| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bicalutamide_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.084089 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0807307 |
| HDAC9 | histone deacetylase 9 | 0.0476094 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.047439 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0412101 |
| RFPL4B | ret finger protein-like 4B | 0.0355993 |
| CFL2 | cofilin 2 (muscle) | 0.0353013 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0348188 |
| PHIP | pleckstrin homology domain interacting protein | 0.033384 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0331348 |
| PDGFC | platelet derived growth factor C | 0.0312573 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0302053 |
| H1-4 | H1.4 linker histone, cluster member | 0.0296553 |
| RPLP0 | ribosomal protein, large, P0 | 0.0294473 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0292269 |
| MEIS2 | Meis homeobox 2 | 0.0291051 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0290257 |
| FIGN | fidgetin | 0.0289735 |
| MTF2 | metal response element binding transcription factor 2 | 0.0284335 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0279303 |
| COG5 | component of oligomeric golgi complex 5 | 0.0261938 |
| PCDH18 | protocadherin 18 | 0.0256993 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0252011 |
| CCNA2 | cyclin A2 | 0.0251457 |
| PHF21A | PHD finger protein 21A | 0.0239355 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0238515 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0232581 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0227313 |
| H1-0 | H1.0 linker histone | 0.0226354 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0224035 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0216672 |
| TMEM64 | transmembrane protein 64 | 0.0215807 |
| TENM2 | teneurin transmembrane protein 2 | 0.021469 |
| CENPF | centromere protein F, 350/400kDa | 0.0212952 |
| MEMO1 | mediator of cell motility 1 | 0.0212416 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0202689 |
| SIK3 | SIK family kinase 3 | 0.0200205 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.0199633 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0195181 |
| CDC5L | cell division cycle 5-like | 0.0194489 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0193061 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0192251 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.01915 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0191474 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.018966 |
| ANXA5 | annexin A5 | 0.0189464 |
| PROS1 | protein S (alpha) | 0.0186726 |
| SFTPA2 | surfactant protein A2 | 0.0185376 |
| PEG10 | paternally expressed 10 | 0.0184532 |
| FBXO11 | F-box protein 11 | 0.0183757 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0182862 |
| ENAH | enabled homolog (Drosophila) | 0.018265 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0182281 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0181558 |
| ZNF292 | zinc finger protein 292 | 0.0180928 |
| MKI67 | marker of proliferation Ki-67 | 0.0180417 |
| RO60 | Ro60, Y RNA binding protein | 0.0176661 |
| GOLM2 | golgi membrane protein 2 | 0.0176052 |
| RNF13 | ring finger protein 13 | 0.0175395 |
| DST | dystonin | 0.017467 |
| ATL2 | atlastin GTPase 2 | 0.0172709 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0170462 |
| ANXA1 | annexin A1 | 0.0169831 |
| PRR11 | proline rich 11 | 0.0169597 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0167067 |
| NUMB | numb homolog (Drosophila) | 0.0165891 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0165814 |
| CRTAP | cartilage associated protein | 0.0165467 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0164392 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0164352 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0163193 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.016287 |
| CENPE | centromere protein E, 312kDa | 0.0162232 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0161791 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0158272 |
| TPTE | transmembrane phosphatase with tensin homology | 0.0157485 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0156786 |
| ATG5 | autophagy related 5 | 0.0156186 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0156148 |
| TPX2 | TPX2, microtubule-associated | 0.0155464 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0155446 |
| RAI1 | retinoic acid induced 1 | 0.0155398 |
| VCL | vinculin | 0.0155074 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0153719 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0153578 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0153063 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0152979 |
| CDCA2 | cell division cycle associated 2 | 0.0152645 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0152217 |
| JMJD1C | jumonji domain containing 1C | 0.0151861 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0148475 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0148064 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0148027 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0147474 |
| ZFR | zinc finger RNA binding protein | 0.0146727 |
| CERT1 | ceramide transporter 1 | 0.0146509 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.014539 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0144572 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0144023 |
| PDS5A | PDS5 cohesin associated factor A | 0.0143948 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.102931 |
| TMSB10 | thymosin beta 10 | -0.0975695 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0848757 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0774059 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0658539 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0643513 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0628389 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0552746 |
| VIM | vimentin | -0.0534577 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0529077 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0528212 |
| ENO1 | enolase 1, (alpha) | -0.0499258 |
| COL5A2 | collagen, type V, alpha 2 | -0.0493404 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.049202 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0482021 |
| RPL23 | ribosomal protein L23 | -0.0479587 |
| MYO10 | myosin X | -0.047081 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0463338 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0460557 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0455503 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0450411 |
| NDRG1 | N-myc downstream regulated 1 | -0.0443369 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0429079 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0423534 |
| RPS8 | ribosomal protein S8 | -0.0418027 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.040219 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0396769 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0373735 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0368582 |
| RPS27A | ribosomal protein S27a | -0.036828 |
| PRELID2 | PRELI domain containing 2 | -0.0358733 |
| PCDH9 | protocadherin 9 | -0.0356619 |
| CADM2 | cell adhesion molecule 2 | -0.035251 |
| HMGB1 | high mobility group box 1 | -0.0352229 |
| HMCN1 | hemicentin 1 | -0.0337636 |
| ACTG1 | actin gamma 1 | -0.0324402 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0323152 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0322446 |
| SET | SET nuclear proto-oncogene | -0.0321436 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0319051 |
| UBC | ubiquitin C | -0.0318555 |
| PTMA | prothymosin, alpha | -0.031597 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0310517 |
| ITGAV | integrin, alpha V | -0.0305292 |
| MED13L | mediator complex subunit 13-like | -0.0305035 |
| RPS13 | ribosomal protein S13 | -0.0300261 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0296051 |
| RPS16 | ribosomal protein S16 | -0.0295653 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0288313 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0283339 |
| THBS1 | thrombospondin 1 | -0.0279943 |
| UTRN | utrophin | -0.027919 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.027901 |
| CALCR | calcitonin receptor | -0.0278386 |
| RPS3 | ribosomal protein S3 | -0.0278113 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0273334 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0272583 |
| ACTN4 | actinin, alpha 4 | -0.0271137 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0270686 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0268763 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0264763 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0263057 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0260292 |
| GPC3 | glypican 3 | -0.0259691 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0257076 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0254586 |
| S100A10 | S100 calcium binding protein A10 | -0.0254047 |
| RPLP2 | ribosomal protein, large, P2 | -0.0249869 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0248219 |
| RAD51B | RAD51 paralog B | -0.024642 |
| PKM | pyruvate kinase, muscle | -0.0241199 |
| TJP1 | tight junction protein 1 | -0.0240806 |
| USP53 | ubiquitin specific peptidase 53 | -0.0240603 |
| FLNB | filamin B, beta | -0.0240369 |
| PCDH7 | protocadherin 7 | -0.023975 |
| RAB30 | RAB30, member RAS oncogene family | -0.0239425 |
| RPL5 | ribosomal protein L5 | -0.0239005 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0237852 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0236244 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0235895 |
| PGK1 | phosphoglycerate kinase 1 | -0.023482 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0234595 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0234313 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0233761 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0231925 |
| TOP1 | topoisomerase (DNA) I | -0.0230991 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.023064 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0230188 |
| DENND1A | DENN/MADD domain containing 1A | -0.0225951 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0225525 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0223813 |
| LDHA | lactate dehydrogenase A | -0.022231 |
| RBM39 | RNA binding motif protein 39 | -0.0221777 |
| GLI3 | GLI family zinc finger 3 | -0.022055 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0220115 |
| GSPT1 | G1 to S phase transition 1 | -0.0219823 |
| LMNA | lamin A/C | -0.0219502 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0219224 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0218465 |
| ADGRL1 | adhesion G protein-coupled receptor L1 | -0.0217749 |
