| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.128619 |
| SMAD3 | SMAD family member 3 | 0.0630144 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0549868 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0421705 |
| MYO1E | myosin IE | 0.040438 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0375523 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0356312 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0352198 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0301446 |
| EFNB2 | ephrin-B2 | 0.0296639 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0295831 |
| PDZD8 | PDZ domain containing 8 | 0.026139 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0255174 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.023983 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0225145 |
| KYNU | kynureninase | 0.0216608 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0215142 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0210562 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.020248 |
| DUSP10 | dual specificity phosphatase 10 | 0.0200072 |
| DST | dystonin | 0.0198727 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0192859 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0190385 |
| TOX3 | TOX high mobility group box family member 3 | 0.0185288 |
| PRSS22 | protease, serine, 22 | 0.0183493 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0180425 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0179538 |
| FNIP2 | folliculin interacting protein 2 | 0.0178783 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0168183 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0168153 |
| HKDC1 | hexokinase domain containing 1 | 0.016651 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.016318 |
| XDH | xanthine dehydrogenase | 0.016247 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0161739 |
| SLK | STE20-like kinase | 0.0157199 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0156461 |
| NTN4 | netrin 4 | 0.0154753 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0154102 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0153788 |
| EREG | epiregulin | 0.0150102 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0145789 |
| YAP1 | Yes-associated protein 1 | 0.0141643 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0141538 |
| ANXA1 | annexin A1 | 0.0141523 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0137525 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0132241 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0129603 |
| TMEM65 | transmembrane protein 65 | 0.0129122 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0127419 |
| DIAPH1 | diaphanous-related formin 1 | 0.0125138 |
| RND3 | Rho family GTPase 3 | 0.0123934 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0123409 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0123178 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0121092 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0119585 |
| FHL2 | four and a half LIM domains 2 | 0.011927 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0118171 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0116773 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0116222 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0114322 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0111215 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0108366 |
| UBAP1 | ubiquitin associated protein 1 | 0.0106959 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0106458 |
| LAMB3 | laminin, beta 3 | 0.0106114 |
| MYOF | myoferlin | 0.0105677 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0102869 |
| TJP1 | tight junction protein 1 | 0.0101032 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0100657 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.00998907 |
| SLTM | SAFB-like, transcription modulator | 0.00995728 |
| SEPTIN9 | septin 9 | 0.00994272 |
| YBX3 | Y box binding protein 3 | 0.00981463 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.00973235 |
| ADORA2B | adenosine A2b receptor | 0.00968738 |
| MCU | mitochondrial calcium uniporter | 0.00965821 |
| SIK3 | SIK family kinase 3 | 0.00964625 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00948179 |
| GOLGA4 | golgin A4 | 0.00941441 |
| GK | glycerol kinase | 0.00934144 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00929417 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.00914636 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.00911744 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.00911009 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.00904522 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.00902553 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.00881356 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.00874479 |
| FAM120A | family with sequence similarity 120A | 0.00862923 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00857106 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.00852006 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00848025 |
| ADM | adrenomedullin | 0.00845667 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00842872 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.00840945 |
| CTSA | cathepsin A | 0.00827475 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.00814816 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.00808739 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00797547 |
| ECE1 | endothelin converting enzyme 1 | 0.00795237 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.146815 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.124844 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120534 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.119524 |
| UBC | ubiquitin C | -0.116078 |
| RNF213 | ring finger protein 213 | -0.107599 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.10573 |
| LYZ | lysozyme | -0.1029 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.101063 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100603 |
| B2M | beta-2-microglobulin | -0.0999067 |
| XAF1 | XIAP associated factor 1 | -0.0939939 |
| SP100 | SP100 nuclear antigen | -0.0919902 |
| PTMA | prothymosin, alpha | -0.0853505 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0826107 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0795344 |
| MX1 | MX dynamin-like GTPase 1 | -0.0787731 |
| HLA-B | major histocompatibility complex, class I, B | -0.0783998 |
| PKM | pyruvate kinase, muscle | -0.0761079 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0733562 |
| RIGI | RNA sensor RIG-I | -0.0715034 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0684646 |
| PERP | PERP, TP53 apoptosis effector | -0.0681439 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0676523 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0675882 |
| TXNIP | thioredoxin interacting protein | -0.0617044 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0594251 |
| MX2 | MX dynamin-like GTPase 2 | -0.0590869 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0582773 |
| PRKCA | protein kinase C, alpha | -0.0563483 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0551787 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0532713 |
| EPCAM | epithelial cell adhesion molecule | -0.051994 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0519094 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.051685 |
| NPSR1 | neuropeptide S receptor 1 | -0.0508689 |
| JUN | jun proto-oncogene | -0.0506298 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0497718 |
| AHNAK | AHNAK nucleoprotein | -0.0480464 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0476862 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0475048 |
| RPL23 | ribosomal protein L23 | -0.0471967 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0467574 |
| HLA-E | major histocompatibility complex, class I, E | -0.0459206 |
| HLA-C | major histocompatibility complex, class I, C | -0.0456375 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.045446 |
| RRBP1 | ribosome binding protein 1 | -0.0446719 |
| RUNX1 | runt-related transcription factor 1 | -0.0442638 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0442545 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0437782 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0432217 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0431189 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.043037 |
| SSH2 | slingshot protein phosphatase 2 | -0.0407968 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0407814 |
| ACTG1 | actin gamma 1 | -0.0405384 |
| MUC20 | mucin 20, cell surface associated | -0.0402153 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0400549 |
| AHI1 | Abelson helper integration site 1 | -0.0398611 |
| NCKAP5 | NCK-associated protein 5 | -0.0397416 |
| RPL34 | ribosomal protein L34 | -0.0395278 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0394589 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0392246 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0380267 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0376318 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.037621 |
| PMP22 | peripheral myelin protein 22 | -0.0376031 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0372948 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0367507 |
| LCN2 | lipocalin 2 | -0.0365938 |
| MSI2 | musashi RNA-binding protein 2 | -0.0364731 |
| NF1 | neurofibromin 1 | -0.0355023 |
| ABLIM1 | actin binding LIM protein 1 | -0.0354475 |
| TMSB10 | thymosin beta 10 | -0.0352905 |
| RPL35A | ribosomal protein L35a | -0.0351602 |
| PLSCR1 | phospholipid scramblase 1 | -0.0350666 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0349394 |
| PHF3 | PHD finger protein 3 | -0.0344525 |
| ATP11A | ATPase, class VI, type 11A | -0.0343678 |
| TRERF1 | transcriptional regulating factor 1 | -0.0343071 |
| PTK2 | protein tyrosine kinase 2 | -0.0338031 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0336149 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0336026 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0333241 |
| ACTN4 | actinin, alpha 4 | -0.0332395 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0331841 |
| H1-0 | H1.0 linker histone | -0.0331744 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.032849 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0324932 |
| EPHB2 | EPH receptor B2 | -0.032294 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0322265 |
| FTL | ferritin, light polypeptide | -0.0319349 |
| CALR | calreticulin | -0.0315522 |
| SQSTM1 | sequestosome 1 | -0.031142 |
| NCOA7 | nuclear receptor coactivator 7 | -0.030863 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0304251 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0302479 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.030137 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0299871 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0298803 |
