| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.220914 |
| VCL | vinculin | 0.13802 |
| FN1 | fibronectin 1 | 0.105417 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.079403 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0752149 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0657461 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0628732 |
| DST | dystonin | 0.0579947 |
| ARRDC3 | arrestin domain containing 3 | 0.0512345 |
| SFTPA2 | surfactant protein A2 | 0.0510223 |
| VMP1 | vacuole membrane protein 1 | 0.0495312 |
| BICC1 | BicC family RNA binding protein 1 | 0.0431348 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0426053 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0408847 |
| TXNIP | thioredoxin interacting protein | 0.0384035 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0380971 |
| PALLD | palladin, cytoskeletal associated protein | 0.0375773 |
| OGA | O-GlcNAcase | 0.0375025 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0372879 |
| ATXN1 | ataxin 1 | 0.0371616 |
| MKI67 | marker of proliferation Ki-67 | 0.0367239 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0364545 |
| HDAC9 | histone deacetylase 9 | 0.0363819 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0357922 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0354328 |
| RIGI | RNA sensor RIG-I | 0.0352301 |
| MYOF | myoferlin | 0.0351015 |
| CENPF | centromere protein F, 350/400kDa | 0.034609 |
| MSN | moesin | 0.0339527 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0329756 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0301878 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0297431 |
| KYNU | kynureninase | 0.0296829 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0289083 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0285036 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.027502 |
| CCNL1 | cyclin L1 | 0.0271917 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0269387 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0268118 |
| DSCAM | Down syndrome cell adhesion molecule | 0.026798 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0260081 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0259736 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0259519 |
| FNIP1 | folliculin interacting protein 1 | 0.024895 |
| VEGFA | vascular endothelial growth factor A | 0.0246813 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0238485 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0234084 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0233855 |
| ZNF608 | zinc finger protein 608 | 0.0227894 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0226765 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0225164 |
| CLIC4 | chloride intracellular channel 4 | 0.0221556 |
| OPTN | optineurin | 0.0220287 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0220166 |
| MX1 | MX dynamin-like GTPase 1 | 0.0216005 |
| FLNB | filamin B, beta | 0.0215692 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0214749 |
| CALD1 | caldesmon 1 | 0.0206528 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0206255 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0205585 |
| PLPP6 | phospholipid phosphatase 6 | 0.0204273 |
| JMJD1C | jumonji domain containing 1C | 0.0202512 |
| TGFB2 | transforming growth factor, beta 2 | 0.020217 |
| SBF2 | SET binding factor 2 | 0.0200746 |
| CUL4B | cullin 4B | 0.0194425 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0191571 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0191117 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0190949 |
| FHIT | fragile histidine triad | 0.0187569 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0185353 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0185253 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0184144 |
| TPM3 | tropomyosin 3 | 0.0183524 |
| FRMD5 | FERM domain containing 5 | 0.0181783 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0181531 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0180106 |
| NABP1 | nucleic acid binding protein 1 | 0.0179287 |
| ANLN | anillin, actin binding protein | 0.0178934 |
| AHR | aryl hydrocarbon receptor | 0.017836 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0175965 |
| DIAPH3 | diaphanous-related formin 3 | 0.0175119 |
| UBC | ubiquitin C | 0.0174689 |
| TPX2 | TPX2, microtubule-associated | 0.0172551 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0172471 |
| GPC6 | glypican 6 | 0.0172166 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0171666 |
| COL1A2 | collagen, type I, alpha 2 | 0.017086 |
| SP100 | SP100 nuclear antigen | 0.0169421 |
| TRIM38 | tripartite motif containing 38 | 0.0169351 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0164383 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0164374 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0163686 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0163375 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0163033 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0161493 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.016142 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0160726 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0158117 |
| SDC4 | syndecan 4 | 0.0156783 |
| CREBRF | CREB3 regulatory factor | 0.0156758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.28431 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.152531 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.129891 |
| CD44 | CD44 molecule (Indian blood group) | -0.0964087 |
| IER3 | immediate early response 3 | -0.0872221 |
| CDH13 | cadherin 13 | -0.0833088 |
| GLIS3 | GLIS family zinc finger 3 | -0.08225 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0785832 |
| HLA-B | major histocompatibility complex, class I, B | -0.071761 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0713876 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.070993 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.06906 |
| PGK1 | phosphoglycerate kinase 1 | -0.0679433 |
| HMGA2 | high mobility group AT-hook 2 | -0.0678162 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.065929 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0649258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0643674 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0637118 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0632373 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0604187 |
| TMSB10 | thymosin beta 10 | -0.0545149 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0531068 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0527856 |
| FTL | ferritin, light polypeptide | -0.0513679 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.050819 |
| STC1 | stanniocalcin 1 | -0.0503704 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0496831 |
| EGFR | epidermal growth factor receptor | -0.0486117 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0466505 |
| TMSB4X | thymosin beta 4, X-linked | -0.0464833 |
| CADM1 | cell adhesion molecule 1 | -0.0460947 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0432246 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0431854 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0415439 |
| RAI14 | retinoic acid induced 14 | -0.0407469 |
| HLA-A | major histocompatibility complex, class I, A | -0.0405529 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0393155 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0388411 |
| LDHA | lactate dehydrogenase A | -0.0380178 |
| LOX | lysyl oxidase | -0.0368268 |
| RPS8 | ribosomal protein S8 | -0.0367082 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0366309 |
| HLA-E | major histocompatibility complex, class I, E | -0.0366287 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0366077 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0361878 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0353887 |
| RPL23 | ribosomal protein L23 | -0.0353258 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0345508 |
| NDRG1 | N-myc downstream regulated 1 | -0.0344173 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0340947 |
| HMGA1 | high mobility group AT-hook 1 | -0.0339342 |
| ACTG1 | actin gamma 1 | -0.0337212 |
| ENO1 | enolase 1, (alpha) | -0.0326233 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0325741 |
| CANX | calnexin | -0.0324853 |
| COL5A1 | collagen, type V, alpha 1 | -0.0324212 |
| PLIN2 | perilipin 2 | -0.0323942 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0322737 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0321628 |
| GNAS | GNAS complex locus | -0.0320856 |
| CLMP | CXADR-like membrane protein | -0.0316023 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0306115 |
| TMEM132D | transmembrane protein 132D | -0.0299939 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0297165 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0294722 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0294323 |
| RPS24 | ribosomal protein S24 | -0.0292146 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0284931 |
| SQSTM1 | sequestosome 1 | -0.0284409 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0284103 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0280271 |
| ADM | adrenomedullin | -0.0278404 |
| MMP12 | matrix metallopeptidase 12 | -0.0276149 |
| MT2A | metallothionein 2A | -0.0275367 |
| TPM4 | tropomyosin 4 | -0.0273101 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.026969 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0265972 |
| DIAPH2 | diaphanous-related formin 2 | -0.0264431 |
| INHBA | inhibin, beta A | -0.0262089 |
| RPS6 | ribosomal protein S6 | -0.0261109 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259926 |
| KRT19 | keratin 19, type I | -0.0254705 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0252584 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0248982 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0247664 |
| RND3 | Rho family GTPase 3 | -0.0245906 |
| NAV1 | neuron navigator 1 | -0.0245461 |
| RPL35A | ribosomal protein L35a | -0.0245189 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.02434 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239911 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0233989 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0233194 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0228213 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0226865 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0225205 |
| EFNA5 | ephrin-A5 | -0.02223 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0222279 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0219395 |
| CAVIN1 | caveolae associated protein 1 | -0.021714 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0216398 |
