Bicuculline Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. (Chemical Entities of Biological Interest Ontology, CHEBI_3092)
External Link http://ctdbase.org/detail.go?type=chem&acc=D001640
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Genes

17 genes/proteins interacting with the chemical Bicuculline from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ARC activity-regulated cytoskeleton-associated protein
CREB1 cAMP responsive element binding protein 1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
HDAC5 histone deacetylase 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MPDZ multiple PDZ domain protein
NCOR2 nuclear receptor corepressor 2
NGF nerve growth factor (beta polypeptide)
OXTR oxytocin receptor
RARA retinoic acid receptor, alpha
TH tyrosine hydroxylase