| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimatoprost_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.134759 |
| ASPH | aspartate beta-hydroxylase | 0.0574006 |
| MSN | moesin | 0.0562679 |
| CALR | calreticulin | 0.0536766 |
| FN1 | fibronectin 1 | 0.0480949 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0435953 |
| COL5A1 | collagen, type V, alpha 1 | 0.0425934 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.040188 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0374685 |
| PRSS23 | protease, serine, 23 | 0.0370864 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0359877 |
| CDH13 | cadherin 13 | 0.034783 |
| CANX | calnexin | 0.034589 |
| DST | dystonin | 0.0337697 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0328808 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0318747 |
| RRM2 | ribonucleotide reductase M2 | 0.0316959 |
| RAI1 | retinoic acid induced 1 | 0.0307152 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0302842 |
| TMSB4X | thymosin beta 4, X-linked | 0.0298996 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0297237 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0295969 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0290577 |
| DSPP | dentin sialophosphoprotein | 0.0281608 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0275716 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0264261 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0262908 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0260365 |
| HDAC9 | histone deacetylase 9 | 0.0255898 |
| VEGFC | vascular endothelial growth factor C | 0.0254603 |
| PTMA | prothymosin, alpha | 0.0243307 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0238985 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0237752 |
| ENO1 | enolase 1, (alpha) | 0.0229588 |
| LDHA | lactate dehydrogenase A | 0.0227236 |
| NEK7 | NIMA-related kinase 7 | 0.0226268 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0221869 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0221124 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.021565 |
| SET | SET nuclear proto-oncogene | 0.0213561 |
| EZR | ezrin | 0.0211351 |
| AFDN | afadin, adherens junction formation factor | 0.021034 |
| TPM3 | tropomyosin 3 | 0.0207807 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0206963 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.020532 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.020022 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0192852 |
| RASAL2 | RAS protein activator like 2 | 0.0192442 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0192057 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0187673 |
| COPA | coatomer protein complex, subunit alpha | 0.018622 |
| APP | amyloid beta (A4) precursor protein | 0.0186033 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0183524 |
| MCL1 | myeloid cell leukemia 1 | 0.0183227 |
| HMGB2 | high mobility group box 2 | 0.0181671 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0181079 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0175484 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0171096 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0170758 |
| CDC73 | cell division cycle 73 | 0.0170713 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0169403 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0167661 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0165926 |
| PLXNA2 | plexin A2 | 0.0163664 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0163624 |
| FAM13B | family with sequence similarity 13, member B | 0.0157979 |
| TMF1 | TATA element modulatory factor 1 | 0.0156824 |
| CYTH3 | cytohesin 3 | 0.0156647 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0154437 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0154093 |
| PTK2 | protein tyrosine kinase 2 | 0.0153237 |
| TUBA1B | tubulin, alpha 1b | 0.0152786 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.015239 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0151803 |
| RPS12 | ribosomal protein S12 | 0.0149603 |
| LAMC2 | laminin, gamma 2 | 0.0147891 |
| CERS2 | ceramide synthase 2 | 0.0147242 |
| DIAPH3 | diaphanous-related formin 3 | 0.0146579 |
| KIF18B | kinesin family member 18B | 0.0145317 |
| MED13L | mediator complex subunit 13-like | 0.0145281 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0145074 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0144802 |
| E2F7 | E2F transcription factor 7 | 0.0144768 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0144144 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0142926 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0142379 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0142263 |
| S100A6 | S100 calcium binding protein A6 | 0.0142216 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0141494 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0141211 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0140777 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0140032 |
| TMEM87A | transmembrane protein 87A | 0.0139416 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0138797 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0138754 |
| CORO1C | coronin, actin binding protein, 1C | 0.0138131 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0133645 |
| CIP2A | cellular inhibitor of PP2A | 0.0132998 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0131737 |
| PLK2 | polo-like kinase 2 | 0.0130833 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.354571 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.112649 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.108128 |
| LOXL2 | lysyl oxidase-like 2 | -0.101326 |
| MT2A | metallothionein 2A | -0.100146 |
| FBN1 | fibrillin 1 | -0.0951572 |
| S100A10 | S100 calcium binding protein A10 | -0.094175 |
| COL1A2 | collagen, type I, alpha 2 | -0.092049 |
| HLA-B | major histocompatibility complex, class I, B | -0.0811703 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.079601 |
| TMSB10 | thymosin beta 10 | -0.0757276 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0684722 |
| CCND1 | cyclin D1 | -0.0683533 |
| CD99 | CD99 molecule | -0.0658589 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0652022 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0633624 |
| FTL | ferritin, light polypeptide | -0.059531 |
| TPM4 | tropomyosin 4 | -0.0593356 |
| POTEF | POTE ankyrin domain family, member F | -0.0587671 |
| LMNA | lamin A/C | -0.0585027 |
| COL3A1 | collagen, type III, alpha 1 | -0.0577492 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0570777 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0548579 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0541572 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0537503 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0499097 |
| SQSTM1 | sequestosome 1 | -0.0481632 |
| AHNAK | AHNAK nucleoprotein | -0.0451946 |
| COL5A2 | collagen, type V, alpha 2 | -0.0440137 |
| STC1 | stanniocalcin 1 | -0.043352 |
| HLA-C | major histocompatibility complex, class I, C | -0.0430777 |
| MYO9B | myosin IXB | -0.0418321 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0413754 |
| CTSB | cathepsin B | -0.0407152 |
| RPL35A | ribosomal protein L35a | -0.040657 |
| ACTG1 | actin gamma 1 | -0.0398354 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0396601 |
| RPS23 | ribosomal protein S23 | -0.0396209 |
| SBF2 | SET binding factor 2 | -0.039579 |
| ANXA2 | annexin A2 | -0.0392211 |
| PLAT | plasminogen activator, tissue | -0.0391345 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.039123 |
| PKM | pyruvate kinase, muscle | -0.0389433 |
| GPC6 | glypican 6 | -0.0389294 |
| NAV1 | neuron navigator 1 | -0.038004 |
| RRBP1 | ribosome binding protein 1 | -0.0373679 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0370777 |
| RPL23 | ribosomal protein L23 | -0.0366882 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0361156 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0355018 |
| RPL28 | ribosomal protein L28 | -0.0353173 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0349614 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0347856 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0347701 |
| NDRG1 | N-myc downstream regulated 1 | -0.0338265 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0333883 |
| RPL32 | ribosomal protein L32 | -0.0333702 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0329221 |
| HDLBP | high density lipoprotein binding protein | -0.0324474 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0323555 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0323436 |
| MYOF | myoferlin | -0.0321113 |
| FLNB | filamin B, beta | -0.0320432 |
| RPS6 | ribosomal protein S6 | -0.0319261 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0318508 |
| RPS19 | ribosomal protein S19 | -0.0316602 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0315576 |
| RPS5 | ribosomal protein S5 | -0.0314758 |
| RPS11 | ribosomal protein S11 | -0.0313452 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0313083 |
| RPS13 | ribosomal protein S13 | -0.0311424 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0310527 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0303102 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0302767 |
| RPS8 | ribosomal protein S8 | -0.0294167 |
| GNAS | GNAS complex locus | -0.0294004 |
| OPTN | optineurin | -0.0293767 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0293177 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0291926 |
| RPS15 | ribosomal protein S15 | -0.0288385 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0287256 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0286167 |
| UBC | ubiquitin C | -0.0285368 |
| RPLP2 | ribosomal protein, large, P2 | -0.0281461 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.028106 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280628 |
| MTDH | metadherin | -0.0280327 |
| CLU | clusterin | -0.0280302 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0279351 |
| RPL19 | ribosomal protein L19 | -0.027916 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0277974 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0277338 |
| NAV2 | neuron navigator 2 | -0.0275612 |
| TAOK1 | TAO kinase 1 | -0.0273952 |
| ACTN4 | actinin, alpha 4 | -0.0273838 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0272751 |
| FUS | FUS RNA binding protein | -0.0268489 |
| RPL31 | ribosomal protein L31 | -0.0265917 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0265825 |
| USP34 | ubiquitin specific peptidase 34 | -0.0264374 |
