerate kinase 1 | -0.0312724 |
| GPC6 | glypican 6 | -0.0298526 |
| FOXP1 | forkhead box P1 | -0.0291277 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0291132 |
| CD2AP | CD2-associated protein | -0.0281738 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267551 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0246688 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0232728 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0220031 |
| ZNF292 | zinc finger protein 292 | -0.0216692 |
| NF1 | neurofibromin 1 | -0.0212253 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0205435 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0200611 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0200305 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0188897 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.017464 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0172796 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0167418 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0151579 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.015039 |
| TXNRD1 | thioredoxin reductase 1 | -0.0148631 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0144048 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.013062 |
| DSCAM | Down syndrome cell adhesion molecule | -0.010723 |
| FNIP1 | folliculin interacting protein 1 | -0.0106408 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0102748 |
| FNDC3A | fibronectin type III domain containing 3A | -0.00998666 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0093544 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00930357 |
| VMP1 | vacuole membrane protein 1 | -0.00795222 |
| FTL | ferritin, light polypeptide | -0.00707264 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00679592 |
| GOLGB1 | golgin B1 | -0.00634491 |
