| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bicalutamide_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0965401 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0964913 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0918283 |
| ZNF608 | zinc finger protein 608 | 0.0762464 |
| TXNRD1 | thioredoxin reductase 1 | 0.0622427 |
| VCL | vinculin | 0.0605393 |
| PKM | pyruvate kinase, muscle | 0.0571443 |
| PRELID2 | PRELI domain containing 2 | 0.0562746 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0548032 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0540992 |
| TJP1 | tight junction protein 1 | 0.0510427 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0485953 |
| EZR | ezrin | 0.0438712 |
| TMEM65 | transmembrane protein 65 | 0.042388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0387161 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0360714 |
| MACROD2 | MACRO domain containing 2 | 0.0343038 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0328357 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0328095 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0327119 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0316973 |
| RPL3 | ribosomal protein L3 | 0.0313622 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.031329 |
| ASPH | aspartate beta-hydroxylase | 0.0312404 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0301711 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0287287 |
| FNIP1 | folliculin interacting protein 1 | 0.028685 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0286086 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0280697 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0275141 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0268637 |
| EFNA5 | ephrin-A5 | 0.0258927 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0246704 |
| FHIT | fragile histidine triad | 0.024613 |
| GOLGB1 | golgin B1 | 0.0245479 |
| SMYD3 | SET and MYND domain containing 3 | 0.0241784 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0238453 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0238119 |
| TXNIP | thioredoxin interacting protein | 0.0237769 |
| SFTPA2 | surfactant protein A2 | 0.0236854 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0236344 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0234686 |
| PDGFC | platelet derived growth factor C | 0.0234198 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0233605 |
| AHNAK | AHNAK nucleoprotein | 0.0229693 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0228702 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0225824 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0221983 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0221247 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0217973 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0213736 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.0212526 |
| TMF1 | TATA element modulatory factor 1 | 0.0210726 |
| USP47 | ubiquitin specific peptidase 47 | 0.0209804 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0209204 |
| ZNF638 | zinc finger protein 638 | 0.0208888 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0207868 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0206326 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0202109 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.020058 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0200196 |
| ARRDC3 | arrestin domain containing 3 | 0.0199717 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0195171 |
| PYGB | phosphorylase, glycogen; brain | 0.0193383 |
| YEATS2 | YEATS domain containing 2 | 0.0192344 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0192312 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0188541 |
| PLK2 | polo-like kinase 2 | 0.0187155 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187047 |
| GOLGA4 | golgin A4 | 0.0186062 |
| ZNF217 | zinc finger protein 217 | 0.0182987 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0182924 |
| FLNB | filamin B, beta | 0.0180896 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0180749 |
| CDK19 | cyclin-dependent kinase 19 | 0.0179355 |
| METTL15 | methyltransferase like 15 | 0.0178086 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0176477 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0174674 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0172922 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0171133 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0168804 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0168199 |
| SBF2 | SET binding factor 2 | 0.0167247 |
| ANXA3 | annexin A3 | 0.0166929 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.016485 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0163034 |
| UBC | ubiquitin C | 0.016189 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0159337 |
| SNX14 | sorting nexin 14 | 0.0158432 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0158379 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0158041 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0158014 |
| PLPP3 | phospholipid phosphatase 3 | 0.0157507 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0157168 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0153173 |
| USP34 | ubiquitin specific peptidase 34 | 0.0152955 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0151441 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0151176 |
| PHF21A | PHD finger protein 21A | 0.0150705 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0148461 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.193831 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113583 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.103646 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0849929 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0844525 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0778243 |
| FOXP1 | forkhead box P1 | -0.0768045 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0639636 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.06335 |
| BMP10 | bone morphogenetic protein 10 | -0.0632514 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0593838 |
| RPL35A | ribosomal protein L35a | -0.0571606 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.055546 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0522589 |
| RPS8 | ribosomal protein S8 | -0.0487869 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.047314 |
| ACTG1 | actin gamma 1 | -0.046188 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0454425 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0424773 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0423014 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.040558 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0403052 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0390247 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0387163 |
| DIAPH3 | diaphanous-related formin 3 | -0.0387156 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0373671 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0368677 |
| NUP58 | nucleoporin 58 | -0.0353404 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0348533 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0345541 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0331186 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0325479 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0323176 |
| RHEB | Ras homolog enriched in brain | -0.0318757 |
| ECT2 | epithelial cell transforming 2 | -0.0314286 |
| RPL34 | ribosomal protein L34 | -0.0313319 |
| RPS24 | ribosomal protein S24 | -0.0313137 |
| HMGB1 | high mobility group box 1 | -0.0304174 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0303868 |
| RPL13A | ribosomal protein L13a | -0.0298805 |
| RPLP1 | ribosomal protein, large, P1 | -0.0292082 |
| NEBL | nebulette | -0.0287708 |
| RPS19 | ribosomal protein S19 | -0.0286488 |
| RPL23 | ribosomal protein L23 | -0.028138 |
| ZNF438 | zinc finger protein 438 | -0.0279126 |
| B2M | beta-2-microglobulin | -0.0273282 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0272496 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0271403 |
| DPYD | dihydropyrimidine dehydrogenase | -0.027121 |
| KIF5B | kinesin family member 5B | -0.0268341 |
| RPL5 | ribosomal protein L5 | -0.0265287 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0264201 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260159 |
| RBM39 | RNA binding motif protein 39 | -0.026001 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0259091 |
| MATR3 | matrin 3 | -0.0258483 |
| RAB1A | RAB1A, member RAS oncogene family | -0.025833 |
| RBM8A | RNA binding motif protein 8A | -0.0256837 |
| GLI3 | GLI family zinc finger 3 | -0.0255265 |
| MKI67 | marker of proliferation Ki-67 | -0.0252844 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0251284 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249674 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0247929 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0247684 |
| PTK2 | protein tyrosine kinase 2 | -0.0244907 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0244573 |
| RPL31 | ribosomal protein L31 | -0.0244412 |
| RPS21 | ribosomal protein S21 | -0.0243183 |
| RLF | rearranged L-myc fusion | -0.0243181 |
| PARD3 | par-3 family cell polarity regulator | -0.0243146 |
| USP3 | ubiquitin specific peptidase 3 | -0.0239864 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0239586 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0238353 |
| CUX1 | cut-like homeobox 1 | -0.0235549 |
| RPS3 | ribosomal protein S3 | -0.0234565 |
| DEK | DEK proto-oncogene | -0.0233997 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0233865 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0232628 |
| PDE7B | phosphodiesterase 7B | -0.0230284 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0229604 |
| RPL38 | ribosomal protein L38 | -0.0227771 |
| RPL37A | ribosomal protein L37a | -0.022706 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0226991 |
| SEPTIN7 | septin 7 | -0.0223978 |
| RPL36 | ribosomal protein L36 | -0.0220018 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0219592 |
| ENO1 | enolase 1, (alpha) | -0.0218419 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0217188 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0216285 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0215417 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0214642 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0214105 |
| RPS25 | ribosomal protein S25 | -0.0212066 |
| IPO7 | importin 7 | -0.0211775 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0210544 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.020784 |
| PKP4 | plakophilin 4 | -0.0207828 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0207633 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0206795 |