| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bicalutamide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bicalutamide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0775752 |
| TXNIP | thioredoxin interacting protein | 0.0648811 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0638574 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0615807 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0538736 |
| SMOX | spermine oxidase | 0.051388 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0480866 |
| NRP1 | neuropilin 1 | 0.0466926 |
| CENPF | centromere protein F, 350/400kDa | 0.0454435 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0450786 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0427238 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0418492 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0390948 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.037803 |
| OGA | O-GlcNAcase | 0.0372528 |
| PELO | pelota homolog (Drosophila) | 0.0361703 |
| MKI67 | marker of proliferation Ki-67 | 0.0348242 |
| OSMR | oncostatin M receptor | 0.0338964 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0335705 |
| NTN4 | netrin 4 | 0.0334362 |
| KSR1 | kinase suppressor of ras 1 | 0.0331324 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0328741 |
| TMEM156 | transmembrane protein 156 | 0.0326029 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0324871 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0324162 |
| ADD3 | adducin 3 (gamma) | 0.0323758 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0319627 |
| WDR26 | WD repeat domain 26 | 0.0317271 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0314919 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0313544 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0310183 |
| RUNX2 | runt-related transcription factor 2 | 0.0306383 |
| DST | dystonin | 0.0301386 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0296828 |
| VMP1 | vacuole membrane protein 1 | 0.0295084 |
| CAB39 | calcium binding protein 39 | 0.0292633 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0292424 |
| CD109 | CD109 molecule | 0.0285622 |
| IL6ST | interleukin 6 signal transducer | 0.0275977 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0274462 |
| RNF145 | ring finger protein 145 | 0.0270098 |
| SMAD3 | SMAD family member 3 | 0.0270028 |
| VEGFA | vascular endothelial growth factor A | 0.0268539 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0268298 |
| YBX3 | Y box binding protein 3 | 0.0251977 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0248535 |
| CD44 | CD44 molecule (Indian blood group) | 0.0244535 |
| ETNK1 | ethanolamine kinase 1 | 0.0243124 |
| HOMER2 | homer scaffolding protein 2 | 0.0241299 |
| ARRDC3 | arrestin domain containing 3 | 0.0238923 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0236366 |
| AHR | aryl hydrocarbon receptor | 0.0235024 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0233912 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0231868 |
| COPA | coatomer protein complex, subunit alpha | 0.0230422 |
| TMF1 | TATA element modulatory factor 1 | 0.0228864 |
| VCL | vinculin | 0.0228453 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0228047 |
| RBM39 | RNA binding motif protein 39 | 0.0226609 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0223736 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0223192 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0223033 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0222846 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0221017 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0220734 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.02202 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0218831 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0218183 |
| DUSP5 | dual specificity phosphatase 5 | 0.0214785 |
| FNBP1 | formin binding protein 1 | 0.0213907 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0208525 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0202614 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.020217 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0201226 |
| RAB31 | RAB31, member RAS oncogene family | 0.0199777 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0198708 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0197874 |
| RNF24 | ring finger protein 24 | 0.0196437 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0195852 |
| RAB8B | RAB8B, member RAS oncogene family | 0.019538 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0194249 |
| TPR | translocated promoter region, nuclear basket protein | 0.0193268 |
| NEK7 | NIMA-related kinase 7 | 0.0192896 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.019287 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0191896 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0188917 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0188426 |
| HELZ | helicase with zinc finger | 0.0188182 |
| USP12 | ubiquitin specific peptidase 12 | 0.0187418 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.018696 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0186665 |
| CORO1C | coronin, actin binding protein, 1C | 0.018646 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0182474 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0182121 |
| GOLT1B | golgi transport 1B | 0.0181327 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0180394 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0179767 |
| FMN1 | formin 1 | 0.0179186 |
| STK24 | serine/threonine kinase 24 | 0.0178759 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.017813 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.265164 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.223622 |
| FN1 | fibronectin 1 | -0.216778 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.211321 |
| PTMA | prothymosin, alpha | -0.179502 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.138148 |
| HMGA2 | high mobility group AT-hook 2 | -0.131982 |
| TMSB10 | thymosin beta 10 | -0.119603 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.116937 |
| SQSTM1 | sequestosome 1 | -0.113206 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.105868 |
| HLA-B | major histocompatibility complex, class I, B | -0.0956622 |
| S100A6 | S100 calcium binding protein A6 | -0.0878337 |
| FTL | ferritin, light polypeptide | -0.0804022 |
| VIM | vimentin | -0.0799849 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0760713 |
| ACTG1 | actin gamma 1 | -0.0726192 |
| CANX | calnexin | -0.0706804 |
| TMSB4X | thymosin beta 4, X-linked | -0.0701918 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0699726 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0656049 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0652317 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0641429 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0623542 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0603073 |
| ENO1 | enolase 1, (alpha) | -0.0594052 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0585285 |
| STC2 | stanniocalcin 2 | -0.0575223 |
| ITGA1 | integrin, alpha 1 | -0.0553988 |
| IER3 | immediate early response 3 | -0.0543386 |
| S100A10 | S100 calcium binding protein A10 | -0.0542971 |
| RPL35A | ribosomal protein L35a | -0.0540385 |
| PLIN2 | perilipin 2 | -0.0508533 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0501196 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0500261 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0499648 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0498221 |
| LMNA | lamin A/C | -0.0494484 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0488643 |
| POTEF | POTE ankyrin domain family, member F | -0.0479519 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0472972 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0468796 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0436335 |
| RACK1 | receptor for activated C kinase 1 | -0.0435758 |
| RPS24 | ribosomal protein S24 | -0.043384 |
| HMGA1 | high mobility group AT-hook 1 | -0.0430193 |
| RPL37A | ribosomal protein L37a | -0.042634 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0426072 |
| CADM1 | cell adhesion molecule 1 | -0.0424026 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0415849 |
| INTS6 | integrator complex subunit 6 | -0.0414825 |
| TMEM165 | transmembrane protein 165 | -0.0405239 |
| RPS8 | ribosomal protein S8 | -0.0403556 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0402899 |
| RPL31 | ribosomal protein L31 | -0.0396687 |
| RPL26 | ribosomal protein L26 | -0.0389117 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.038583 |
| RPLP1 | ribosomal protein, large, P1 | -0.0384841 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0380001 |
| RAI14 | retinoic acid induced 14 | -0.037979 |
| B2M | beta-2-microglobulin | -0.0379016 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0377159 |
| SYT1 | synaptotagmin I | -0.0375321 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0371962 |
| MT2A | metallothionein 2A | -0.0353221 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0351525 |
| ASPH | aspartate beta-hydroxylase | -0.0347288 |
| CALR | calreticulin | -0.0347221 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0340523 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0338645 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0336422 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.03361 |
| RPS29 | ribosomal protein S29 | -0.0334228 |
| RPL38 | ribosomal protein L38 | -0.0331418 |
| CTSD | cathepsin D | -0.032822 |
| RPL34 | ribosomal protein L34 | -0.0326365 |
| S100A9 | S100 calcium binding protein A9 | -0.0322675 |
| RPL9 | ribosomal protein L9 | -0.031891 |
| LRRC23 | leucine rich repeat containing 23 | -0.0317666 |
| RPS21 | ribosomal protein S21 | -0.0312494 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.031219 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0312071 |
| RPS25 | ribosomal protein S25 | -0.0310359 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0309008 |
| AEBP2 | AE binding protein 2 | -0.0308492 |
| HLA-A | major histocompatibility complex, class I, A | -0.0297733 |
| RPS27A | ribosomal protein S27a | -0.029656 |
| RPL23 | ribosomal protein L23 | -0.0293738 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0293465 |
| RPS11 | ribosomal protein S11 | -0.0292018 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0291823 |
| RPS27 | ribosomal protein S27 | -0.0289708 |
| RPL37 | ribosomal protein L37 | -0.0288645 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0287988 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0280936 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0280117 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0277835 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0276225 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0276103 |
| RPS19 | ribosomal protein S19 | -0.027564 |
