| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimatoprost_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.262398 |
| CDH13 | cadherin 13 | 0.122378 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0884968 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0883269 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0868959 |
| NAV2 | neuron navigator 2 | 0.0739012 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0685702 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0658159 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.065226 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0630261 |
| PRELID2 | PRELI domain containing 2 | 0.0602053 |
| PTK2 | protein tyrosine kinase 2 | 0.0564448 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0520959 |
| COL5A1 | collagen, type V, alpha 1 | 0.0518616 |
| CANX | calnexin | 0.0509393 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0494362 |
| FMNL2 | formin-like 2 | 0.0488248 |
| EGFR | epidermal growth factor receptor | 0.0486784 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0483479 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0482217 |
| ASPH | aspartate beta-hydroxylase | 0.0463876 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0459058 |
| AHNAK | AHNAK nucleoprotein | 0.0456312 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0454699 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0454635 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0441217 |
| CADM1 | cell adhesion molecule 1 | 0.0436853 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0435986 |
| APP | amyloid beta (A4) precursor protein | 0.0425163 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0408052 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0392291 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0384833 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0383058 |
| RUNX1 | runt-related transcription factor 1 | 0.0373521 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0371632 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0366825 |
| ATXN1 | ataxin 1 | 0.0365169 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.036287 |
| NDRG1 | N-myc downstream regulated 1 | 0.0351776 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0343498 |
| EFNA5 | ephrin-A5 | 0.0336224 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.033331 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0331585 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0331098 |
| MED13L | mediator complex subunit 13-like | 0.0329616 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0321584 |
| MYO1B | myosin IB | 0.0316678 |
| ANO6 | anoctamin 6 | 0.0313163 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0312209 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0308145 |
| ENO1 | enolase 1, (alpha) | 0.0307928 |
| TMSB4X | thymosin beta 4, X-linked | 0.0307568 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0307244 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0300021 |
| FNIP1 | folliculin interacting protein 1 | 0.0295932 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0289309 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0289272 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0286034 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0284081 |
| DOCK5 | dedicator of cytokinesis 5 | 0.028313 |
| SQSTM1 | sequestosome 1 | 0.0282066 |
| MYO10 | myosin X | 0.0271365 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0268951 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0268719 |
| FBN1 | fibrillin 1 | 0.0265662 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0260923 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.025814 |
| JAK1 | Janus kinase 1 | 0.025511 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0254461 |
| MTDH | metadherin | 0.025373 |
| CCNY | cyclin Y | 0.0253676 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0251142 |
| HIP1 | huntingtin interacting protein 1 | 0.025097 |
| CDK13 | cyclin-dependent kinase 13 | 0.024902 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0247318 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0246373 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0245625 |
| YEATS2 | YEATS domain containing 2 | 0.0245369 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0242656 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.024081 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0239881 |
| USP34 | ubiquitin specific peptidase 34 | 0.023934 |
| PLEC | plectin | 0.0238919 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0238627 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0236511 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0236469 |
| RBM39 | RNA binding motif protein 39 | 0.0233773 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0232458 |
| ARRDC3 | arrestin domain containing 3 | 0.0232415 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0228509 |
| EXOC4 | exocyst complex component 4 | 0.0223857 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0223322 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0223025 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0222741 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0222499 |
| TNS1 | tensin 1 | 0.0222278 |
| YAP1 | Yes-associated protein 1 | 0.0221368 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0221365 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0219683 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0218233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.237131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.196115 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.170467 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.147163 |
| FN1 | fibronectin 1 | -0.137242 |
| MT2A | metallothionein 2A | -0.0983988 |
| VIM | vimentin | -0.0879243 |
| TMSB10 | thymosin beta 10 | -0.0853949 |
| COL1A1 | collagen, type I, alpha 1 | -0.0769978 |
| STC1 | stanniocalcin 1 | -0.0569612 |
| CD44 | CD44 molecule (Indian blood group) | -0.0524971 |
| EGR1 | early growth response 1 | -0.0511137 |
| MAP1B | microtubule-associated protein 1B | -0.049218 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0486377 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0485457 |
| COL1A2 | collagen, type I, alpha 2 | -0.046098 |
| PALLD | palladin, cytoskeletal associated protein | -0.0458476 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0450167 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0419973 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0404627 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0377313 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0375329 |
| INHBA | inhibin, beta A | -0.0368656 |
| POSTN | periostin, osteoblast specific factor | -0.0362765 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0341012 |
| PFN1 | profilin 1 | -0.0340368 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0336569 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.032488 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0322092 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.03083 |
| FTL | ferritin, light polypeptide | -0.030683 |
| OSMR | oncostatin M receptor | -0.0299543 |
| HLA-A | major histocompatibility complex, class I, A | -0.0286004 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0261907 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0260095 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0252326 |
| VCAN | versican | -0.0248111 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0247704 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0247654 |
| TAGLN2 | transgelin 2 | -0.0242026 |
| LIMA1 | LIM domain and actin binding 1 | -0.0227742 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0227636 |
| ATP13A3 | ATPase type 13A3 | -0.0227325 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0222008 |
| B2M | beta-2-microglobulin | -0.0221666 |
| HMGA1 | high mobility group AT-hook 1 | -0.0214658 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0205041 |
| HLA-B | major histocompatibility complex, class I, B | -0.0202452 |
| PKM | pyruvate kinase, muscle | -0.0201781 |
| RRBP1 | ribosome binding protein 1 | -0.0201713 |
| SMAD3 | SMAD family member 3 | -0.0200758 |
| TPI1 | triosephosphate isomerase 1 | -0.0189228 |
| GLIS3 | GLIS family zinc finger 3 | -0.0188322 |
| AXL | AXL receptor tyrosine kinase | -0.0187921 |
| S100A9 | S100 calcium binding protein A9 | -0.0184398 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0183908 |
| TAPBP | TAP binding protein (tapasin) | -0.018002 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0178475 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0177685 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0173215 |
| MYADM | myeloid-associated differentiation marker | -0.0171916 |
| SQLE | squalene epoxidase | -0.0171567 |
| POTEF | POTE ankyrin domain family, member F | -0.0164334 |
| DUSP6 | dual specificity phosphatase 6 | -0.0163747 |
| CTSD | cathepsin D | -0.015833 |
| RPL19 | ribosomal protein L19 | -0.0157578 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0156321 |
| ACTN4 | actinin, alpha 4 | -0.0155974 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0155453 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0155033 |
| RPL35A | ribosomal protein L35a | -0.0154529 |
| RPLP2 | ribosomal protein, large, P2 | -0.0152777 |
| RPS19 | ribosomal protein S19 | -0.0150193 |
| LOXL2 | lysyl oxidase-like 2 | -0.0148549 |
| H1-0 | H1.0 linker histone | -0.0146129 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0145764 |
| KLF6 | Kruppel-like factor 6 | -0.0144306 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.0142022 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0140896 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0140173 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0138985 |
| MX2 | MX dynamin-like GTPase 2 | -0.013879 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0138611 |
| LAMA5 | laminin, alpha 5 | -0.0137171 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0131819 |
| VEGFA | vascular endothelial growth factor A | -0.013073 |
| ECE1 | endothelin converting enzyme 1 | -0.0129638 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0128728 |
| MYL9 | myosin, light chain 9, regulatory | -0.0128166 |
| RPL18 | ribosomal protein L18 | -0.0127105 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0126964 |
| TUBB6 | tubulin, beta 6 class V | -0.0126604 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0126437 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0125903 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0124864 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0124353 |
| CALR | calreticulin | -0.0124127 |
| CCND1 | cyclin D1 | -0.0124118 |
| STK17A | serine/threonine kinase 17a | -0.0121731 |
| AGRN | agrin | -0.0121702 |
